Filtyp
The base of the world economic pyramid, generally called the base of the pyramid (BoP), consists of four billion people with average per day income of four dollars. While some authors suggest a systems approach to design and develop products and services (i.e. interventions) for BoP markets, a little work has been carried out in this area. Furthermore, a framework to represent interventions in the
Glyoxal (CHOCHO), as an indicator of photochemical “hot spots”, was for the first time the subject of a differential absorption lidar (DIAL) campaign. The strongest absorption line of glyoxal in the blue wavelength region – 455.1 nm – was chosen as the experimental absorption wavelength. In order to handle the effects of absorption cross-section variation of the interfering gas – nitrogen dioxide
The immune system has evolved to protect the human body against harmful invaders. At the same time, development of tolerance against self-derived and innocuous foreign antigens is of vital importance in order to avoid detrimental immune disorders. In allergic conditions, hypersensitivity is developed against harmless antigens, such as pollen. Dendritic cells (DCs) serve as a link between the innat
The V-BLAST system has been shown to be capable of exploiting the capacity advantage of multiple antenna systems. The square root algorithm for V-BLAST detection is attractive to hardware implementations due to low computational complexity and numerical stability. A low complexity VLSI architecture of the square root algorithm is presented in this paper. The proposed architecture is scalable for v
For studies of Galactic evolution, the accurate characterization of stars in terms of their evolutionary stage and population membership is of fundamental importance. A standard approach relies on extracting this information from stellar evolution models but requires the effective temperature, surface gravity and metallicity of a star obtained by independent means. In previous work, we determined
Streptococcus pneumoniae (pneumococcus) is a major human pathogen, which evolved numerous successful strategies to colonize the host. In this study, we report a novel mechanism of pneumococcal-host interaction, whereby pneumococci use a host complement protein C1q, primarily involved in the host-defense mechanism, for colonization and subsequent dissemination. Using cell-culture infection assays a
Targeted measurements of low abundance proteins in complex mixtures are in high demanded in many areas, not the least in clinical applications measuring biomarkers. We here present the novel platform AFFIRM (AFFInity sRM) that utilizes the power of antibody fragments (scFv) to efficiently enrich for target proteins from a complex background and the exquisite specificity of an SRM-MS based detectio
Copper, zinc superoxide dismutase 1 (SOD1) is a ubiquitous homodimeric enzyme, whose misfolding and aggregation play a potentially key role in the neurodegenerative disease amyotrophic lateral sclerosis (ALS). SOD1 aggregation is thought to be preceded by dimer dissociation and metal loss, but the mechanisms by which the metal-free monomer aggregates remain incompletely understood. Here we use imp
We have previously shown that SRp55 inhibits splicing from HIV-1 exon 3, thereby generating partially spliced mRNAs encoding HIV-1 vpr. Here we show that SRp55 also inhibits splicing from HIV-1 exon 5 to generate HIV-1 vpu/env mRNA, albeit with lower efficiency. We also show that inhibition of HIV-1 splicing by SRp55 causes the appearance of partially spliced vpu, env and vpr mRNAs in the cytoplas
Eosinophils are increasingly recognized as adaptable immune cells that exhibit diverse phenotypes and effector functions across different tissues and disease states. While they can induce pathology through degranulation and cytotoxic mediator release, eosinophils also fulfill regulatory and tissue repair roles. Advances in single-cell and spatial technologies have begun to reveal how microenvironm
BACKGROUND: Although large studies and pooled analyses of individual patient data have demonstrated the safety of deferring coronary revascularization based on a nonischemic intracoronary pressure index result, conflicting findings have emerged in specific patient subsets and with varying follow-up. Thus, we conducted an updated comprehensive systematic review and meta-analysis to investigate the
This chapter explores the links between climate change, environmental degradation, and protracted armed conflicts, focusing on how international law can facilitate effective environmental interventions. It examines how international law, particularly the work of the UN International Law Commission on the Protection of the Environment in relation to Armed Conflicts (PERAC) Principles, international
Brevmall Postadress Kungshuset, 222 22 Lund Besöksadress Kungshuset, Lundagård Telefon dir 046-222 75 93, växel 046-222 00 00 Telefax 046-222 44 24 Internet www.fil.lu.se E-post fil@fil.lu.se Filosofiska institutionen LITTERATURLISTA VT14: HTXF04, VETENSKAPLIG GRUNDKURS, 30 hp Fastställd av Filosofiska institutionens styrelse 2013-08-23 Kurslitteratur för delkurs 1: Vetenskapsteoretisk orientering
https://www.ht.lu.se/media/utbildning/dokument/kurser/HTXF04/20141/Litteraturlista_HTXF04_VT14.pdf - 2026-06-11
