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Introduction: Mitochondrial dysfunction has been suggested as a contributing factor to the pathogenesis of sepsis-induced multiple organ failure. Also, restoration of mitochondrial function, known as mitochondrial biogenesis, has been implicated as a key factor for the recovery of organ function in patients with sepsis. Here we investigated temporal changes in platelet mitochondrial respiratory fu
Measuring intima-media thickness (IMT) in the common carotid artery (CCA) is a valuable resource for the evaluation of subclinical atherosclerosis. The main objective of this study was to explore whether a B-mode ultrasound technique, Philips ATL, and an M-mode ultrasound technique, Wall Track System (WTS), show interchangeable results when measured in CCA and the abdominal aorta (AA). A total of
Background:Membranous expression of the anti-adhesive glycoprotein podocalyxin-like (PODXL) has previously been found to correlate with poor prognosis in several major cancer forms. Here we examined the prognostic impact of PODXL expression in urothelial bladder cancer.Methods:Immunohistochemical PODXL expression was examined in tissue microarrays with tumours from two independent cohorts of patie
Graft-induced dyskinesia (GID) is a serious complication induced by dopamine (DA) cell transplantation in parkinsonian patients. We have recently shown that DA D2 receptor blockade produces sticking blockade of dyskinesia induced by amphetamine in grafted 6-OHDA-lesioned rats, a model of GID. This study was designed to investigate whether blockade of DA D1 receptors could produce similar outcome,
Reduced forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) have been associated with increased incidence of cardiovascular diseases. However, whether reduced lung function is also a risk factor for incidence of atrial fibrillation (AF) is still unclear. We aimed to determine whether lung function predicted AF in the Malmö Preventive Project, a large population-based coho
Adrenomodulin (ADM) is a peptide hormone secreted in response to cellular strain such as ischemia and is believed to have a beneficial effect on the cardiovascular system. However, the epidemiological relationships between ADM and measurements of haemodynamics, arteriosclerosis and atherosclerosis are not well established. The aim of this study was to investigate the association between the mid-re
Evidence from clinic-based studies suggests that the fibromyalgia syndrome (FMS) is associated with impairment in cognitive function though the mechanism is unclear. The aim of this analysis was to determine whether there is a similar association between chronic widespread pain (CWP), a cardinal feature of FMS, and impaired cognition in a community setting. Men (n = 3369, 40-79 years) were recruit
AimsWe aimed to investigate the association between the exercise systolic blood pressure (SBP) response and future hypertension (HTN) in normotensive individuals referred for cycle ergometry, with special regard to reference exercise SBP values and exercise capacity.Methods and resultsIn this longitudinal cohort study, data from 14 428 exercise tests were cross-linked with Swedish national registr
Background: Intraspecific communication is of crucial importance throughout the animal kingdom and may involve a combination of visual, gustatory, olfactory and acoustic cues. Variation in male sex pheromone amount and composition may convey important information to female conspecifics, for instance on species identity or age. However, whether increased male pheromone titres are associated with fi
The number of international students in higher education is steadily increasing, so their experiences in the new environment is a topic gaining more and more interest from academics (Wu & Hammond, 2011). The current research suggests a model for determining international students’ happiness. The determining factors in the hypothesized model are university satisfaction, residential satisfaction
Denna uppsats undersöker de levda erfarenheterna hos japanska migranter i Sverige, en grupp som omfattar cirka 4 600 individer, varav nästan 80 procent har valt att permanent bosätta sig i Sverige. De återstående 20 procenten är tillfälliga invånare, som studenter, forskare eller utstationerade chefer, verksamma i något av de cirka 200 japanskägda företagen i landet. Till skillnad från andra europThis thesis explores the lived experiences of Japanese migrants to Sweden, a demographic that includes approximately 4,600 individuals, of whom nearly 80 percent chose to settle permanently in Sweden. The remaining 20 percent are temporary residents, as students, researchers, or as expatriate managers, working in one of the roughly 200 Japanese-owned companies in the country. In contrast to other
I dagens samhälle ser vi diskussioner rörande klimatfrågor och jämställdhet både på samhälls- och individnivå. Dessa diskussioner engagerar och kan påverka allt ifrån stora aktörer till enskilda individer. Denna uppsats intresserar sig för hur dessa diskussioner samverkar när ett företag väger in båda frågorna vid marknadsföringsstrategier. Uppsatsen är en kvalitativ textanalys vars syfte är att u
This thesis contributes to leadership theory, specifically, full-range-leadership and VUCA, and the practical implications. Moreover, it addresses challenges that organizations may face when implementing these models in reality. We utilized an inductive research approach to identify insights within the leadership field in combination with a qualitative research method, grounded in interpretivism a
On January 1, 2022, the first requirement regarding climate declarations was introduced. This mandate specified that all new buildings must include climate declarations during the construction phase, encompassing modules A1-A5. In 2025, limit values are also planned to be added for the existing modules included in the 2022 climate declarations. These required values will be implemented as a signif
Smart grids are often advertised as more environmentally sustainable compared to their “conventional” counterparts. What is highlighted then is their potential to save energy and integrate more renewables into the grid, thus decreasing CO2-emissions. This thesis investigates two less discussed aspects of smart grids, those of circular economy and social sustainability. An initial literature review
