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Given a directed graph as input, we show how to efficiently find a shortest (directed, simple) cycle on an even number of vertices. As far as we know, no polynomial-time algorithm was previously known for this problem. In fact, finding any even cycle in a directed graph in polynomial time was open for more than two decades until Robertson, Seymour, and Thomas (Ann. of Math. (2) 1999) and, independ
Caffeine acts as a central nervous stimulant by blocking A1 and A2A adenosine receptors. Its effect on seizures is complex. Animal studies and case reports indicate that acute caffeine exposure may induce seizures, whereas chronic exposure might have an opposite effect. Patients acutely hospitalized for seizures (n=174) were asked for their consumption of caffeinated beverages 24. h prior to admis
The presence of overlapping elements in distinct events promotes the formation of associative inferences across event boundaries, thereby shaping how new information is integrated with pre-existing knowledge. This study investigates the influence of schema congruency on mnemonic processes involved in such associative inferences.The present study employed EEG recordings of brain activity to assess
A key issue in sexual selection theory is how a correlation between male secondary sexual characters and male genetic quality can be maintained. The immunocompetence-handicap hypothesis proposes that testosterone-dependent male characters remain honest signals because of the immunosuppressive effect of elevated steroid hormone levels. The hypothesis requires that physiological levels of testostero
In this paper, we explore cybersecurity from a sociotechnical work-system perspective and focus on the visibility and effectiveness of security practices as part of the everyday work practices of typical employees. The empirical inquiry involved 471 employees from 259 different organizations, drawn from both private and public sectors using semi-structured interviews and conducted from an interpre
A central role for sexual isolation in the formation of new species and establishment of species boundaries has been noticed since Darwin and is frequently emphasized in the modern literature on speciation. However, an objective evaluation of when and how sexual isolation plays a role in speciation has been carried out in few taxa. We discuss three approaches for assessing the importance of sexual
Metabolism plays a central role in evolution, as resource conservation is a selective pressure for fitness and survival.Resource-driven adaptations offer a good model to study evolutionary innovation more broadly. It remains unknown howresource-driven optimization of genome function integrates chromatin architecture with transcriptional phase transitions.Here we show that tuning of genome architec
There are plenty of books and articles on research methods, but few discuss the nature and purpose of method sections in academic journals. Based on interviews with critical and interpretivist researchers, this short paper examines the nature and purpose of method sections in management and organization studies. We show how researchers make sense of, and struggle with, positivist expectations abou
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In general, the word, photosynthesis, is considered synonymous with oxygenic photosynthesis, a process by which cyanobacteria, algae, aquatic, and terrestrial plants produce oxygen and carbohydrates, using light (photons), water and carbon dioxide. Further, we have anoxygenic bacterial photosynthesis where oxygen is not evolved, but a substrate, other than water, is oxidized, and rhodopsin-type sy
Cocaine and amphetamine-regulated transcript (CART) is expressed in pancreatic islet cells and neuronal elements. We have previously established insulinotropic actions of CART in human and rodent islets. The receptor for CART in the pancreatic beta cells is unidentified. We used RNA sequencing of Cartpt knockdown (KD) INS-1 832/13 cells and identified GPR162 as the most Cartpt-regulated receptor.
BACKGROUND: Several molecular classification systems for bladder cancer have been proposed, but due to differences on how to define molecular subtypes, controversies and misunderstandings have arisen. OBJECTIVE: To discuss different aspects of the molecular classification of bladder cancer and to point to the consequences of using different conceptual approaches. To question some underlying assump
Gaming as a Service is not defined in existing research. The lack of a formal definition leads to an ambiguity between its function as a business model and the long-term strategy of the firm. The purpose and aim of this study is to investigate the definition of GaaS business model, distinguishing its function from the strategy. Furthermore, the key components of the model are established based on
INTRODUCTION: Mental health service users often have sensory processing difficulties hampering their ability to cope with mental health problems and occupational engagement. However, there is little knowledge of sensory processing and its relation to these factors. Hence, this current study aims to investigate sensory processing patterns in relation to coping and occupational engagement for the ta
Medellivslängden för människor runt om i världen är högre än någonsin. Äldre personer löper högre risk för att drabbas av kroniska sjukdomar, inklusive kronisk njursjukdom. Patienter med dysfunktionella njurar behöver dialys. Njurarnas huvudfunktion är att rena blodet från restprodukter och överflödigt vatten. År 2018 hade Sverige 4101 dialyspatienter av vilka 1026 hade hemdialys. En dialyspatientThe average life expectancy for people around the world is higher than ever before. Older people are at higher risk of suffering from chronic diseases, including chronic kidney disease. Patients with dysfunctional kidneys need dialysis. The main function of the kidneys is to clean the blood from waste products and excess water. In 2018, Sweden had 4101 dialysis patients of which 1026 had home dial
