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We propose a new algorithm for feedback nonlinear synthesis. The algorithm computes suboptimal solutions, with bounds on suboptimality, to the Hamilton-Jacobi-Bellman equation. For systems that are modeled with polynomials the computations can be done efficiently via semidefinite programming. To illustrate the strength of the proposed method, we computesmooth stabilizing feedback controllers for s
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Popular Abstract in Swedish Avhandlingen ”Vänskap och organisering. En studie av Fountain House-rörelsen” tar sin utgångspunkt i frågan om vad som händer när mentalsjukhusen läggs ner. Bakgrunden är den process som kallas avinstitutionaliseringen, och tidens betoning på integrering, normalisering och självbestämmande. Omstruktureringen av mentalvården har inte varit problemfri i något land. Många The Fountain House Movement – or the Clubhouse Movement - is an organization for community support, meeting the needs of adults suffering from mental illness. It was founded by a self-help group among discharged patients in New York in the 1940s. Today there are more than 300 clubhouses around the world. The aim of this dissertation is to characterize, interpret and understand the Clubhouse Moveme
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The stability toward thermal and urea denaturation was measured for HAMLET (human -lactalbumin made lethal to tumor cells) and -lactalbumin, using circular dichroism and fluorescence spectroscopy as well as differential scanning calorimetry. Under all conditions examined, HAMLET appears to have the same or lower stability than -lactalbumin. The largest difference is seen for thermal denaturation o
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Escherichia coli stimulates neutrophil migration across human uroepithelial cell layers. This study investigated the role of the neutrophil chemokine interleukin-8 (IL-8) in this process. E. coli and IL-1alpha stimulated urinary tract epithelial layers to secrete IL-8 and induced transepithelial neutrophil migration. Anti-IL-8 antibody reduced neutrophil migration across epithelial cell layers, in
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OBJECTIVES: To evaluate the health-related quality of life (HRQL) of patients with head and neck cancer during and after treatment with radiotherapy, surgery, and chemotherapy. STUDY DESIGN: Prospective, descriptive study. METHODS: All new patients in four institutions in Norway and Sweden were asked to participate. Health-related quality of life was assessed at baseline and at 1, 2, 3, 6, and 12
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“Die Unruhe und Ungewissheit sind unser Theil”, writes Goethe in a letter to the German novelist Sophie von la Roche in 1774. But is it the incalculable and indeterminate that cause disquiet, or is it our bustling pursuit of knowledge that makes us uncertain? Contemporary psychologists have taught us a great deal about the way we perceive risks and about the way affects and emotions influence our
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Infection with Trichomonas vaginalis may be asymptomatic or with symptoms suggestive of vaginitis. Because cysteine proteinase 30 (CP30) of T. vaginalis is known to be a virulence marker that plays a role in cytoadherence, the aim of this study was to analyse the presence of CP30 and antibody to CP30 in clinical samples of symptomatic and asymptomatic infected women. CP30 was detected in all the s
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Surface-associated plasmin(ogen) may contribute to the invasive properties of various cells. Analysis of plasmin(ogen)-binding surface proteins is therefore of interest. The N-terminal variable regions of M-like (ML) proteins from five different group A streptococcal serotypes (33, 41, 52, 53 and 56) exhibiting the plasminogen-binding phenotype were cloned and expressed in Escherichia coli. The re
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Cellulär kommunikation utvecklas ständigt; för närvarande installeras 5G-system och forskning kring 6G pågår. Tre användningsfall som diskuteras är enhanced mobile broadband (eMBB), massive machine-type communication (mMTC) och ultra-reliable low-latency communication (URLLC). För att uppfylla kraven i dessa användningsfall behövs ny teknik och en kandidat är massive multiple-input multiple-outputCellular communication is constantly evolving; currently 5G systems are being deployed and research towards 6G is ongoing. Three use cases have been discussed as enhanced mobile broadband (eMBB), massive machine-type communication (mMTC), and ultra-reliable low-latency communication (URLLC). To fulfill the requirements of these use cases, new technologies are needed and one enabler is massive mult
