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OBJECTIVE: The microenvironment of colon cancer (CC) is heterogeneous including cells of myeloid lineage affecting tumor growth and metastasis. Two functional subtypes of myeloid cells have been identified; one (M1) is tumor-inhibitory and the other one (M2) is tumor-promoting. Whether the three myeloid markers EMR1, CD206 and CD86 are expressed only in the infiltrating myeloid cells or also in th

Modern well-insulated and highly glazed buildings experience increased overheating, even in cold climates. The study focused on external and internal passive solar shadings on a south-oriented façade, having predetermined that external and internal shadings’ main function is solar heat gain and glare protection, respectively. A daytime-occupied office space with several external shading geometry v

Additive manufacturing (AM), which was first applied for rapid prototyping, is now becoming a real option for small-batch production of final products. Further expansion of AM is closely correlated to production costs. AM can only become competitive to traditional manufacturing methods if a product is designed for AM already from the beginning as it is an expensive technology that should only be a

REST is a transcriptional repressor that targets a group of neuronal genes in non-neuronal cells. In embryonic stem (ES) cells, REST has been implicated in controlling the expression of transcription factor genes that are crucial for lineage determination and for maintaining ES cell potential. Here, we asked whether REST directly regulates neural-specifying genes in mouse ES cells using siRNA-medi

Abstract in Undetermined[Context and motivation] There is considerable flexibility in requirements specifications (both functional and non-functional), as well as in the features of available OSS components. This allows a collaborative matching and negotiation process between stakeholders such as: customers, software contractors and OSS communities, regarding desired requirements versus available

Popular Abstract in Swedish Villkoren för utbildning och undervisning förändras i väsentliga avseenden i takt med samhällets tilltagande komplexitet. Det är många gånger svårt för både lärare och elever att veta hur man på bästa sätt ska orientera sitt pedagogiska handlande. Med utgångspunkt från tre pedagogiska kontexter - grundskolan, de särskilda ungdomshemmen och grundskollärarutbildningen - pPedagogical practice is, in several important considerations, contradictory in character. In this dissertation attenention is drawn towards the field of tension that prevails between pedagogical action, which can be descibed in terms of strategic processes and communicative pedagogical action. While the former places the preconditions for effective knowledge development of the individual at the ce

Uppsatsen syftar till att söka förståelse till varför tvister mellan fackförbund om vem som ska teckna kollektivavtal uppstår. Arbetsmarknadernas parter är i allmänhet ense om att det som regel bör finnas ett kollektivavtal på varje avtalsområde. Kollektivavtalets speciella rättsverkningar gör det viktigt för fackförbunden att vara avtalspart i ett kollektivavtal. Kollektivavtalet sätter i stor utThe aim of this essay is to seek understanding about why conflicts appear between trade unions regarding which one of them should sign the collective agreement in the workplace. The labour market parties are in general in an agreement that there should only be one applicable collective agreement in every area of work. The unique effects of the collective agreement make it crucial for the trade uni

This essay concerns the use of judicial preview and review in Sweden and Germany. First, it is presented how judicial preview and review works in each respective system, and then the procedure of the enactment of a law is presented. In the analysis it is discussed how differently the law would've been treated, if Sweden had the same judicial review as in Germany. The conclusion is that the gr

I den här studien undersöks hur fem musiklärare som är, eller har varit, verksamma i anpassad grundskola beskriver hur de arbetar med musikalisk kunskapsutveckling, delaktighet och måluppfyllelse. Undersökningen baseras på semistrukturerade intervjuer och hela arbetet vilar på socialkonstruktivismen som vetenskapsteori. Ämnesvalet grundar sig i en nyfikenhet kring hur vi som framtida lärare kan arThis study investigates how five music teachers that are, or have been, working in Swedish compulsory school for pupils with intellectual disabilities describe how they are working with development of musical knowledge, inclusion and goal attainment. The study is conducted by using semistructured interviews and is grounded in social constructivism as its scientific theoretical framework. The selec

Rapporten behandlar arbetsmiljön vid termisk ogräsbekämpning. Metoden innebär att ogräset hettas upp med hjälp av gaslågor. Både stora fordonsburna och mindre handdrivna används. Det som från arbetsmiljösynpunkt är speciellt med metoden är de risker som är förknippade med gasolanvändningen. De allvarligaste problemen med de aggregat som studerats har varit heta och oskyddade plåtar, heta avgaser o

In temperate regions, many vector-borne parasites maximise their transmission prospects by adjusting reproduction to seasonal cycles of host susceptibility and vector availability. Nevertheless, in these regions there are areas where environmental conditions are favourable throughout the year, so that parasites could benefit from a year-round transmission strategy. We analysed how different transm

This study investigates online material published in reaction to a Science magazine report showing the absence of peer-review and editorial processes in a set of fee-charging open access journals in Biology. Quantitative and qualitative textual analyses are combined to map conceptual relations in these reactions; and to explore how understandings of scholarly communication and publishing relate to

The extent to which in-situ global mechanical tensioning (GMT) can be used to modify the residual stress state in friction stir (FS) welds is investigated in this article. Residual stress distributions have been determined by synchrotron X-ray and neutron diffraction for four sets of FS welds in high-strength AA7449-W51 and lithium containing AA2199-T8 aerospace aluminum alloys subjected to a syst

This dissertation aims to investigate and analyze people's preparation for retirement. The study has been made through semi-structured interviews with 78 people born between the years 1931-1981 regarding their preparations for retirement. The analysis is based on the model Reflexive Planning for Later Life, coping, bounded rationality, behavioural finance and the concept of governmentality, and

Current trends show that the number of people affected by natural disasters is likely to increase in coming decades. Today, more than half the world's population lives in cities and the number is expected to rise in the future. To make cities safe is therefore vital. Making Cities Resilient is an ongoing global campaign in the area of disaster risk reduction and aims to build resilient cities