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This thesis work concerns studies of two rare-earth-ions, praseodymium (Pr3+) and europium (Eu3+), doped into a yttrium orthosilicate (Y2SiO5) crystal for applications in quantum computing. The nuclear spin levels of these ions can have very long coherence times, up to several hours. Coherence can also be effectively transferred between the optical and hyperfine levels. These systems, therefore, h
BackgroundMultigene expression assays for molecular subtypes and biomarkers can aid clinical management of early invasive breast cancer. Based on RNA-sequencing we aimed to develop single-sample predictor (SSP) models for conventional clinical markers, molecular intrinsic subtype and risk of recurrence (ROR).MethodsA uniformly accrued breast cancer cohort of 7743 patients with RNA-sequencing data
Introduction: The lungs are the second most common site for metachronous metastases in colorectal cancer. No treatment algorithm is established, and the role of adjuvant chemotherapy is unclear. This study aimed to map pulmonary recurrences in a modern multimodal treated population, and to evaluate survival depending on management. Methods: Retrospective study based on the COLOFOL-trial population
Background: Human breast cancer most frequently originates within a well-defined anatomical structure referred to as the terminal duct lobular unit (TDLU). This structure is endowed with its very own lobular fibroblasts representing one out of two steady-state fibroblast subtypes—the other being interlobular fibroblasts. While cancer-associated fibroblasts (CAFs) are increasingly appreciated as co
Background and Purpose: In magnetic resonance imaging (MRI) only radiotherapy computed tomography (CT) is excluded. The method relies entirely on synthetic CT images generated from MRI. This study evaluates the compatibility of a commercial synthetic CT (sCT) with an accelerated commercial deep learning reconstruction (DLR) in MRI-only prostate radiotherapy. Materials and Methods: For a group of 2
Abstract Trying to preserve the forest is an important issue considering its tremendous impact on the ecosystem and subsequently on humans and their lives. On the other hand, humans have changed the area of the forest in different ways. Therefore, investigating the human impact and helping to prevent the destruction of the forest plays a vital role in preserving biodiversity and maintaining ecosys
Det är fascinerande att fundera över hur den antika människan förstod kroppen och i synnerhet kopplingen mellan känslor och kroppen. I syfte att förstå det bättre har jag i den här uppsatsen studerat hur Vergilius använder medicinska, fysiologiska eller anatomiska termer för att beskriva känslor och psykologiska tillstånd. Jag har också studerat vad som är den metaforiska betydelsen av dessa begreIt is fascinating to think on how antiquity pictured the human body and especially the connection between the mind and body. To better understand this I have studied how Virgil uses medical, anatomical, and physiological terminology to describe feelings and psychological phenomena. Furher, I have studied the metaphoric value of this terminology and sought for explanations in differences between Vi
I simulate the collision of satellite galaxies with the Milky Way and observe the effects that this has on the orbits of the globular cluster populations within both the Milky Way and the satellite galaxies. This is done in order to investigate whether some of the Milky Way's globular clusters could have been donated from satellite galaxies which have been tidally stripped, since it is believe
The root-associated habit has evolved on numerous occasions in different fungal lineages, suggesting a strong evolutionary pressure for saprotrophic fungi to switch to symbiotic associations with plants. Species within the ubiquitous, saprotrophic genus Mycena are frequently major components in molecular studies of root-associated fungal communities, suggesting that an evaluation of their trophic
Background: Haemodynamic studies in children are rare and most studies have included few subjects in the youngest age group. Haemodynamic variables need to be indexed to establish a reference of normality that is valid in all populations. The traditional way to index haemodynamic variables with body surface area (BSA) is complicated in young children due to its non-linear relationship with body we
Den globala uppvärmningen gör sig ständigt påmind genom extremväder och naturkatastrofer. Vid klimatkonferensen COP21 år 2015 undertecknade i stort sett alla världens länder Parisavtalet med målet att temperaturökningen ska begränsas. För att uppnå Parisavtalets mål ligger en stor del i att länder behöver minska sina utsläpp av växthusgaser. Sverige har minskat sina utsläpp med 35 procent sedan 19Global warming is constantly reminding us of its presence through extreme weather and natural disasters. At the COP21 climate conference in 2015, almost every country in the world signed the Paris Agreement with the aim of limiting temperature increase. The countries need to reduce their greenhouse gas emissions to achieve this. Since 1990, Sweden has reduced its emissions by 35 percent, and in 20
With constant upgrades in 3d-modeling software, even previously functional and validated animated facial expressions can be updated. The present work seeks to provide such an additional upgraded set of tools for researchers to use interested in e.g. emotional facial expressions, and contains two experiments. One where static facial expressions are tested in three different ways and a second experi
Creasing of paperboard is an essential operation to obtain a well defined shape and strength of a package. The creasing tool consists of one male and one female creasing plate. The male plate presses the paperboard into the female plate and introduces damage in the creasing zone. Today the standard creasing operation at Tetra Pak is that the male creasing plate presses the top ply (print side) of
I Laval målet så höll Domstolen fast att fackförbund ska hållas ansvariga för överträdelser av EU-rätten i form av blockering av den fria rörelsen för tjänster. Den här uppsatsen har som mål att undersöka det juridiska ansvaret för fackförbund och andra organisationer som är skilda från staten och som kan utöva statsliknande krafter – det jag kallar semi-statliga organisationer. De utövar vid tillIn the Laval case the Court set firm that trade unions should be held responsible for transgressions of EU law in the form of obstructing the freedom to provide services. This paper has the aim to investigate the legal responsibility of trade unions and other organisations separate from the state that can still wield state-like powers – what I call quasi-governmental organisations. They wield the
Timber-concrete composite structures were originally developed for upgrading existing timber oors, but during last decades, they have new applications in multistorey buildings. Most of the research performed on these structures has focused on systems in which wet concrete is cast on top of timber beams with mounted connectors. Recently investigations on composite systems were performed at Luleå Un
SARS [Severe Acute Respiratory Syndrome] penetrated China in spring of 2003, created havoc in the social society, exposed weaknesses within the political system and pushed the nation towards a crisis of confidence. At the same time the crisis revitalised the Party's position, brought people from different social stratum together and had a beneficial impact on the populace's knowledge on he
Freedom of movement is a necessity for the European Union. According to Article 8a EEC, which was inserted by the Single European Act in 1987, the Member States of the European Union have committed themselves to achieve an internal market and thus abolish all obstacles that may impede the free movement of goods, services, capital and persons. The right to free movement of persons is one of these f
