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Hematologically important mutations : The autosomal forms of chronic granulomatous disease (third update)

Chronic granulomatous disease (CGD) is an immunodeficiency disorder affecting about 1 in 250,000 individuals. CGD patients suffer from severe, recurrent bacterial and fungal infections. The disease is caused by mutations in the genes encoding the components of the leukocyte NADPH oxidase. This enzyme produces superoxide, which is subsequently metabolized to hydrogen peroxide and other reactive oxy

Ibrutinib combined with immunochemotherapy with or without autologous stem-cell transplantation versus immunochemotherapy and autologous stem-cell transplantation in previously untreated patients with mantle cell lymphoma (TRIANGLE) : a three-arm, randomised, open-label, phase 3 superiority trial of the European Mantle Cell Lymphoma Network

Background: Adding ibrutinib to standard immunochemotherapy might improve outcomes and challenge autologous stem-cell transplantation (ASCT) in younger (aged 65 years or younger) mantle cell lymphoma patients. This trial aimed to investigate whether the addition of ibrutinib results in a superior clinical outcome compared with the pre-trial immunochemotherapy standard with ASCT or an ibrutinib-con

A blood test to monitor bee health across a European network of agricultural sites of different land-use by MALDI BeeTyping mass spectrometry

There are substantial concerns about impaired honey bee health and colony losses due to several poorly understood factors. We used MALDI profiling (MALDI BeeTyping®) analysis to investigate how some environmental and management factors under field conditions across Europe affected the honey bee haemolymph peptidome (all peptides in the circulatory fluid), as a profile of molecular markers represen

Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway

TP53 is the most frequently mutated gene in human cancer. This gene shows not only loss-of-function mutations but also recurrent missense mutations with gain-of-function activity. We have studied the primary bone malignancy osteosarcoma, which harbours one of the most rearranged genomes of all cancers. This is odd since it primarily affects children and adolescents who have not lived the long life

ASPCAP : The APOGEE STELLAR PARAMETER and CHEMICAL ABUNDANCES PIPELINE

The Apache Point Observatory Galactic Evolution Experiment (APOGEE) has built the largest moderately high-resolution (R ≈ 22,500) spectroscopic map of the stars across the Milky Way, and including dust-obscured areas. The APOGEE Stellar Parameter and Chemical Abundances Pipeline (ASPCAP) is the software developed for the automated analysis of these spectra. ASPCAP determines atmospheric parameters

TOI-544 b:ã potential water-world inside the radius valley inã two-planet system

We report on the precise radial velocity follow-up of TOI-544 (HD 290498),ã bright K star ( V = 10.8), which hostsã small transiting planet recently disco v ered by the Trãnsiting Exoplanet Survey Satellite (TESS) . We collected 122 high-resolution High Accuracy Radial velocity Planet Searcher (HARPS)ãnd HARPS-N spectra to spectroscopically confirm the transiting planetãnd measure its mass. The ne

SPIRIT-Children and Adolescents (SPIRIT-C) 2026 extension statement : enhancing the reporting and usefulness of paediatric randomised trial protocols

Randomised controlled trial (RCT) protocols contain essential details needed to understand and evaluate the trial's planned aims, design, data collection methods, monitoring, data analysis, and participants' safety. However, key information is often omitted from paediatric RCT protocols, including details on dose adjustments of interventions based on age, body surface area, or weight; developmenta

SPIRIT-Children and Adolescents (SPIRIT-C) 2026 extension statement: enhancing the reporting and usefulness of paediatric randomised trial protocols

Randomised controlled trial (RCT) protocols contain essential details needed to understand and evaluate the trial's planned aims, design, data collection methods, monitoring, data analysis, and participants' safety. However, key information is often omitted from paediatric RCT protocols, including details on dose adjustments of interventions based on age, body surface area, or weight; developmenta

