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The etiology of human leukocyte antigen (HLA)-associated organ-specific autoimmune diseases is incomplete. In type 1 diabetes and celiac disease, the strongest associations are with the HLA-DR3-DQ2 and DR4-DQ8 haplotypes, whereas the DQB1*06:02 allele has a strong negative association. In contrast, narcolepsy, especially as recently triggered by the Pandemrix® H1N1 vaccine (GlaxoKlineSmith (GSK),

The myc family of genes contains five functional members. We describe the cloning of a new member of the myc family from rat genomic and cDNA libraries, designated B-myc. A fragment of cloned B-myc was used to map the corresponding rat locus by Southern blotting of DNA prepared from rat X mouse somatic cell hybrids. B-myc mapped to rat chromosome 3. We have previously mapped the c-myc to rat chrom

Using Swedish firm-level data on all firms and their affiliates abroad, we investigate what observable firm and country characteristics affect the size of affiliate firms in a particular destination. We employ the richness of the data to investigate the importance of destination country factors in explaining firm outward FDI activities and distinguish between the factors that affect such activitie

A separation between the academic subjects statistics and mathematical statistics has existed in Sweden almost as long as there have been statistics professors. The same distinction has not been maintained in other countries. Why is it kept in Sweden?In May 2015 it has been 100 years since Mathematical Statistics was formally established as an academic discipline at a Swedish university where Stat

There is a clear trend in rich countries that despite rising incomes and living standards, the gap between rich and poor is widening. What does this mean for our health? Does increasing income inequality affect outcomes such as obesity, life expectancy and subjective well-being? Are rich and poor groups affected in the same ways? This book reviews the latest research on the relationship between in

We calculated the cross section for the exclusive double-diffractive bb̄ production in pp→p(bb̄)p reaction at LHC. Large cross sections are obtained (3-10nb). This process constitutes the irreducible background to the exclusive Higgs production and is of particular importance in the upcoming Higgs boson searches. The distribution in invariant mass of the bb̄ pair is calculated and compared with th

In this article we report on how 64 dentists working in a big city in southern Sweden view their profession. The dentists ranged in age from 30 to 70 years (as it was indicated in intervals of 10 years). Their professional experience ranged from 2 to 44 years (mean, 23 years). We collected their views on the ideal skills of a good dentist by means of a questionnaire. From this material we identifi

This paper presents an approach to the synthesis of low-power fault-tolerant hard real-time applications mapped on distributed heterogeneous embedded systems. Our synthesis approach decides the mapping of tasks to processing elements, as well as the voltage and frequency levels for executing each task, such that transient faults are tolerated, the timing constraints of the application are satisfie

Custom architectures are often adopted as more efficient alternatives to general purpose processors in terms of performance and power. However, the design of such architectures requires experts both in hardware and the application domain. In this paper we propose a method for speeding up the design space exploration. Our method, based on Pareto points, identifies sets of solutions in terms of scal

BACKGROUND: Obesity is more common in people with mobility disability than in non-disabled individuals, but less is known about the longitudinal effects leading to this health state.OBJECTIVE: To explore the potential bidirectional association between mobility disability and obesity.METHODS: Participants were identified in the population-based Stockholm Public Health Cohort (2002-2010, n = 17 945)

Using ultralow-power wake-up receivers (WRxs) can reduce idle listening energy cost in wireless sensor networks with low traffic intensity. This has led to many WRx analog front-end (AFE) designs presented in literature, with a large variety of trade-offs between the sensitivity, the data rate, and the power consumption. Energy consumed during wake-up in a network depends on many parameters and wi

Background: There are knowledge gaps about the life situation for people ageing with Parkinson's disease (PD), with virtually no understanding of home and health dynamics. Therefore, the aim of the present study was to explore the association between aspects of health and objective as well as perceived housing in people with PD. Methods: Participants were recruited from three hospitals in the regi

This contribution presents a novel model-based methodology for open-loop optimal control of batch high-pressure liquid chromatographic (HPLC) separation processes. The framework allows for simultaneous optimization of target component recovery yield and production rate with respect to a parameterization of the input elution trajectory and fractionating interval endpoints. The proposed methodology

OBJECTIVE: To examine whether a shift in work-related bullying status, from being non-bullied to being bullied or vice versa, was associated with changes in reporting of personality characteristics.METHODS: Data on bullying and personality (neuroticism, extraversion, and sense of coherence) were collected in three waves approximately 2 years apart (N = 4947). Using a within-subjects design, person