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The tropical Pacific Ocean plays a significant role in climate change, and the El Niño-Southern Oscillation (ENSO) is considered to be closely related to extreme climate phenomenon worldwide. However, the evolution of the ENSO-like patterns in the tropical Pacific during the Pleistocene glacial cycles remains controversial. In this study, we present geochemical indices and a transient model simula
Business angels are a vital source of capital for innovative start-up firms. However, many potentially attractive investment opportunities are rejected during the angel's decision-making process. Information asymmetry, risk and distrust in the relationship between the investor and the entrepreneur result in investment barriers. The concept of proximity has been proposed as a conceptual foundation
Habitat loss and population fragmentation pose severe threats to biodiversity and the survival of many species. Population isolation and the decline in effective population size lead to increased genetic drift and inbreeding. In turn, this reduces neutral diversity, and it also affects the genetic load of deleterious mutations. Here, we analyse the effect of such genomic erosion by designing a spa
Social inclusion and the importance of work in developing countries has been an increasing topic of conversation during recent AIS conferences, and there are calls for research into ‘making a better world with ICT’. Trauth (2017) in her ‘Research Agenda for Social Inclusion in Information Systems’ states that “social inclusion in the information systems field is a research topic whose time has com
Small angle X-ray scattering has been proven to be a valuable method for accessing structural information below the spatial resolution limit implied by direct imaging. Here, we theoretically derive the relation that links the subpixel differential phase signal provided by the sample to the moments of scattering distributions accessible by refraction sensitive X-ray imaging techniques. As an import
ABC-stacked multilayer graphene (ABC-MLG) exhibits topological surface flat bands with a divergent density of states, leading to many-body instabilities at charge neutrality. Here, we explore electronic ordering within a mean-field approach with full generic treatment of all spin-isotropic, two-site charge density and spin interactions up to next-nearest-neighbor (NNN) sites. We find that surface
Context. Gaia Data Release 3 (Gaia DR3) contains the second release of the combined radial velocities. It is based on the spectra collected during the first 34 months of the nominal mission. The longer time baseline and the improvements of the pipeline made it possible to push the processing limit from GRVS= 12 in Gaia DR2 to GRVS= 14 mag. Aims. We describe the new functionalities implemented for
In recent years, the need for affordable sustainable housing has increased. At the same time, there has been a gradual rising interest in compact living. With the mounting impacts of climate change, a new way of thinking is needed to develop more resilient and climate responsive ways of living that are compact, affordable, and climate-conscious. In response to this need, the idea of a ‘Z-Free Home
A search for resonances in events with at least one isolated lepton (e or μ) and two jets is performed using 139 fb −1 of s = 13 TeV proton–proton collision data recorded by the ATLAS detector at the LHC. Deviations from a smoothly falling background hypothesis are tested in three- and four-body invariant mass distributions constructed from leptons and jets, including jets identified as originatin
The Gaia-ESO Survey is a public spectroscopic survey that targeted ≲105 stars covering all major components of the Milky Way from the end of 2011 to 2018, delivering its final public release in May 2022. Unlike other spectroscopic surveys, Gaia-ESO is the only survey that observed stars across all spectral types with dedicated, specialised analyses: from O (Teff ∼ 30 000-52 000 K) all the way to K
Cows produce saliva in very large quantities to lubricate and facilitate food processing. Estimates indicate an amount of 50–150 L per day. Human saliva has previously been found to contain numerous antibacterial components, such as lysozyme, histatins, members of the S-100 family and lactoferrin, to limit pathogen colonization. Cows depend on a complex microbial community in their digestive syste
Locust bean gum (LBG) is an industrially important polysaccharide used widely in food, cosmetics, textiles, and biopharmaceutical applications, where understanding its solution behaviour is important for formulation design. To address this, we investigate the structure and dynamics of LBG in aqueous solution using steady state shear rheology, static light scattering (SLS), ultra-small-angle light
Antagonistic coevolution (i.e., reciprocal adaptation and counter-adaptation) between hosts and pathogens has long been considered an important driver of genetic variation. However, direct evidence for this is still scarce, especially in vertebrates. The wealth of data on genetics of susceptibility to infectious disease in humans provides an important resource for understanding host-pathogen coevo
The production, transport, and deposition of mineral dust exert major influences on climate change and Earth’s biogeochemical cycles. Furthermore, their imprint, as recorded in pelagic sediments, provides an avenue for determining past changes in terrestrial aridity and atmospheric circulation patterns in response to global climate change. Here, by examining geochemical and magnetic data obtained
Scene and object information reach the entorhinal-hippocampal circuitry in partly segregated cortical processing streams. Converging evidence suggests that such information-specific streams organize the cortical – entorhinal interaction and the circuitry’s inner communication along the transversal axis of hippocampal subiculum and CA1. Here, we leveraged ultra-high field functional imaging and adv
The pharmacologic and pharmacokinetic properties were evaluated in a series of antiuterotonic oxytocin analogs, modified at positions 1, 2, 4, 8 and, in one case, position 9 of the oxytocin (OT) molecule. [Mpa1,D-Tyr2(Et),Val4,Orn8,desGly9]-OT, [Mpa1,Tyr2(Et),Val4,Orn8]-OT and [Mpa1,D-Tyr2,Val4,Orn8]-OT displayed similar plasma clearance rates (Clps) using the constant infusion method in rats. Two
This article argues that Islamic authorities do not try to sustain a jurisdiction over Islamic divorce in Denmark. They respond to a juridical demand caused by the absence of Islamic legal institutions in Denmark, which I call the Islamic juridical vacuum. This vacuum entails that sharia is often defined locally in communities or families rather than by Islamic authorities, and when women are unab
BACKGROUND. α1-antichymotrypsin (ACT) forms stable complexes with prostate-specific antigen (PSA), a serine protease, and this complex is the major form of PSA in the blood circulation. α1-antichymotrypsin occurs in the blood in approximately 105 molar excess to PSA, mainly due to hepatic production, but local prostatic production of ACT has been demonstrated by immunohistochemistry and in situ hy