An accurate fully automated panel of plasma biomarkers for Alzheimer's disease

Introduction: There is a great need for fully automated plasma assays that can measure amyloid beta (Aβ) pathology and predict future Alzheimer's disease (AD) dementia. Methods: Two cohorts (n = 920) were examined: Panel A+ (n = 32 cognitively unimpaired [CU], n = 106 mild cognitive impairment [MCI], and n = 89 AD) and BioFINDER-1 (n = 461 CU, n = 232 MCI). Plasma Aβ42/Aβ40, phosphorylated tau (p-

Modern quantum chemistry with [Open]Molcas

MOLCAS/OpenMolcas is an ab initio electronic structure program providing a large set of computational methods from Hartree-Fock and density functional theory to various implementations of multiconfigurational theory. This article provides a comprehensive overview of the main features of the code, specifically reviewing the use of the code in previously reported chemical applications as well as mor

Ha-Torah - den största gåvan eller den tyngsta bördan? Judisk och kristen tolkningstradition

The Jewish concept of Torah (Ha-Torah) is often described as “the Greatest Gift,” especially among Jews themselves. Within the Christian tradition, especially the Lutheran, the Torah seems to reflect rather the opposite – a heavy burden. This essay addresses the relevant issues concerning the Concept of Torah. What does it mean? What is the Torah of significance for Judaism and Christianity in the

Yogafobi : en diskurskritisk analys av tidningarna Dagen och Världen idag av dess kritik mot yoga i Sverige utifrån historiebruk

This Master’s thesis is a study of the existence of yogaphobia in the swedish debate between the years 2012 and 2020 concerning the religious nature yoga. Via deconstructing misconceptions of yoga from a historical standpoint combined with the use of critical discourse analysis, the thesis explores the arguments found in news articles and submitters from the swedish newspapers Dagen and Världen id

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Division of Solid Mechanics ISRN LUTFD2/TFHF11/5161SE (1-94) SIMULATION AND TESTING OF GPHE CHANNEL PLATES DURING ASSEMBLING Master's Dissertation by Henrik Forsbäck and Joel Johansson Supervisors Ph. D. Håkan Hallberg, Div. of Solid Mechanics, Lund M. Sc. Joakim Krantz, Alfa Laval Lund AB M. Sc. Anders Lüning, Alfa Laval Lund AB Examiner Ph. D. Mathias Wallin, Div. of Solid Mechanics, Lund Copyri

https://www.solid.lth.se/fileadmin/hallfasthetslara/utbildning/examensarbete/TFHF5161.pdf - 2026-05-18

Master’s Dissertation Structural Mechanics Report TV SM -5237 O M A R C H O U M A N STA TIC A N D D Y N A M IC CH A RA CTERIZA TIO N O F ELA STO M ER S B Y A M O D IFIED H A R D N ESS TEST OMAR CHOUMAN STATIC AND DYNAMIC CHARACTERIZATION OF ELASTOMERS BY A MODIFIED HARDNESS TEST DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--19/5237--SE (1-71) | ISSN

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5237.pdf - 2026-05-18

Microsoft Word - M Almqvist, B Larsson.doc

Microsoft Word - M Almqvist, B Larsson.doc Abstract — Ansökningstalen för Elektroteknikprogrammet, LTH, har sedan IT-kraschen 2000 minskat kraftigt. Detta fenomen är inte unikt för Lund utan kan noteras på Sveriges övriga tekniska högskolor och internationellt i västvärlden. De programansvariga har under flera år varit medvetna om problemen och har på bred front försökt att möta de nya förutsättni

https://www.lth.se/fileadmin/lth/genombrottet/konferens2008/M_Almqvist__B_Larsson.pdf - 2026-05-19

Standard-mall för AMS

Standard-mall för AMS Sida: 1 av 12 2011-03-24 Diarienr: Af-2011/093179 Avtal mellan Arbetsförmedlingen och Saco-S Arbetsförmedlingen avseende löneförhandlingar enligt Ramavtal om löner m.m. (RALS 2010-T) Avtalstidens längd 1 § Parterna träffar ett tillsvidareavtal om löner m.m. Avtalet gäller från och med den 1 oktober 2010. Inriktning för lönerevision 2 § Parterna på myndighetsnivå ska inför var

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/arbetsformedlingen-af/dokument/avtalafochsacorals2010.pdf - 2026-05-19