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Altered movement patterns and deviating muscular activity in individuals with anterior cruciate ligament injury

Popular Abstract in Swedish Skador i knäleden är vanligt förekommande och främre korsbandsskada drabbar i Sverige årligen mer än 8 per 10 000 personer i åldern 10-64 år. Följderna av skadan kan bli bestående funktionsnedsättning med bl.a. instabilitet, plötsliga och smärtsamma knäledsvikningar och ökad risk för nya skador. Cirka hälften av patienterna utvecklar ledsvikt (artros) 10-15 år efter denThe purpose of this thesis was to increase the understanding of altered movement patterns in individuals with anterior cruciate ligament (ACL) injury in order to improve ACL rehabilitation, and to develop an observational instrument termed Test for Substitution Patterns (TSP) for standardized, quantifiable scoring of altered movement patterns in legs and trunk. In all, 142 participants, 93 with A

Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering

Background: Hardwood spent sulfite liquor (HSSL) is a by-product of acid sulfite pulping process that is rich in xylose, a monosaccharide that can be fermented to ethanol by Scheffersomyces stipitis. However, HSSL also contains acetic acid and lignosulfonates that are inhibitory compounds of yeast growth. The main objective of this study was the use of an evolutionary engineering strategy to obtai

Chromosome dynamics and genomic instablity in neuroblastoma. Three genomic pillars: MYCN amplification, numerical and structural changes.

In this thesis, the main focus has been on the childhood cancer neuroblastoma, one of the most common and lethal childhood tumours. Neuroblastoma has througout the years continued to be a clinical and biological enigma. Our first focus was on one of the most important biological risk factors in neuroblastoma -- amplification of the oncogene MYCN in the tumour cells. Because amplified MYCN typical

Muscle strength and physical education: epidemiological studies of factors in adolescence and their association with later morbidity

Popular Abstract in Swedish Avhandlingen består av fyra delstudier och är tematiskt uppdelad i två delar. I den första delen undersöker jag vilken betydelse betyget i Gymnastik (nuvarande Idrott & Hälsa) har för framtida sjukdom med fokus på rörelseorganen. I den andra delen undersöker jag vilken betydelse isometrisk muskelstyrka (d.v.s. kraft alstrad utan nämnvärd förkortning av muskeln) har Although Physical Education (PE) is a part of the school curriculum in many countries, the association between the performance in PE and later morbidity is largely unknown. An important marker of health, cardiorespiratory fitness is inversely associated with future cardiovascular disease (CVD) and mortality. It has been suggested that muscle strength is associated in a similar way. However, whethe

Integration study on a two-stage fermentation process for the production of biohydrogen

In order to make the hydrogen economy fully sustainable, renewable resources have to be employed for its production. Simulation models, developed with Aspen Plus to calculate mass and energy balances, will be used to integrate the process steps necessary to produce pure hydrogen from biomass in a 2-stage fermentation process. The main challenge is the reduction of water and heat demand connected t

Maskinisk darwinism: teknikens naturhistoria hos Samuel Butler och Gilles Deleuze

This paper provides perspectives on the development of an idea of the machine as a living being in the 20th century by looking at the relationship between the writings of Samuel Butler and Gilles Deleuze concerning the evolution of machines as an extension of—and in competition with—the human organism. Ultimately, Butler and Deleuze both describe a mechanical or “machinic" vitalism and evolutionis

Estimation of Extreme Climatic Thermal Actions in Concrete Structures

The temperature distribution in concrete structures varies due to annual and daily climate variations. Solar radiation, air temperature, wind speed and long-wave radiation affect the temperature in the structure and may cause longitudinal and transversal movements. If these movements are restrained, stresses and strains can be induced which may contribute to cracking. To be able to predict the lon

Personsäkerhet i tunnlar - Inventering

Banverket äger och förvaltar ett stort antal tunnlar samtidigt som planering och byggande pågår för ett flertal tunnlar. Syftet med föreliggande arbete är att öka kunskapen och på sikt förbättra och förenkla processen angående personsäkerhet i tunnlar. Rapporten beskriver det inventeringsarbete som utförts med avseende på både befintliga och nya tunnlar med fokus på personsäkerhet...

Flow and noise investigations of a separate flow exhaust system

A major component of aircraft noise is the jet noise created by the high velocity hot stream exhausting from a jet engine, interacting with itself and with the surrounding cold air. In the present paper the flow and acoustic fields that are generated by two coaxial jets are considered. Numerically, the problem is divided into a flow related part (Navier-Stokes system of equation) and an acoustic p

Assessing the effectiveness of the ‘Green Economic Stimulus’ in South Korea: Evidence from the energy sector

The purpose of this paper is to provide an ex-post evaluation of the effectiveness of the South Korean Green New Deal (GND) as an instrument to deliver both an economic recovery and improved environmental performance. We use the energy sector as the main scope for our analysis when measured against climate-related indicators (e.g. CO2 emissions, energy intensity, share of renewable energy in suppl

Separating predictive responses from reactive responses in isochronous finger tapping using Bayesian hierarchical modeling

Finger tapping to isochronous pacing stimuli is a well established experimental paradigm first described in the late 19th century. Two variables of common interest in rhythmic tapping tasks are timing variability and constant error. However, a difficulty when estimating these variables is that at interstimulus intervals longer than 2 seconds participants regularly overshoot the target interval and

Towards scalable information modeling of requirements architectures

The amount of data in large-scale software engineering contexts continues to grow and challenges efficiency of software engineering efforts. At the same time, information related to requirements plays a vital role in the success of software products and projects. To face the current challenges in software engineering information management, software companies need to reconsider the current models

Risk Analysis for Critical Systems with Reliability Block Diagrams

Governmental organisations are becoming more critically dependant on IT systems such as communication systems or patient data systems, both for their everyday tasks and their role in crisis relief activities. Therefore it is important for the organisation to analyse the reliability of these systems as part of the organisation’s risk and vulnerability analysis process. This paper presents a practic

Surface Sampling and Automated Liquid Membrane Extraction of Fungicides

A number of approaches for fungicide determination are presented. A surface sampling technique is utilised for the determination of fungicide foliar residues on greenhouse surfaces, mainly leaves. The procedure is based on solvation of the fungicides on the leaf surface with ethanol and HPLC analysis. It was applied to studies of the environment in greenhouses including investigations of decline r