Filtyp
Background: While recent years have seen a revolution in the treatment of metastatic cutaneous melanoma, no treatment has yet been able to demonstrate any prolonged survival in metastatic uveal melanoma. Thus, metastatic uveal melanoma remains a disease with an urgent unmet medical need. Reports of treatment with immune checkpoint inhibitors have thus far been disappointing. Based on animal experi
Objective: To compare iron stores in infants born after elective caesarean section (CS) and a 30 s delay of umbilical cord clamping with those born vaginally after early (≤10 s) or delayed (≥180 s) cord clamping. Design: Prospective observational study with historical control. Setting: Swedish county hospital. Population: 64 infants born after elective CS were compared with a historical control of
Background: The exact pathophysiological mechanism(s) underlying endolymphatic hydrops (EH) remain elusive. We have previously shown that chronic administration of vasopressin and inhibitors of the cAMP/cGMP degrading enzymes (PDE3, PDE4, PDE5) results in the development of EH to mice. Aims/objectives: Evaluate the ability of spironolactone, an aldosterone antagonist, to prevent EH, when induced b
In order to simplify and/or improve determination of glomerular filtration rate (GFR) the clearances of iohexol, 51Cr-EDTA and endogenous creatinine were simultaneously determined with different techniques in 21 anesthetized landrace pigs. Their GFR had been reduced to about 1/3 or less of normal GFR. After an intravenous bolus of the GFR markers, their plasma concentration curves were followed fo
In epidemiologic studies on direct genetic associations, hypothesis testing is primarily considered for evaluating the effects of each candidate genetic marker, eg, single nucleotide polymorphisms. To help investigators protect themselves from over-interpreting statistically significant findings that are not likely to signify a true effect-a problem connected to multiple comparisons-consideration
Watchful waiting was recommended as an option for uncomplicated episodes of acute otitis media in Sweden in the year 2000. Concern was raised that these recommendations would lead to a higher incidence of acute mastoiditis. The aim of this study was to map the occurrence, treatment policy and the clinical course of mastoiditis before and after the new treatment recommendations were introduced. Inc
I argue that Lisa Shapiro’s rational reconstruction of Descartes’s provisional moral code in terms of a broad conception of morality supplies us with an interpretative framework that make historiographical sense of the reception of Descartes’s moral philosophy in an Anglophone context on three occasions: the appeal to Descartes made by Henry More, Henry Sidgwick’s abrupt dismissal, and the ensuing
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Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide, with ~40–50% of patients diagnosed with non-metastatic disease (stages IA–IIIC). The treatment landscape is evolving rapidly as immunotherapies and targeted therapy are introduced in the non-metastatic setting, creating a need to assess patient outcomes prior to their introduction. This real-world study usin
Background: Many patients with psychotic disorders have persistent paranoid ideation and avoid social situations because of suspiciousness and anxiety. We investigated the effects of virtual-reality-based cognitive behavioural therapy (VR-CBT) on paranoid thoughts and social participation. Methods: In this randomised controlled trial at seven Dutch mental health centres, outpatients aged 18–65 yea
To combat climate change, different types of initiatives and policy instruments are required to support the development and dissemination of new energy efficient technologies. What type of policy instruments shall be used is, however, not pre-determined. To advance knowledge in how to design successful policy instruments, evaluations and deep-analyses are needed; this to better understand the role
Cambodian migrants in the Thai construction sector, work in precarious working environments, with limited safety conditions and low wages. The use of social protection schemes has increased in recent decades, as a method of reducing the vulnerable against poverty and livelihood risks. However, despite the transformative potential of social protection, migrant workers face difficulties in accessing
This study employs an approach to policy as discourse and examines the construction of gender equality in the EU Gender Action Plan II. Drawing from the poststructural premise that discourses affect how issues are being thought about and acted upon, the study seeks to scrutinize how gender equality is attributed with meaning by applying Carol Bacchi’s analytical methodology What’s the problem repr
Corporations and in particular large multinational enterprises are important for every countries economic growth. However, exploitation and human rights abuses due to corporate activity are repeatedly occurring in states that lacks the proper legislation, enforcement or institutions to ensure human rights protection. Thus, there is an increasing call for lead firms of MNEs to exercise human rights
Schema MVEN05 Styrmedel för förebyggande miljöskydd VT2017 Läsning för lektionerna ges i modulbeskrivningarna Lokaler: Lokal på Internationella Miljöinstitutet (iiiee), se karta Datum och tid Aktivitet Lärare Lokal Modul I: Styrning och styrmedel 16 jan 10:15-15 (på Internationella miljöinstitutet) 17 jan 10-13 18 jan 10-13 20 jan 10-13 23-24 jan Kursintroduktion och föreläsning: miljöpolitiska st
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven05_prel._schema_vt17_v.2.pdf - 2026-07-16
