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Secretion and Dipeptidyl Peptidase-4-Mediated Metabolism of Incretin Hormones after a Mixed Meal or Glucose Ingestion in Obese Compared to Lean, Nondiabetic Men.

Context: Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are cleaved by dipeptidyl peptidase-4 (DPP-4); plasma activity of DPP-4 may be increased in obesity. The impact of this increase on incretin hormone secretion and metabolism is not known. Objective: The aim of the study was to assess incretin hormone secretion and degradation in lean and obese nondiabet

Injury markers predict time to dementia in subjects with MCI and amyloid pathology.

OBJECTIVES: Alzheimer disease (AD) can now be diagnosed in subjects with mild cognitive impairment (MCI) using biomarkers. However, little is known about the rate of decline in those subjects. In this cohort study, we aimed to assess the conversion rate to dementia and identify prognostic markers in subjects with MCI and evidence of amyloid pathology. METHODS: We pooled subjects from the VU Un

Short-term effects of a pay-for-performance programme for diabetes in a primary care setting: an observational study

Objective A pay-for-performance (P4P) programme for primary care was introduced in 2011 by a Swedish county (with 1.6 million inhabitants). Effects on register entry practice and comparability of data for patients with diabetes mellitus were assessed. Design and setting Observational study analysing short-term outcomes before and after introduction of a P4P programme in the study county as compare

Moderate intensity supine exercise causes decreased cardiac volumes and increased outer volume variations: a cardiovascular magnetic resonance study

Background: The effects on left and right ventricular (LV, RV) volumes during physical exercise remains controversial. Furthermore, no previous study has investigated the effects of exercise on longitudinal contribution to stroke volume (SV) and the outer volume variation of the heart. The aim of this study was to determine if LV, RV and total heart volumes (THV) as well as cardiac pumping mechani

Profile of intraocular tumour necrosis factor-α and interleukin-6 in diabetic subjects with different degrees of diabetic retinopathy.

Purpose: To assess and correlate the levels of inflammatory mediators in the eyes from non-diabetic and diabetic subjects without retinopathy (NDR), with non-proliferative diabetic retinopathy (NPDR) or with proliferative diabetic retinopathy (PDR) to corresponding erum levels. Methods: The levels of interleukin 1β, interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) were analysed by an EL

Oncoretroviral gene transfer to NOD/SCID repopulating cells using three different viral envelopes

Background The aim of this study was to investigate gene transfer to human umbilical cord blood (CB) CD34(+)/CD38(low) and NOD/SCID repopulating cells using oncoretroviral vectors and to compare the transduction efficiency using three different viral envelopes. Methods CB cells were transduced on Retronectin using an MSCV-based vector with the gene for GFP (MGIN), which was packaged into three dif

Design and dosimetry characteristics of a soft-docking system for intraoperative radiation therapy

PURPOSE: The design concept and the dosimetric characteristics of an applicator system for intraoperative radiation therapy (IORT) with special emphasis on alignment methods, the effect of a plastic scatterer in the beam, radiation leakage, and misalignment dosimetry, are presented in this paper. MATERIALS AND METHODS: A soft-docking system for a linear accelerator, which enables collimation of el

NORdic trial of oral Methylprednisolone as add-on therapy to Interferon beta-1a for treatment of relapsing-remitting Multiple Sclerosis (NORMIMS study): a randomised, placebo-controlled trial

Background Treatment of relapsing-remitting multiple sclerosis with interferon beta is only partly effective, and new more effective and safe strategies are needed. Our aim was to assess the efficacy of oral methylprednisolone as an add-on therapy to subcutaneous interferon beta-1a to reduce the yearly relapse rate in patients with relapsing-remitting multiple sclerosis. Methods NORMIMS (NORdic tr

Direct electrochemistry of recombinant tobacco peroxidase on gold

Direct electron transfer (DET) reactions of recombinant tobacco peroxidase (rTOP), namely direct electroreduction of Compound I/ Compound II and heme Fe3+/2+ conversion, were studied on gold electrodes. rTOP of wild type, non-glycosylated, was produced using, an Escherichia coli expression system. At pH 5.0, the redox potential for direct electrochemical transformation of the Fe3+/2+ of the peroxi

The apolipoprotein E epsilon4 allele frequency is normal in fronto-temporal dementia, but correlates with age at onset of disease

The apolipoprotein (apoE) epsilon4 allele was studied in fronto-temporal dementia (FTD), a diagnostic category including the specific disorders Pick's disease and frontal lobe degeneration of non-Alzheimer type (FLD). These dementing diseases have neuronal and synaptic degeneration in common with Alzheimer's disease (AD), for which the presence of the apoE epsilon4 allele is a known risk factor, a

Sustainability and EU Migration Law : What Place for Migrants' Rights?

