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Chronic lung diseases (CLDs), such as chronic obstructive pulmonary disease, interstitial lung disease, and lung cancer, are among the leading causes of morbidity globally and impose major health and financial burdens on patients and society. Effective treatments are scarce, and relevant human model systems to effectively study CLD pathomechanisms and thus discover and validate potential new targe
BACKGROUND: A slight increase in revisions for infected joint arthroplasties has been observed in the Nordic countries since 2000 for which the reasons are unclear. However, in 2007 a Swedish study of the timing for prophylactic antibiotics in a random sample of knee arthroplasties found that only 57% of the patients had received the antibiotic during the optimal time interval 45-15 minutes before
The aging of us humans is individual and occurs gradually over a long period of time. Some functions in the body deteriorate and older people often have difficulty for various reasons to get the amount of nutrition they need, so they usually need to divide their diet into more meals distributed during the day. In this essay, the diet served in a retirement home in a small municipality in northwest
Despite available training in food safety, regular inspections from the authorities and strict laws and regulations, the number of suspected food poisoning is estimated at 500,000 cases per year in Sweden (Norling, 1994). Since the 1990s, there have been discussions about introducing a "mandatory food driver's license" to improve food safety in Sweden. But no such license exists toda
Syftet med denna uppsats är att öka förståelsen för huvudintressenternas uppfattningar i Sverige kring den obligatoriska byrårotationen med hänsyn till oberoende och revisionskvalitet. Resultatet visar att majoriteten av huvudintressenterna är negativt inställda till den obligatoriska byrårotationen, speciellt i sin slutgiltiga utformning som troligtvis kommer vara utan påverkan på varken det fakt
Världen förändras kontinuerligt. Företag arbetar idag hårt för att hålla jämna steg med omvärlden för att på så vis hålla sig konkurrenskraftiga. Att arbeta för att hitta nya affärsmöjligheter har blivit av allt större betydelse. IKEA är ett globalt företag som står inför en enorm tillväxt för att nå deras mål till år 2020. För att klara denna tillväxt och för att kunna säkra försörjningen till nyThe world is continuously changing. Today many companies work hard to keep up with the surrounding world to stay competitive. To work with finding new business opportunities has become of higher importance than ever. IKEA is a global company facing a tremendous growth to reach their goal for 2020. To manage this growth and be able to secure supply to new retail markets, the company needs to increa
Background: Omni-channel retailing has led to customers becoming more demanding and less tolerant than before. For instance, customers are demanding shorter delivery times, and higher precision in deliveries. Unless retailers adapt to an omni-channel approach today, their business is likely to suffer. To do so, more efficient planning of the supply chain is necessary. The first step of the plannin
In the European Union the Annexes of its chemical legislation (REACH) were revised and now clarify the technical data requirements for nanomaterials (NMs). These new provisions, effective from January 1, 2020, introduce requirements for manufacturers, importers and downstream users regarding registration and safety assessment of NMs. This study aims to assess the availability and suitability of me
The use of 3D city models is changing from visualization to complex use cases where they act as 3D base maps. This requires links to registers and continuous updating of the city models. Still, most models never change or are recreated instead of updated. This study identifies obstacles to version management of 3D city models and proposes recommendations to overcome them, with a main focus on the
Spatially-distributed values of glacier aerodynamic roughness (z0) are vital for robust estimates of turbulent energy fluxes and ice and snow melt. Microtopographic data allow rapid estimates of z0 over discrete plot-scale areas, but are sensitive to data scale and resolution. Here, we use an extensive multi-scale dataset from Hintereisferner, Austria, to develop a correction factor to derive z0 v
Background Triptolide is an active natural product, which inhibits cell proliferation, induces cell apoptosis, suppresses tumor metastasis and improves the effect of other therapeutic treatments in several cancer cell lines by affecting multiple molecules and signaling pathways, such as caspases, heat-shock proteins, DNA damage and NF-ĸB. Purpose We investigated the effect of triptolide towards NF
A g-C3N4/CdSe quantum dot/[Fe2S2(CO)6] composite has been successfully constructed. The structure and chemical composition of the composite were investigated via, inter alia, transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). The ability of the assembly to act as a photocatalyst for proton reduction to form hydrogen g
Summary: The Fracture Liaison Service (FLS) Consensus Meeting endorsed by the International Osteoporosis Foundation (IOF), Asian Federation of Osteoporosis Societies (AFOS), and Asia Pacific Osteoporosis Foundation (APOF) was hosted by the Taiwanese Osteoporosis Association on October 14, 2017. International and domestic experts reviewed the 13 Best Practice Framework (BPF) standards and concluded
Growing globalisation and climate change are challenging the sustainability of our societies. It is now clear that climate change and its devastating impacts cannot be resolved by new technology or governance alone. They require a broader, cultural shift. As a result, the role of human beings' ‘inner dimensions’ and related transformations is attracting increased attention from researchers. Recent
BACKGROUND: The Self-Reported Foot and Ankle Score (SEFAS) is a foot- and ankle-specific patient-reported outcome measurement (PROM) score that has been validated with good results for a variety of foot and ankle disorders. SEFAS is sensitive detecting improvement or deterioration after surgery. However, normative values, required to put a specific patient's summary score into perspective, are lac
Societal safety and sustainability are key challenges in our complex and dynamic world, causing growth in interest of applying the concept of resilience in broader societal contexts. This chapter presents a concept of societal resilience that builds on established theory of Resilience Engineering and operationalises the concept by presenting its purpose, required functions and a way to identify an
This data article presents water stage, flow, and net primary productivity (NPP) data that were used to analyze the dynamics of the riverine dissolved organic carbon (DOC) dynamics in the Rukarara River watershed in Rwanda. We measured water stage data every 15 min and calculated daily averages used to estimate flow based on rating curves. The rating curves were produced using several measured con
The production of fast pyrolysis bio-oil (FPBO) from secondary biomass is a promising technique for the production of liquid biofuels. However, the resulting FPBO is often viscous and chemically unstable, requiring significant upgrading while also being difficult to work with. To overcome this issue, FPBO can be hydrotreated using slurry hydrotreatment, which has a long history as a processing tec
This study explores the effectiveness of combining Electrical Resistivity Tomography (ERT) and Induced Polarization (IP) for identifying internal erosion processes in embankment dams. A small-scale test dam was built in Älvkarleby, Sweden, with deliberately embedded but undisclosed defects to test monitoring capabilities. Daily ERT and IP measurements were collected during 4.5-year years, and anal
The sheet metal forming process is integral to the automotive industry, producing a variety of components essential for vehicle construction, including body panels, chassis parts, and structural supports. The process involves shaping thin metal sheets into desired forms using techniques such as bending, stretching, drawing, and stamping. In order to build high quality cars it is vital with an effi
