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Tropomyosin-related kinase A (TrkA) receptor mediates the effects exerted by nerve growth factor on several subpopulations of neuronal cells. Ligand binding to TrkA induces receptor autophosphorylation on several tyrosine residues and the activation of signaling cascades. In this study, we describe a new site relevant for TrkA regulation, the tyrosine 701 (Y701), which is important for receptor tr

Exercise is considered to be a "medicine" due to its modulatory roles in metabolic disorders such as diabetes and obesity. The intensity and duration of exercise determine the mechanism of energy production by various tissues of the body, especially by muscles, in which the requirement for adenosine triphosphate (ATP) increases by as much as 100-fold. Naturally, athletes try to improve their exerc

Local commercial fishing is often claimed to attract tourists to coastal communities. We investigate the impact of local fishing on tourism demand, measured as overnight stays, in Sweden. Using municipal-level data for the period 1998–2015, we perform a quantitative analysis using ordinary least squares (OLS) as well as panel-data methods that take unobserved heterogeneity between municipalities i

Women with breast cancer and micrometastases only constitute a treatment dilemma. If only a micrometastasis is found in a sentinel lymph node, an axillary lymph node dissection may be considered to be overtreatment and perhaps could be avoided. However, studies have shown decreased survival in patients with micrometastases only. This paper focuses on the pathological work-up behind the classificat

Following the line of the former Iron Curtain, the European Green Belt links protected areas across 24 countries, and restores key wildlife populations, wetlands and rural livelihoods. Its success proves that rewilding-grounded nature-based solutions can transform war-scarred frontiers into biodiversity-rich, climate-resilient lifelines, and challenges policymakers to replicate such mega-corridors

In this paper, we examine factors affecting owners’ intention for renovation of their detached houses. Furthermore, we analyze their interest in choosing a one-stop-shop (OSS) service for the renovation, even though such a concept is not yet established in Sweden, but emerging in other parts of Europe. Our study is based on responses to an online questionnaire survey of 971 house owners residing i

Due to social and environmental crises, the concept of sustainability has grown in importance in our society over the past years. Things are changing, even in the financial industry. From the perspective of investors, the general public, and enterprises, Corporate Social Responsibility and the creation of sustainable value are becoming more and more significant. One of the most cutting-edge tools

At present, coconut proteins are discarded as a waste product by the coconut oil industry. If the range of applications of coconut proteins is to be expanded, their potential functionalities should be investigated. Emulsions and gels are of the greatest interest in food industry. Today the dry processing of copra at elevated temperatures is used to optimize the oil recovery. The functionalities o

The purpose of the paper is to develop a framework of management competences related to the effective management of three types of online innovation tools. The framework highlights the development of three types of management competences and related practices: (a) disclosure competence in order to find, direct and motivate users to contribute, (b) appropriation competence in order to appropriate u

In laser-wakefield acceleration (LWFA), a femtosecond laser pulse is tightly focused in a gas to intensities exceeding 1018 W/cm2 . The laser radiation ionizes the medium and excites a plasma wave that travels behind the laser pulse. Electrons can be trapped in the oscillations in the plasma density, where electric fields of the order of several hundreds of GV/m accelerate them to relativistic ene

Coincidence and time-of-flight measurement techniques are employed to tag fission neutrons emitted from a 252Cf source sealed on one side with a very thin layer of Au. The source is positioned within a gaseous 4He scintillator detector. Together with α particles, both light and heavy fission fragments pass through the thin layer of Au and are detected. The fragments enable the corresponding fissio

A tabletop high-brightness line-emitting laser-plasma soft xray source utilizing single microscopic droplets as target is shown to produce several orders of magnitude less debris than conventional-target sources. Quantitative measurements of debris deposition rates and x-ray flux, at different directions around the droplet plasma are presented. With ethanol droplets and a. 10 Hz. 70 mJ/pulse laser

The discovery of collective effects in small collision systems has spurred a renewed interest in hadronization models, and is also a source for collective effects all the way to large collision systems, where they are usually ascribed to the creation of a Quark–Gluon Plasma. In this topical mini-review, the microscopic model for string interactions, based on the Lund string hadronization model, de

The aim of this project was to measure the profile of the radiation exiting an aperture of the Aquarium at the Source Testing Facility at the Division of Nuclear Physics at Lund University. So far, the outgoing beam of radiation at the aperture of the Aquarium has been assumed to be uniform. The radiation is produced by a Beryllium-based radioactive source and comes in the form of neutrons and γ-r