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Abstract Through the use of chimeric CXCR4/CCR5 receptors we have previously shown that CCR5-tropic (R5) HIV-1 isolates acquire a more flexible receptor use over time, and that this links to a reduced viral susceptibility to inhibition by the CCR5 ligand RANTES. These findings may have relevance with regards to the efficacy of antiretroviral compounds that target CCR5/virus interactions. Compartme

Diagnosis of first paroxysmal events at the children’s ER at a Swedish Regional hospital – including a one year follow up Background First epileptic seizures can be difficult to diagnose properly as there are many differential diagnoses including provoked seizures, febrile seizures, syncope, breath holding spells and psychogenic seizures. Many articles highlight the importance of a diligent medi

I dagens samhälle kämpar företag för att höras och synas i det överflöd av information som finns tillgänglig. Ett särskiljande kännetecken har därmed blivit ett mycket viktigt kommunikationsmedel för företag. I detta kännetecken ligger ofta ett betydande värde i form av goodwill och image och attityd hos förbrukarna. Inte sällan är det hela koncept som förmedlas i ett komplicerat byggande av relat

Course evaluation Physical Geography and Ecosystem Science LU Course Summary for Remote sensing for landscape studies, NGEA03, vt 2021 Course coordinator: Ulrik Mårtensson Teachers in the course: Anna Maria Jönsson, Jonas Ardö Number of students: 15 registered students Grade distribution: 1 UK, 0 G, 14 VG. Evaluation Summary of the course evaluation Number of survey responses: 12, of which is 80 %

https://www.nateko.lu.se/sites/nateko.lu.se/files/2023-03/NGEA03%20course%20evaluation%20summary.pdf - 2026-05-26

This is the first multi-district Standardised Patient (SP) study in South Africa. It measures the quality of TB screening at primary healthcare (PHC) facilities. We hypothesise that TB screening protocols and best practices are poorly adhered to at the PHC level. The SP method allows researchers to observe how healthcare providers identify, test and advise presumptive TB patients, and whether thisThis is the first multi-district Standardised Patient (SP) study in South Africa. It measures the quality of TB screening at primary healthcare (PHC) facilities. We hypothesise that TB screening protocols and best practices are poorly adhered to at the PHC level. The SP method allows researchers to observe how healthcare providers identify, test and advise presumptive TB patients, and whether this

Background: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (FcεRI) expression. Recent discoveries in uncontrolled asthma suggest that the appearance of FcεRI-expressing alveolar mast cells may be a novel disease-specific feature of allergic asthma. This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild aller

This thesis analyzes the legitimacy of the United States’ sanctions against Cuba during the Cold War from a human rights perspective. It applies four theoretical frameworks: John Locke’s natural rights theory, Marxism, liberal internationalism, and the UN Charter. Using an idea analysis method, the study examines how these frameworks interpret the purpose, means, and effects of the sanctions. Empi

Popular Abstract in English An increased risk of pre-cancer lesions of the cervix among HIV-infected women, and the positive impact of HIV treatment on its outcome has been reported globally. However there is paucity of information from west Africa with genetically distinct viral strains. Considering that HIV strains differ in the rate and pattern of HIV disease progression, a different outcome isBackground: The highest numbers of HIV-infected women are in sub- Saharan Africa, where the natural progression of HIV disease in the absence of treatment results in death before the onset of invasive cervical cancer. With improved access to treatment, several studies outside West Africa demonstrated an increased risk of pre-invasive cervical lesions among HIV-infected women and the positive impac

This Master’s Thesis has shown possible applications of genetic optimization algorithms (GA) within design. A framework for structural optimization with genetic algorithms was built and used to show the possibilities of using GA to create concept designs given just the boundary conditions and requirements of a structure. A comparison between the optimization of the load bearing beam of an automate

BACKGROUND AND AIM: In many places worldwide there is an ongoing urbanization, often achieved through densification. An increased number of inhabitants in an area often leads to both increased traffic and placement of new buildings closer to roads, and thus increased population exposure to road traffic noise. The aim of the study was to estimate and compare the health impacts of road traffic noise

The archivist Martin Grass defines personal archives as that they do not have to adapt to guidelines when it comes to the culling or preservation of the material, the submitting of the material to an archive is not done directly after the material is created or collected and that they often concern broader subjects. In this thesis I study the creator of the personal archives and the driving forces

The starting point DESIGN FOR ALL and the conception SMART ARCHITECTURE have been leading themes to the proposal MOVING IN PATTERNS. Smart architecture, in the sense to balance out individuals' diverse capabilities, has lead to a stimulating enviroment for all. The term ACCESS FOR ALL concerns everybody from disabled people to people of different ages and languages. The human aspect has been k

Premiär 14 oktober 2024 Travelling and seeing things anew were essential to the writing of one of the most beloved and translated Swedish poets of modern times, Tomas Tranströmer. Before receiving the Nobel Prize in Literature in 2011, he had already been translated into around 60 languages and had travelled the world to meet his audience in person. Alongside his writing, he was an engaged and att

https://www.lmc.lu.se/ljudbanken/pendulum-memories - 2026-05-25

Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami

BackgroundCognitive function is often impaired for cardiac arrest (CA) survivors as an effect of hypoxic-ischemic brain injury. An important factor in CA recovery is global functional outcome, commonly assessed with the modified Rankin Scale (mRS). Little is known about the role of cognition as a potential predictor of outcome following CA.ObjectiveTo investigate cognitive function at hospital dis

Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T

We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai