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The presence of overlapping elements in distinct events promotes the formation of associative inferences across event boundaries, thereby shaping how new information is integrated with pre-existing knowledge. This study investigates the influence of schema congruency on mnemonic processes involved in such associative inferences.The present study employed EEG recordings of brain activity to assess
A key issue in sexual selection theory is how a correlation between male secondary sexual characters and male genetic quality can be maintained. The immunocompetence-handicap hypothesis proposes that testosterone-dependent male characters remain honest signals because of the immunosuppressive effect of elevated steroid hormone levels. The hypothesis requires that physiological levels of testostero
Can AI ‘solve’ politics? In this paper, I explore optipolitics, i.e., the idea that politics along with other complex social issues can be framed as mathematical optimization problems and solved as such. I begin by describing politics, optimization, and some reasons for applying the latter to the former. I then present a liberal democratic version of optipolitics and try to defend it against eight
Artificially cultivated meat may have environmental benefits and harm-reductive capabilities, making it crucial to establishing ethical food production practices. However, we argue that salient factors make producing and consuming artificially cultivated meat morally problematic. We detail some of these factors and highlight their roots in different ethical traditions. These factors present seriou
Cocaine and amphetamine-regulated transcript (CART) is expressed in pancreatic islet cells and neuronal elements. We have previously established insulinotropic actions of CART in human and rodent islets. The receptor for CART in the pancreatic beta cells is unidentified. We used RNA sequencing of Cartpt knockdown (KD) INS-1 832/13 cells and identified GPR162 as the most Cartpt-regulated receptor.
BACKGROUND: Several molecular classification systems for bladder cancer have been proposed, but due to differences on how to define molecular subtypes, controversies and misunderstandings have arisen. OBJECTIVE: To discuss different aspects of the molecular classification of bladder cancer and to point to the consequences of using different conceptual approaches. To question some underlying assump
In this paper, we explore cybersecurity from a sociotechnical work-system perspective and focus on the visibility and effectiveness of security practices as part of the everyday work practices of typical employees. The empirical inquiry involved 471 employees from 259 different organizations, drawn from both private and public sectors using semi-structured interviews and conducted from an interpre
Medellivslängden för människor runt om i världen är högre än någonsin. Äldre personer löper högre risk för att drabbas av kroniska sjukdomar, inklusive kronisk njursjukdom. Patienter med dysfunktionella njurar behöver dialys. Njurarnas huvudfunktion är att rena blodet från restprodukter och överflödigt vatten. År 2018 hade Sverige 4101 dialyspatienter av vilka 1026 hade hemdialys. En dialyspatientThe average life expectancy for people around the world is higher than ever before. Older people are at higher risk of suffering from chronic diseases, including chronic kidney disease. Patients with dysfunctional kidneys need dialysis. The main function of the kidneys is to clean the blood from waste products and excess water. In 2018, Sweden had 4101 dialysis patients of which 1026 had home dial
The research takes a descriptive and exploratory approach in understanding how the risk experience of top athletes shapes sports entrepreneurs’ risk-handling strategies. In particular, the purpose of this study is to advance the theoretical knowledge of entrepreneurial risk-handling by studying risk-handling strategies developed and applied by sports entrepreneurs and putting them into a conceptua
Gaming as a Service is not defined in existing research. The lack of a formal definition leads to an ambiguity between its function as a business model and the long-term strategy of the firm. The purpose and aim of this study is to investigate the definition of GaaS business model, distinguishing its function from the strategy. Furthermore, the key components of the model are established based on
INTRODUCTION: Mental health service users often have sensory processing difficulties hampering their ability to cope with mental health problems and occupational engagement. However, there is little knowledge of sensory processing and its relation to these factors. Hence, this current study aims to investigate sensory processing patterns in relation to coping and occupational engagement for the ta
This paper is one in a series of experimental studies on the effects of food composition on aging and longevity, using the golden-haired blowfly Calliphora stygia as the animal model Here we examine how diet. fat content affects blowfly life history traits such as longevity, reproduction, feeding rate, body mass, total fat content and membrane fatty acid composition. The highest median and maximum
The tumor suppressor PTEN antagonizes phosphatidylinositol 3-kinase (PI3K), which contributes to tumorigenesis in many cancer types. While PTEN mutations occur in some melanomas, their precise mechanistic consequences have yet to be elucidated. We sought to identify novel downstream effectors of PI3K using a combination of genomic and functional tests. Microarray analysis of 53 melanoma cell lines
