Sökresultat

Abstract is not available

China has ever since the 1990s emerged as a manufacturing superpower, following its liberalized trade reforms and its entrance to the World Trade Organization. This has caused China to expand their exports substantially, in particular to the OECD countries. This has lead to an increasing debate on whether, or to what extent, increasing manufacturing exports from China to the OECD countries has con

China has ever since the 1990s emerged as a manufacturing superpower, following its liberalized trade reforms and its entrance to the World Trade Organization. This has caused China to expand their exports substantially, in particular to the OECD countries. This has lead to an increasing debate on whether, or to what extent, increasing manufacturing exports from China to the OECD countries has con

The purpose with this project was to create future self-service points for Skånetrafiken. The ticket machines that are in use today are difficult to interact with and excluding to people who are sight impaired or uses a wheelchair. Since Skånetrafiken are going to implement new self-service solutions in 2019 they want suggestions on how it could be designed. We thought that this project was an exc

Although Parkinson's disease is a movement disorder, in many patients cognitive dysfunction is an important clinical sign. It is not yet clear whether this is attributable solely to a decrease in dopamine levels, or whether other neurotransmitter systems might be involved as well. In the present study, the importance of the mesocorticolimbic dopamine pathway and a possible convergence with forebra

TV-on-Demand service has become one of the most popular Internet applications that continuously attracts higher user interests. With rapidly increasing user demand, the existing network conditions may not be able to ensure low start-up delay of video playback. Prefetching has been broadly investigated to cope with the start-up latency problem which is also known as user perceived latency. In this

Distributed e-Infrastructure is a key component of modern BIG Science. Service discovery in e-Science environments, such as Worldwide LHC Computing Grid (WLCG), is a crucial functionality that relies on service registry. In this paper we re-formulate the requirements for the service endpoint registry based on our more than 10 years experience with many systems designed or used within the WLCG e-In

Due to social and environmental crises, the concept of sustainability has grown in importance in our society over the past years. Things are changing, even in the financial industry. From the perspective of investors, the general public, and enterprises, Corporate Social Responsibility and the creation of sustainable value are becoming more and more significant. One of the most cutting-edge tools

Purpose: The purpose of this paper is to shed light on which role authenticity plays in mobile dating apps, an environment where users can present themselves only with a limited amount of information. By investigating how users create their profiles and evaluate others, the existing knowledge on authenticity and self-presentation can be advanced. Methodology: The research applied a relativist and

The kinin B1 receptor (B1R) is a G protein-coupled receptor with pro-inflammatory activity that is latent in healthy tissues but induced by tissue insult. Here, we investigated if B1R homo-oligomerization is a possible mechanism regulating the presentation of this receptor at the level of maturation and trafficking to the cell surface. To this end, we used HEK293 cells stably expressing N-terminal

Transforming growth factor-beta (TGF-beta) is involved in vascular formation through activin receptor-like kinase (ALK)1 and ALK5. ALK5, which is expressed ubiquitously, phosphorylates Smad2 and Smad3, whereas endothelial cell (EC)-specific ALK1 activates Smad1 and Smad5. Because ALK5 kinase activity is required for ALK1 to transduce TGF-beta signaling via Smad1/5 in ECs, ALK5 knockout (KO) mice w

We have previously shown that protein kinase Cepsilon (PKCepsilon) induces neurite outgrowth via its regulatory domain and independently of its kinase activity. This study aimed at identifying mechanisms regulating PKCepsilon-mediated neurite induction. We show an increased association of PKCepsilon to the cytoskeleton during neuronal differentiation. Furthermore, neurite induction by overexpressi

The aggregating proteoglycans (aggrecan, versican, neurocan, and brevican) are important components of many extracellular matrices. Their N-terminal globular domain binds to hyaluronan, but the function of their C-terminal region containing a C-type lectin domain is less clear. We now report that a 90-kDa protein copurifies with recombinant lectin domains from aggrecan and versican, but not from t

Previous studies have demonstrated that in admixed populations, West African ancestry is associated with an increased prevalence of systemic lupus erythematosus (SLE). In the current study, the effect of Amerindian ancestry in SLE was examined in an admixed population in Argentina. The Argentine population is predominantly European with approximately 20% Amerindian admixture, and a very small (<2%