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We have previously shown that SRp55 inhibits splicing from HIV-1 exon 3, thereby generating partially spliced mRNAs encoding HIV-1 vpr. Here we show that SRp55 also inhibits splicing from HIV-1 exon 5 to generate HIV-1 vpu/env mRNA, albeit with lower efficiency. We also show that inhibition of HIV-1 splicing by SRp55 causes the appearance of partially spliced vpu, env and vpr mRNAs in the cytoplas
In this chapter, I argue that moving as a way to counter the negative aspects of ageing (actual as well as symbolic), is both dependent on mobility and contradictory to it. The overall purpose is to investigate the relation between moving and mobility in the accounts told by people who have chosen to migrate as seniors in order to enable a certain lifestyle. In what way does the discursive ideal o
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The Thomson multitaper estimator has become successful for spectrum analysis in many application areas. From the aspect of efficient implementation, the so called Welch or WOSA- Weighted Overlap Segment Averaging, has advantages. In the Welch estimator, the same, time-shifted, window is applied to the data-sequence. In this submission, the aim is to find a Welch estimator structure which has a sim
Many computer interfaces and assistive devices for people with motor disabilities limit the input dimensionality from user to system, in many cases leading to single switch interfaces where the user can only press one button. This can, either limit the level of direct access to the functionalities of the operating system, or slow down speed of interaction. In this paper we present TongueWise: a so
The brain is considered to be an immune privileged site, because the blood-brain barrier limits entry of blood borne cells and proteins into the central nervous system (CNS). As a result, the detection and clearance of invading microorganisms and senescent cells as well as surplus neurotransmitters, aged and glycated proteins, in order to maintain a healthy environment for neuronal and glial cells
COPD is a progressive disease, which can take different routes, leading to great heterogeneity. The aim of the post-hoc analysis reported here was to perform continuous analyses of advanced lung function measurements, using linear and nonlinear regressions.
Accurate and internationally comparable human papillomavirus (HPV) DNA genotyping is essential for HPV vaccine research and for HPV surveillance. The HPV Laboratory Network (LabNet) has designed international proficiency studies that can be issued regularly and in a reproducible manner. The 2011 HPV genotyping proficiency panel contained 43 coded samples composed of purified plasmids of 16 HPV typ
Background: Outcome measures can be used to improve the quality of the rehabilitation by identifying and understanding which variables influence the outcome. This information can be used to improve outcomes for clients. In clinical practice, pure-tone audiometry, speech reception thresholds (SRTs), and speech discrimination scores (SDSs) in quiet or in noise are common assessments made prior to he
The following study investigates the female main character in the novel The Bad Girl (2006), written by the Peruvian author Mario Vargas Llosa. In addition, it examines how she relates to the Marianismo, the Latin-American ideology that proposes that the woman's spiritual and moral capacity is superior to the man's, and favours the woman's sexual passivity and purity. The essay is base
Fiji has been plagued with issues hindering its economic development. Having experienced 4 coup d’états in the last 40 years owing to tension between the countries’ two majority ethnic groups, Fiji has developed a reputation for political instability. Lacklustre growth, weak structural transformation, and limited economic diversification have led to increased poverty levels. With the Covid-19 pand
The meaning of human rights locally can vary depending on a city's context. Therefore, the approaches of working with human rights locally can differ. Swedish municipalities tend to lack a structure of approaching human rights. However, the European Union Agency for Fundamental Rights (FRA) is about to publish a framework for how European human rights cities can approach human rights. This t
Human Rights in Malaysia Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human Rights International Humanitari
https://rwi.lu.se/2015/09/29/when-you-do-something-good-you-dont-have-to-get-permission-from-anyone/ - 2026-07-24
Working to increase the sustainability of agriculture is a complex challenge of balancing food production and economic profitability with environmental and climatic impact. As the second largest exporter of agricultural products worldwide, the Netherlands is a global production hub, a leading example of high yields per hectare. However, with this high productivity comes intensive farming practices
Contributing 3% of global annual carbon emissions, the shipping sector has to do its part to keep the global temperature under the maximum increase of 2°C. To fulfil this target, the Netherlands conceived the ‘Green Deal on Maritime and Inland Shipping and Ports’ in 2019. This thesis aims to make a preliminary assessment on the policy’s effectiveness by applying Weber et al.’s environmental pol
Following Kosovo’s issuance of a unilateral declaration of independence in 2008, the UN General Assembly requested the International Court of Justice to pronounce itself on the accordance with international law of the declaration of independence. The Court’s answer to that request was that the declaration of independence was not in violation of international law. When the Court rephrased the quest
Kurslitteratur för CÖSM36, Asienstudier: Social Justice and Equality in Asia, HT 2019 7,5 högskolepoäng Asian Studies: Social Justice and Equality in Asia, 7,5 credits Avancerad nivå / Second Cycle Sidsel Hansson är huvudlärare och har sammanställt litteraturlistan. Kursens syfte är att göra det möjligt för studenterna att ställa frågor och utforma studier om social (o)rättvisa och social (o)jämli
https://www.historiska.lu.se/media/utbildning/dokument/kurser/COSM36/20192/CO_SM36_literature.docx - 2026-07-24
There is an ever-growing interest among researchers and practitioners in base of the pyramid (BOP) markets. Still, the distinguishable challenges in terms of presenting a viable business model at the BOP are evident both in research and practice. This thesis aims to examine how private sector firms can innovate business models to attend to the BOP. A qualitative research approach in the form of a
BACKGROUND: Although large studies and pooled analyses of individual patient data have demonstrated the safety of deferring coronary revascularization based on a nonischemic intracoronary pressure index result, conflicting findings have emerged in specific patient subsets and with varying follow-up. Thus, we conducted an updated comprehensive systematic review and meta-analysis to investigate the
This chapter explores the links between climate change, environmental degradation, and protracted armed conflicts, focusing on how international law can facilitate effective environmental interventions. It examines how international law, particularly the work of the UN International Law Commission on the Protection of the Environment in relation to Armed Conflicts (PERAC) Principles, international
