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We present novel coupling schemes for partitioned multiphysics simulation that combine four important aspects for strongly coupled problems: implicit coupling per time step, fast and robust acceleration of the corresponding iterative coupling, support for multirate time stepping, and higher-order convergence in time. To achieve this, we combine waveform relaxation—a known method to achieve higher-
The conflict between Armenia and Azerbaijan over Nagorno-Karabakh has put the Islamic regime of Iran in a difficult position. While the government is trying to be neutral, other regime elements have openly taken sides in the conflict.
Background: Postoperative pain clinical management in neonates has always been a challenging medical issue. Worldwide, several systemic opioid regimens are available for pediatricians, neonatologists, and general practitioners to control pain in neonates undergoing surgical procedures. However, the most effective and safe regimen is still unknown in the current body of literature. Objectives: To d
One of the core pathological features of Parkinson's disease (PD) is the loss of the dopaminergic nigrostriatal pathway which lies at the heart of many of the motor features of this condition as well as some of the cognitive problems. The importance of this pathological event is evident through the clinical benefits that are seen when patients with PD are treated with dopaminergic agents, at least
Artificial intelligence (AI) has been used to develop drug sensitivity prediction models, raising the opportunity of using it for personalized cancer medicine. This chapter describes recent advancements in drug response prediction methods using machine learning algorithms. Pharmacogenomic datasets come with different types of biological data including genetic mutations, gene expression, copy numbe
The metastatic potential of cancer cells is closely linked to their mechanical properties, and changes in these properties often correspond to the progression of the disease. To study how mechanical factors such as cell size and deformability influence the spread of cancer and the surrounding extracellular matrix, it is crucial that cancer cell populations be sorted in relevant subpopulations with
Time-frequency reassignment, commonly used to analyze time-varying signals, is a post-processing method that sharpens time-frequency representations. However, the reassignment method is sensitive to noise, making it unsuitable for time-frequency analysis when the signal-to-noise ratio is low. To increase the robustness of the reassignment technique, we develop a novel reassigned multitaper spectro
Developments in ambulatory electrocardiogram (ECG) technology have led to vast amounts of ECG data that currently need to be interpreted by human technicians. Here we tested an artificial intelligence (AI) algorithm for direct-to-physician reporting of ambulatory ECGs. Beat-by-beat annotation of 14,606 individual ambulatory ECG recordings (mean duration = 14 ± 10 days) was performed by certified E
In this article we aim to highlight the potential of forgotten grave materials in our museum depositories for gaining insights into prehistoric life. By applying a multi-proxy approach to the skeletal remains of two graves of uncertain types from Falbygden in western Sweden, we were able to acquire new knowledge of burial practices, subsistence, health and mobility in Late Neolithic and Early Bron
Attempts to use colloid science concepts to better understand the dynamic properties of concentrated or crowded protein solutions are challenging due to the fact that globular proteins generally have heterogeneous surfaces that result in anisotropic or patchy contributions to their interaction potential. This is particularly difficult when targeting non-equilibrium transitions such as glass and ge
Background Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion has not been well studied. Methods We randomly assigned, in a 1:1 ratio, patients who had taken factor Xa inhibitors within 15 hours before having an a
Immunotherapy can lead to long-term survival for some cancer patients, yet generalized success has been hampered by insufficient antigen presentation and exclusion of immunogenic cells from the tumor microenvironment. Here, we developed an approach to reprogram tumor cells in vivo by adenoviral delivery of the transcription factors PU.1, IRF8, and BATF3, which enabled them to present antigens as t
Mental health issues differ widely among individuals, with varied signs and symptoms. Recently, language-based assessments have shown promise in capturing this diversity, but they require a substantial sample of words per person for accuracy. This work introduces the task of Adaptive Language-Based Assessment (ALBA), which involves adaptively ordering questions while also scoring an individual’s l
DRAFT Irrigation management in conventional and organic potato production – A case study on the East Anglia region UK, working towards a sustainable future Vivianne Aggestam - 2 - Abstract The production of the potato crop in the UK is one of the most irrigated crops. This leads to serious pressure on water resources during the summer months, when water is the least available. The East Anglia regi
https://www.lumes.lu.se/sites/lumes.lu.se/files/vivianne_aggestam.pdf - 2026-06-24
This study introduces an efficient workflow for functional data analysis in classification problems, utilizing advanced orthogonal spline bases. The methodology is based on the flexible Splinets package, featuring a novel spline representation designed for enhanced data efficiency. The focus here is to show that the novel features make the package a powerful and efficient tool for advanced functio
Litteraturlista MULE23 VT26 Sida 1 av 2 Beslutad i Musikhögskolans Grundutbildningsnämnd 2025-11-05 Litteraturlista – MULE23 Lärande och ledarskap i skolan Bamford, Anne. (Gäst). (2022, 30 november). Framtidsförmågor i fokus genom kultur. [Poddsändning]. I Podagog Malmö. Pedagog Malmö, Malmö stad. https://pedagog.malmo.se/poddar/anne-bamford-om-att-arbeta-med- kultur-i-skolan/ Borgström Källén, Ca
https://www.mhm.lu.se/sites/mhm.lu.se/files/2025-12/Litteraturlista%20MULE23%20VT26.pdf - 2026-06-24
Saab Kockums AB has been tasked by the Swedish Armed Forces to develop a new submarine model named A26. This task poses many challenges, one of which being the design of the fire protection on the submarine. Few spaces are as closed to its surroundings as a submarine, and as consequence little research has been done to study FDS predictions of fire processes in these types of environments. The fo