Sustainable migration is the new objective of EU migration law, a term whose meaning and legal implications are unclear. Through a critical historical study of different areas of EU migration law, this book explores whether and how the past can guide the way for a contemporary understanding of sustainable migration, and it reveals the potentials and limits of this novel objective.

Methotrexate treatment in early psoriatic arthritis in comparison to rheumatoid arthritis : an observational nationwide study

Introduction We aimed to compare the proportions of patients with newly diagnosed psoriatic arthritis (PsA) and rheumatoid arthritis (RA) remaining on methotrexate (regardless of other disease-modifying antirheumatic drug (DMARD)-changes), and proportions not having started another DMARD (regardless of methotrexate discontinuation), within 2 years of starting methotrexate, as well as methotrexate

Nationella forskarkurser - media-geographies 2017

Namnlös 2016-11-04 Media Geographies (National PhD Course in, Fall semester 2017, 7.5 ECTS) Course organizers: Mekonnen Tesfahuney, Professor, Department of Geography, Media & Communication Karlstad University (mete@kau.se) Richard Ek, Associate Professor, Institute of Service Management, Lunds University (richard.ek@ism.lu.se) André Jansson, Professor, Department of Geography, Media & Communicati

https://www.keg.lu.se/sites/keg.lu.se/files/nationella_forskarkurser_-_media-geographies_2017.pdf - 2026-06-07

Inledningskapitel Ändrade Förhållanden 1

Introduktion Ola Svensson, Johan Axhamn och Birgitta Nyström 1 Ändrade förhållanden – ett aktuellt ämne Denna bok är inspirerad av ett projekt om ändrade förhållanden inom kontraktsrätten initierat av ämnesgruppen för avtalsrätt och obligations- rätt inom ACLU, Affärsrättsligt centrum vid Lunds universitet. Boken kan ses som ett led i ett pågående arbete.1 I en avtalssituation kan förhållandena än

https://www.aclu.lu.se/en/sites/aclu.lu.se.en/files/2023-04/Inledningskapitel%20A%CC%88ndrade%20fo%CC%88rha%CC%8Allanden_1.pdf - 2026-06-07

SIMM34 FINAL 210212

SIMM34 FINAL 210212 1 GRADUATE SCHOOL METHODS COURSES SIMM34 Digital Media Research Version 1.0 – Oktober 2020 SPRING 2021 2 1. WELCOME SIMM34 DIGITAL MEDIA RESEARCH Contact info Graduate School e-mail: master@sam.lu.se Home page: graduateschool.sam.lu.se Facebook: tinyurl.com/LUgradschoolFB Student Union Home page: samvetet.org Lund University Home page: http://lunduniversity.lu.se The university

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2021-03/SIMM34%20FINAL%20210212.pdf - 2026-06-07

Food diversity estonia-russia article marcella samuels 20160320 final 0

Food Diversity Estonia-Russia article_Marcella Samuels_20160320_final   1   FoodDiversity Pre-Study outreach efforts connect innovative communities as Rural Living Labs for food security Study visits to Estonia and Russia continue to broaden Baltic Sea Region network of small-scale food producers striving for food security By Marcella Samuels The FoodDiversity Pre-Study Project international conso

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/food_diversity_estonia-russia_article_marcella_samuels_20160320_final_0.pdf - 2026-06-07

Entanglement in nano systems

This bachelor thesis on entanglement in nano systems includes a short presen-tation of the history of quantum mechanics before entanglement takes the spot light. A definition of entanglement will be stated as well as a prescription to quantify it for a pure system. The knowledge will then be used to quantify the entanglement for the ground state of few particle systems containing 2, 3 and 4 particl