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Avd. bedriver grundforskning inom mikrobiologi, immunologi och glykobiologi, samt överbryggande forskning med klinisk inriktning. Molekylär bakteriell patogenes avser de mekanismer bakterier använder för att orsaka sjukdom med särskilt fokus kring infektioner i luftvägar, magtarmkanal, urinvägar och hud. Patogenerna orsakar intrikata cellbiologiska effekter. Den immunologiska forskningen inom avd.
Bacterial infections spanning from local wound infections, affecting patients with non-healing leg ulcers, postoperative wounds or burns, to severe infections and sepsis, are significant medical problems. Today's anti-infective treatments do not address the excessive activation of inflammatory pathways during infection and sepsis, and resistance problems are increasing. Hence, there is a huge unmBacterial infections spanning from local wound infections, affecting patients with non-healing leg ulcers, postoperative wounds or burns, to severe infections and sepsis, are significant medical problems. Today's anti-infective treatments do not address the excessive activation of inflammatory pathways during infection and sepsis, and resistance problems are increasing. Hence, there is a huge unm
Forskarna inom detta område arbetar med forskning om bruk, skadligt bruk och beroende av alkohol och andra droger, ofta ur ett socialvetenskapligt perspektiv. Även beroendeproblem kopplade till spel om pengar och dopning berörs. Forskningen rör såväl människors livsvillkor och erfarenheter som vårdens, socialtjänstens och andra samhällsaktörers arbete. Forskningen har en bred metodologisk ansats oResearchers in this area study the use, harmful use, and dependence on alcohol and other drugs, often from a social science perspective. Gambling-related addiction problems and doping are also included. The research addresses both people’s living conditions and experiences, and the work of healthcare services, social services, and other societal actors. It takes a broad methodological approach and
Introduction: Complicated perianal disease (cPD) may be the sole presentation of Crohn’s disease (CD). The role of small-bowel capsule endoscopy (SBCE) in the diagnostic algorithm of cPD is unclear. We aimed to evaluate the role of SBCE as a diagnostic tool, in patients with cPD, after a negative standard workup for CD. Methods: A multicenter, retrospective, cross-sectional study, in patients with
IMPORTANCE: Atrial fibrillation (AF), the most prevalent sustained arrhythmia, portends higher risk of cardiovascular morbidity and mortality, and is associated with quantifiable impairment in quality of life. While physical activity is widely recognized for its cardiovascular benefits, recent evidence challenges its role in the development of AF. OBSERVATIONS: Emerging data suggest a U-shaped rel
This paper aims to explore how learning about Circular Economy (CE) may be facilitated through the use of the serious game In the Loop. Despite the growing literature base related to CE, academic reflection on education for a CE is currently limited. In the Loop was developed to provide an experiential learning situation for educating about material criticality and CE. This study reflects on the u
Gruppen driver forskning kring mätning och behandling av svår kronisk andnöd (dyspné) samt behandling av kronisk andningssvikt. Gruppen har nära samarbete med ledande forskare nationellt och ett internationellt forskningsnätverk kring klinisk dyspnéforskning. Studier inkluderar epidemiologiska analyser, Cochrane meta-analyser, kliniska kohortstudier samt randomiserade kontrollerade behandlingsstudThe research group focuses on the mechanisms, measurement and treatment of severe chronic breathlessness (dyspnea) and management of chronic respiratory failure. The research is conducted in close collaboration with leading researchers nationally and an international research network. Studies include epidemiological analyses, Cochrane meta-analyses, clinical cohorts and randomized controlled trial
Enheten för psykiatrisk epidemiologi och folkhälsa studerar ämnesområden som exempelvis psykossjukdomar, suicidologi, beroendetillstånd och neuropsykiatriska tillstånd med klassiska och moderna epidemiologiska metoder. Dessa frågor belyses dels utifrån ett kliniskt perspektiv med traditionella frågeställningar gällande riskfaktorer, utfall, överlevnad och farmakoepidemiologi, dels utifrån ett folkThe Unit for Psychiatric Epidemiology and Public Health studies subject areas such as psychotic disorders, suicidology, substance use disorders, and neuropsychiatric conditions using classical and modern epidemiological methods. These issues are examined both from a clinical perspective, with traditional research questions regarding risk factors, outcomes, survival, and pharmacoepidemiology, and f
