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The catalytic cycle of multicopper oxidases (MCOs) involves intramolecular electron transfer (IET) from the Cu-T1 copper ion, which is the primary site of the one-electron oxidations of the substrate, to the trinuclear copper cluster (TNC), which is the site of the four-electron reduction of dioxygen to water. In this study we report a detailed characterization of the kinetic and electrochemical p

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NADH:quinone oxidoreductase or complex I is a large membrane bound enzyme complex that has evolved from the combination of smaller functional building blocks. Intermediate size enzyme complexes exist in nature that comprise some, but not all of the protein subunits in full size 14-subunit complex I. The membrane spanning complex I subunits NuoL, NuoM and NuoN are homologous to each other and to tw

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Background Non-heart-beating donor lung has been a promising source of lung transplantation. Many studies on non-heart-beating donor lungs are based on animal lung transplantation. In this study, we assessed by organ bath the effect of one-hour warm ischemia on the non-heart-beating donor lung in terms of the integrity of contractile and relaxant functions and tissue structures of pulmonic arterie

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The shear-induced transformations between oriented planar lamellae and a state of closely packed multilamellar vesicles (MLVs) in a lyotropic nonionic surfactant model system were studied by the combination of nuclear magnetic resonance (NMR) spectroscopy and diffusometry with magnetic resonance imaging (MRI). H-2 NMR imaging confirmed the discontinuous nature of the transition from onions to plan

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The random phase approximation (RPA) monopole strength and the unperturbed particle-hole excitation strength are studied, in which the strength in the continuum is properly treated without discretizing unbound particle spectra. The model is the self-consistent Hartree-Fock calculation and the RPA Green's function method with Skyrme interactions. Numerical examples are the Ni isotopes, especially N

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Popular Abstract in Swedish Reklamen är ett oundvikligt inslag i vår vardagsmiljö och en viktig del av vår dagliga massmediekonsumtion. I den här studien har jag använt mig av tre italienskspråkiga reklambudskap för olivolja (Carapelli), pasta (Voiello) och kaffe (Lavazza) . I syfte att kunna belysa vilken viktig roll mottagarens sociokulturella bakgrund och encyklopediska kunskapsnivå spelar för The aim of this study is to describe how Italian advertising for olive oil, pasta and coffee reflects traditions, customs and culturally specific patterns regarding the ways in which these products are used in Italy, and how these culturally specific patterns are interpreted by native readers and non-native readers (Swedish students). The study is based on 22 Italian and 22 Swedish interpretations

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We report on our findings of the bright, pulsating, helium atmospherewhite dwarf GD 358, based on time-resolved optical spectrophotometry. Weidentify 5 real pulsation modes and at least 6 combination modes atfrequencies consistent with those found in previous observations. Themeasured Doppler shifts from our spectra show variations with amplitudesof up to 5.5 km s-1 at the frequencies i

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Structural equation modeling on questionnaire data showed that different kinds of prejudice (concerning sexual orientation, ethnicity, gender, and impaired develop­ment) can be represented as a general prejudice factor. Specific variability related to classical and modern prejudice only increased model fit marginally. Several causal models of the relation between key individual difference variable

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Aim To identify clinical, immunological and biochemical factors that predict remission, and its duration in a large cohort of young adults with Type 1 diabetes mellitus (DM). Methods In Sweden 362 patients (15-34 years) classified as Type 1 DM were,, included in a prospective, nation-wide population-based study. All patients were followed at local hospitals for examination of HbA(1c) and insulin d

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This report is based on 1.851 adult patients with soft tissue sarcoma (STS) of the extremities or trunk wall diagnosed between 1986 and 1997 and reported from all tertiary referral centers in Norway and Sweden. The median age at diagnosis was 65 years and the male-to-female ratio was 1.1:1. One third of the tumors were subcutaneous, one third deep, intramuscular and one third deep, extramuscular.

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This study describes the integrated sympathetic/metabolic control of capillary pressure (Pc) and filtration in cat skeletal muscle as studied during graded exercise and superimposed graded (2, 6 and 16 Hz) vasoconstrictor nerve excitation. The applied technique permitted simultaneous analysis of the underlying changes of resistance in the whole vascular bed (RT) and in its large-bore arterial resi

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High-resolution records of plant macrofossils, magnetic susceptibility, and total carbon content, complemented by pollen data, were obtained from a postglacial lake sediment sequence at alpine Lake Stentjarn (987 m a.s.l.), in west-central Sweden. Holocene vegetational and environmental changes were reconstructed from the data, with particular emphasis on the deglacial establishment of terrestrial

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The adsorption of whey proteins on modified and unmodified 316 2R stainless steel surfaces was studied by in situ ellipsometry under well-defined flow conditions. The effects of bulk properties, e.g. temperature, pH, protein concentration and flow rate as well as surface modification by ion implantation, sputtering, chemical vapour deposition and silica sol-gel deposition, were investigated. The s

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Human cystatin C (HCC) shows a tendency to dimerize. This process is particularly easy in the case of the L68Q HCC mutant and might lead to formation of amyloid deposits in brain arteries of young adults. Our purpose was to find ligands of monomeric HCC that can prevent its dimerization. Eleven antisense peptide ligands of monomeric HCC were designed and synthesized. The influence of these ligands

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Popular Abstract in Swedish Hjärnan består av hjärnbarken, även kallad den grå substansen, och den underliggande vita substansen. Den grå substansen med alla nervceller svarar bland annat för våra kognitiva funktioner som gör var och en av oss till unika individer. Medvetande, minne, språk och tal liksom ilska och glädje är alla exempel på egenskaper och funktioner som styrs från den grå substanseAlzheimer's disease (AD) is the most prevalent type of dementing disorder. The cortical pathology of AD has been recognized for almost a century. In later years, an associated pathological feature of AD has been identified which affects the white matter. This white matter disease (WMD), defined in the microscope, consists of a subtotal tissue loss of the white matter structural components. WMD is

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To model the structural and functional parts of the water oxidizing complex in Photosystem II, a dimeric manganese(II,II) complex (1) was linked to a ruthenium(II)tris-bipyridine (Ru(II)(bpy)(3)) complex via a substituted L-tyrosine, to form the trinuclear complex 2 [J. Inorg. Biochem. 78 (2000) 15]. Flash photolysis of 1 and Ru(II)(bpy)(3) in aqueous solution, in the presence of an electron accep

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Fifteen years after the heavy storm "Vivian", it is still not clear how succession in subalpine forests that were affected by the storm will continue and when regrowing forests will provide effective protection from natural hazards such as avalanches. We used a simulation model to evaluate forest succession, forest structure and the protective effect in subalpine blowdown areas after 50 simulation

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Objective To standardize the evaluation of regional fetal brain blood perfusion, using power Doppler ultrasound (PDU) to estimate the fractional moving blood volume (FMBV) and to evaluate the reproducibility of this estimation. Methods Brain blood perfusion was evaluated in 35 normally grown fetuses at 28-30 weeks of gestation, using PDU. The following cerebral regions were included in the PDU col