Filtyp
α-Synuclein is a presynaptic protein associated to Parkinson's disease, which is unstructured when free in the cytoplasm and adopts α helical conformation when bound to vesicles. After decades of intense studies, α-Synuclein physiology is still difficult to clear up due to its interaction with multiple partners and its involvement in a pletora of neuronal functions. Here, we looked at the remarkab
A new and freely available model-based PID design tool for Matlab is introduced. It can be used to solve Maximal Integral Gain Optimization (MIGO) and (load) Integral Absolute Error (IAE) problems. Robustness is ensured through H-inf constraints on the closed-loop transfer functions. A Youla parameter (Q design) method for comparison with the optimal linear time-invariant (LTI) controller for the
Group Exhibition. Hessel Museum, CCS Bard, New York. April 8th - May 27th
We show, through a combination of density function theory-based molecular dynamics simulations (DFT-MD) and experimental X-ray absorption fine structure spectroscopy (XAFS) studies, that the iodate ion (IO 3 -) contains a local region that is strongly hydrated as a cation. The local region adjoining the I atom is sufficiently electropositive that thr
The problem of estimating receiver or sender node positions from measured receiver-sender distances is a key issue in different applications such as microphone array calibration, radio antenna array calibration, mapping and positioning using UWB or using round-trip-time measurements between mobile phones and WiFi-units. In this paper we address the problem of optimally estimating a receiver positi
Several earlier studies have assessed survival in breast cancer based on familial risk of this disease. The results have been conflicting and suggest that the risk and prognostic factors of cancer are largely distinct. As a novel concept, we searched for familial clustering of survival, i.e., concordance of survival among family members. We used the nation-wide Swedish Family-Cancer Database to es
Apelin, a recently discovered peptide with wide tissue distribution, regulates feeding behavior, improves glucose utilization, and inhibits insulin secretion. We examined whether apelin is expressed in human islets, as well as in normal and type 2 diabetic (T2D) animal islets. Further, we studied islet apelin regulation and the effect of apelin on insulin secretion. Apelin expression and regulatio
We present a solution for optimal triangulation in three views. The solution is guaranteed to find the optimal solution because it computes all the stationary points of the (maximum likelihood) objective function. Internally, the solution is found by computing roots of multivariate polynomial equations, directly solving the conditions for stationarity. The solver makes use of standard methods from
One does not have to be an ethical non-cognitivist to find that moral guidance sometimes is totally absent. The agent may be confronted by a new kind of problem, or he may feel that the rules presented are too unclear to give any guidance, or he may quite simply regard established morality as without foundation. 1. Total ignorance; 2. Synthesis; 3. Towards solution; 4. Universal validity; 5; Ethic
This paper focuses on the discussion of the general characteristics of 12 Swedish learners’ oral production of the Chinese aspect markers le, guò, zài, and zhe. Their oral performance is discussed with respect to Krashen’s Monitor hypothesis (1978, 1981, 1987) on the role of conscious learning. The functions of the Monitor in planning, editing and correcting is discussed respectively in relation t
Popular Abstract in Swedish Fjärrvärme är ett centraliserat uppvärmningssystem där varmt vatten distribueras i ett rörnätverk och används främst till byggnadsuppvärmning och för att värma varmvatten. Fjärrvärme finns i alla länder på norra halvklotet men har störst marknadsandel i Norden och Baltikum. I Sverige används fjärrvärme för att värma c:a 60% av all byggnadsyta. Två stora fördelar med fjäRenewable energy sources dominated the world energy supply until the beginning of the 20th century, when fossil energy became the dominant energy source worldwide. Today, fossil fuels contribute to over 80% of world energy supply. But there are two major reasons why fossil energy use has to stop. First, fossil energy is limited and will not last forever. Second, emissions of carbon dioxide change
