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Small ligaments connecting the fracture surfaces just behind a moving crack front are assumed to exist under certain conditions. The ligaments are rapidly torn as the crack advances. Inelastic straining of such ligaments influences the energy balance in the fracture process. The rapid tearing of a single ligament is studied both numerically and experimentally. An elastic visco-plastic material mod

We report on the observation of the solvation shell rearrangement after abstraction of the electron from aqueous I - in a laser pump/X-ray probe experiment by recording the X-ray absorption L 1 - and L 3 -edge

BACKGROUND: Patients with septic shock may undergo extensive physiological alterations that can alter antibiotic pharmacokinetics. OBJECTIVES: To describe the population pharmacokinetics of ciprofloxacin in septic shock and to define recommendations for effective ciprofloxacin dosing in these patients. METHODS: Adult patients with septic shock treated with ciprofloxacin were eligible for inclusion

The present contribution addresses a crystal plasticity formulation which incorporates hardening effects that are related to the presence of geometrically necessary dislocations. To this end, higher gradient contributions are introduced as additional arguments of the energy function based on microstructural considerations. Extending the derivations presented in Kaiser and Menzel (2019) for a purel

We propose a new structure for the variational auto-encoders (VAEs) prior, with the weakly informative multivariate Student’s t-distribution. In the proposed model all distribution parameters are trained, thereby allowing for a more robust approximation of the underlying data distribution. We used Fashion-MNIST data in two experiments to compare the proposed VAEs with the standard Gaussian priors.

Purpose: After resuscitation from out-of-hospital cardiac arrest (OHCA), renal injury and hemodynamic instability are common. We aimed to assess the association between low cardiac output during targeted temperature management (TTM) and acute kidney injury (AKI) after OHCA. Materials and methods: Single-center substudy of 171 patients included in the prospective, randomized TTM-trial. Hemodynamic

OBJECTIVES: Sedation and neuromuscular blockade protocols in patients undergoing targeted temperature management after cardiac arrest address patient discomfort and manage shivering. These protocols vary widely between centers and may affect outcomes. DESIGN: Consecutive patients admitted to 20 centers after resuscitation from cardiac arrest were prospectively entered into the International Cardia

Goda kamrater, ett antal buteljer punsch, en droska, och en likkista av barnmodell – vad är det värsta som kan hända? I lundastudenten Carl Lindells fall slutade det riktigt illa, med både tidningsskriverier och rektorsförhör. Arkivarien vid universitetsarkivet Henrik Ullstad berättar historien om en Malmöutflykt på 1880-talet som tog en ände med förskräckelse.Good companions, numerous bottles of punsch, a carriage and a child-sized coffin – what could possibly go wrong? In the case of Lund student Carl Lindell, it all went horribly wrong, with stories in the newspapers and being taken before the vice-chancellor. University Library archivist, Henrik Ullstad, tells the story of a Malmö excursion in the 1880s that came to an alarming end.

Investigations mapped the region(s) on the light chain of high molecular weight kininogen (HK) that participates in cell binding. Sequential and overlapping peptides of domain 5 (D5(H)) were synthesized to determine its cell binding site(s). Three peptides from non-overlapping regions on D5(H) were found to inhibit biotin-HK binding to endothelial cells. Peptides GKE19 and HNL21 weakly inhibited b

Background: We recently reported a sensitivity of 85.5% to detect high-grade squamous intraepithelial lesions (HSIL)/adenocarcinoma in situ (AIS)/cancer by the use of self-collected vaginal samples analysed by the Aptima mRNA HPV assay (AHPV). Objectives: To increase detection of HPV among self-samples. Study design: We used a pre-heating step at 90 °C for 1 h on our previously AHPV-negative self-

Allergic skin diseases caused by low molecular weight chemical compounds are a major health concern among the general population, especially in certain occupational groups. To limit exposure to such compounds, it is important that thorough risk assessments are performed before products reach the consumer market. Traditionally, such risk assessments have been based on animal tests, but due to sever

Neutrophil influx to mucosal surfaces represents one of the earliest inflammatory responses to mucosal infection. We have been studying external interactions with urinary tract epithelial cells in an attempt to understand the molecular mechanisms behind this process. Uropathogenic Escherichia coli induced urinary tract epithelial cells to secrete the neutrophil chemoattractant interleukin-8 (IL-8)

Epithelial cell lines produce the cytokines IL-1α, IL-6 and IL-8 when stimulated with Escherichia coli. The cytokine response is enhanced by P fimbriae. The epithelial cell lines also respond to stimulation with other cytokines. These in vitro findings were confirmed in vivo in patients with E. coli infection who secreted IL-6 and IL-8 into the urine. The observations suggest that epithelial cells

Split Vision Urbanism HK is a design research project located at the intersection of urban governance, architectural design, and media arts. It seeks to critically address the relationship between formal and informal structures in order to uncover the hidden potentials of porous urban space, extracting new territories for design practices to engage the generative aspects of high density. Drawing o