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Popular Abstract in Swedish SVENSK SAMMANFATTNING Huvudsyftet med denna avhandling var att undersöka olika aspekter av självrapporterade sexuella övergrepp under barndom och ungdomstid i en befolkningsstudie med svenska gymnasieelever. Ett av målen var att undersöka livstidsprevalensen för olika typer av sexuella övergrepp och olika övergreppsvariabler samt relationen mellan sexuella övergrepp, köABSTRACT The purpose of this thesis was to investigate aspects of self-reported sexual abuse during childhood and adolescence in a population-based study of Swedish high school students. The aim of this thesis was first to investigate the lifetime prevalence of sexual abuse of varying severity and characteristics as well as the associations between sexual abuse, gender, socio-demographic character
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Popular Abstract in Swedish Joniserande strålning används ofta som behandling vid olika tumörsjukdomar i bukhåla och bäckenregion men är ibland förenad med biverkningar. Dessa kan uppkomma tidigt/akut, dvs i direkt anslutning till genomförd behandling eller sent, efter månaderår. Besvären kan vara av mycket varierande och ofta lindrig övergående karaktär såsom buksmärtor, diarré och blödningar fråGastrointestinal tract damage is an insidious feature in patients undergoing radiotherapy. Microvascular inflammation, including leukocyte and platelet recruitment as well as epithelial barrier dysfunction, are considered to constitute key components in the pathophysiology of radiation-induced enteropathy. The aim of this thesis was to investigate the basic mechanisms behind leukocyte-platelet-end
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Popular Abstract in Swedish Cancer är ett samlingsnamn för en grupp av sjukdomar som karakteriseras av att cellerna delar sig okontrollerat, till skillnad mot kroppens friska celler. Det leder till att en tumör kan bildas och cellerna kan därifrån sprida sig till andra delar av kroppen och ge upphov till dottertumörer, även kallade metastaser. I Sverige uppskattar man att cirka var tredje person kSmall cell lung carcinoma (SCLC) is a very aggressive solid tumor and is often widely metastasized by the time of diagnosis. Despite good response to the initial chemotherapy, SCLC cells often develop multidrug resistance to conventionally used chemotherapeutic drugs, which cause almost all SCLC tumors to relapse. The 5-year survival rate for patients with limited disease is around 20% while it is
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Popular Abstract in Swedish Avhandlingen består av tre essäer som behandlar effekterna av inkomplett information i de finansiella marknaderna. Av dessa essäer är två teoretiska och en är huvudsakligen empirisk. Samtliga essäer undersöker effekterna av parameterosäkerhet, och de använder sig av kontinuerliga modeller. Den första essän, "The Effect of Information Quality on Optimal Portfolio ChoiceThis thesis consists of three essays on incomplete information in financial markets, two of which are theoretical, and one that is mainly of an empirical nature. All three essays concern parameter uncertainty, and they employ a continuous-time framework. The first essay, "The Effect of Information Quality on Optimal Portfolio Choice," analyzes the portfolio choices made by three types of agents,
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Popular Abstract in Swedish Avhandlingen består av tre delar. Den första, Från utbildningsmarknad till of-fentlig utbildning. Svensk flickskola 1874-1962, behandlar dels integrationen av flickornas sekundärutbildning i den offentliga utbildningsorganisationen, dels förstärkningen respektive försvagningen av denna speciellt genuskodade utbild-ning. Sekundärutbildningen har varit könssegregerad och The thesis is divided into three sections. The first, “From an education market to public education. The Swedish girls’ school 1874-1962”, deals with the integration of girls’ secondary education into the public education system, as well as with the strengthening and weakening of this special, gender-coded education. Secondary education was gender segregated and integration involved a process of s
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The United States is having an identity crisis concerning it's borders. The terrorist attacks on September 11th, 2001, raised concerns about the nations borders. Year 2002, The Department of Homeland Security was created with the purpose to secure the nation from potential threats related to the borders. This study examine which different American identities have been constructed during the 2
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Failures of environmental law to preserve, protect and improve the environment are caused by law’s contingency and constitutional presumptions of supremacy over the self-regulatory agency of nature. Contingency problems are intrinsic to law and, therefore, invite deployment of technologies. Constitutional presumptions can be corrected through geo-constitutional reform. The latter requires the elab
