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The morbidity of bone fractures and defects is steadily increasing due to changes in the age pyramid. As such, novel biomaterials that are able to promote the healing and regeneration of injured bones are needed to overcome the limitations of auto-, allo-, and xenografts, while providing a ready-to-use product that may help to minimize surgical invasiveness and duration. In this regard, recombinan
BACKGROUND: Weight-adjusted-waist index (WWI) is an anthropometric index reflecting fat mass and muscle mass, both of which are important factors influencing insulin resistance and inflammation.OBJECTIVES: We aimed to examine the associations of WWI with all-cause, cardiovascular, and noncardiovascular mortality among individuals with type 2 diabetes (T2D) and further investigate whether insulin r
Purpose: There is an an increasing awareness of the importance of health and lifestyle for stroke diseases like spontaneous subarachnoid hemorrhage (SAH). However, the importance of pre-existing medical conditions for clinical course and mortality after SAH has not been studied. The aim of the present study was to identify pre-existing conditions contributing to mortality after SAH. Methods: Data
BACKGROUND AND OBJECTIVES: The extremely rare Rh null phenotype is characterized by the absence of all Rh antigens on erythrocytes. It is divided into the regulator and amorph types based on the underlying genetic background. The more common regulator type depends on critical variants silencing RHAG, which encodes RhAG glycoprotein, necessary for RhD/RhCE expression. Rh null cells have altered e
Patterns of ploidy variation among and within populations can provide valuable insights into the evolutionary mechanisms shaping the dynamics of plant systems showing ploidy diversity. Whereas data on majority ploidies are, by definition, often sufficiently extensive, much less is known about the incidence and evolutionary role of minority cytotypes. Ploidy and proportions of endoreplicated genome
To update the European System for Cardiac Operative Risk Evaluation (EuroSCORE) risk model. A dedicated website collected prospective risk and outcome data on 22 381 consecutive patients undergoing major cardiac surgery in 154 hospitals in 43 countries over a 12-week period (May-July 2010). Completeness and accuracy were validated during data collection using mandatory field entry, error and range
Background: The COVID-19 pandemic has disrupted routine hospital services globally. This study estimated the total number of adult elective operations that would be cancelled worldwide during the 12 weeks of peak disruption due to COVID-19.Methods: A global expert response study was conducted to elicit projections for the proportion of elective surgery that would be cancelled or postponed during t
BACKGROUND AND PURPOSE: In small trials with control groups that receive no intervention, acupuncture has been reported to improve functional outcome after stroke. We studied effects of acupuncture and transcutaneous electrical nerve stimulation on functional outcome and quality of life after stroke versus a control group that received subliminal electrostimulation. METHODS: In a multicenter rando
The self-assembly behavior of a cationic surfactant (dodecyltrimethylammonium, DTA) with DNA as counterion in mixtures of water and n-alcohols (decanol, octanol, hexanol, butanol, and ethanol) was investigated. The phase diagrams were established and the different regions of the phase diagram characterized with respect to microstructure by H-2 NMR, small-angle X-ray scattering (SAXS), and other te
To investigate the evidence behind supposed advantages of insulin detemir over existing therapy (NPH insulin), we carried out a systematic review. We analysed the available documentation presented after registration of the drug by the European drug regulatory authority (EMEA) and approached the data presented at the authority's Internet site. Some data from Food and Drug Administraion (FDA) contri
The surface properties of several modified stainless steel samples were characterized according to their chemical composition, roughness, topography and wettability. The modifications tested were SiF3+ and MoS22+ ion implantation; diamond-like carbon (DLC) sputtering: DLC. DLC-Si-O and SiOx, plasma enhanced chemical vapor deposition (PECVD); autocatalytic Ni-P-PTFE and silica coating. X-ray photoe
objectives: To assess the level of infectious complications and the impact of timing of a single, prophylactic, oral dose of ciprofloxacin 750 mg given either 2 hours before or in conjunction with ultrasound -guided core biopsy of the prostate in men without recognised risk factors and to analyse potential risk factors. Methods: All men undergoing prostate biopsy for elevated prostate specific ant
The agricultural intensification strategies represented by the Green Revolution have since the mid-1960s had a very positive impact on food-grain production in Asia. Presently, however, a post-Green Revolution phase of declining growth in output and productivity is experienced in many of the areas where intensification took place. Partly, this can be explained by a number of environmental problems
Popular Abstract in Swedish Vill man ta en bild av något som rör sig mycket snabbt, krävs det att man använder en kort exponeringstid. Om kamerans slutare är öppen under för lång tid, hinner det man vill fotografera röra sig under tiden filmen exponeras, med resultatet att bilden blir suddig. Kemiska reaktioner där atomer och molekyler är inblandade är exempel på något som sker på väldigt kort tidWhen a low-frequency laser pulse is focused to a high intensity in a gas, the electric field of the laser may become comparable to, or even exceed, the electric field between the electrons and the nucleus in the atom. Under such conditions, through a process known as high-order harmonic generation, bursts of extreme ultraviolet radiation may be emitted, with durations in the attosecond domain (1 a
Recent genome-wide association studies (GWASs) conducted in Asian populations have identified novel risk loci for systemic lupus erythematosus (SLE). Here, we genotyped 10 single-nucleotide polymorphisms (SNPs) in eight such loci and investigated their disease associations in three independent Caucasian SLE case-control cohorts recruited from Sweden, Finland and the United States. The disease asso
We report on the solar-light-mediated degradation of trimethyl phosphate (TMP) and triethyl phosphate (TEP) on hematite and goethite nanoparticles in synthetic air. Adsorption and photoreactions of TMP and TEP were studied by in situ diffuse reflectance Fourier transform infrared spectroscopy (DRIFTS) on dry and water-precovered nanoparticles in dark and under simulated solar light irradiation. Tw
The FACET (Formoterol and Corticosteroid Establishing Therapy) study established that there is a clear clinical benefit in adding formoterol to budesonide therapy in patients who have persistent symptoms of asthma despite treatment with low to moderate doses of an inhaled corticosteroid. We combined the clinical results from the FACET study with an expert survey on average resource use in connecti
Aim To investigate whether nurses could be a useful tool for improving the reporting rate of adverse drug reactions (ADRs). Furthermore, we wanted to study how physicians working at the study departments would respond to nurses as reporters of ADRs and if the reporting from the nurses affected the reporting rate from the physicians. Methods Three departments of internal medicine and one unit for o
Popular Abstract in Swedish Medfödda hjärtfel (congenital heart defects,CHD) förekommer hos nästan 1 % av alla födda barn. En del lindriga hjärtfel spontanläker, men de flesta hjärtfel måste opereras i läkande eller lindrande syfte. Stora kirurgiska framsteg har gjorts på senare år. Hjärtfel som tidigare icke ansågs möjliga att åtgärda kan nu opereras, och många operationer utföres tidigt i livet,The aim of this study was to evaluate new MR techniques permitting qualitative and quantitative analysis of cardiac function and measurement of velocity and flow, and later on contrast-enhanced MR angiography, techniques largely unexplored in children with CHD. Infants with tetralogy of Fallot and pulmonary atresia with ventricular septal defect were examined pre-operatively. MRI was found to be a
