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Ca(2+)-ATPases are ATP-driven membrane pumps that are responsible for the transport of Ca(2+) ions across the membrane. The Listeria monocytogenes Ca(2+)-ATPase LMCA1 has been crystallized in the Ca(2+)-free state stabilized by AlF(4)(-), representing an occluded E2-P(i)-like state. The crystals belonged to space group P2(1)2(1)2 and a complete data set extending to 4.3 Å resolution was collected.

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Everyday international political economy (EIPE) offers an opportunity to rethink the role of individuals and citizenry in shaping governance of natural resources. In South Africa, significant progress has been made by government in re-shaping water governance since the end of apartheid in the early 1990s. The role of government in water governance and water politics has thus been emphasised to a l

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The article investigates whether the history of individuals’ spatial relocation has an impact on their propensity to perform an entrepreneurial entry and post-entry performance of firms they start. By looking at entrepreneurs in the IT services sector in Swedish non-core regions between 1991 and 2010, the article investigates the interaction between individuals’ embeddedness in local networks and

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Aim: To determine statistical relationships between the prevalence of haemosporidian (malaria) parasites and the abundance of avian host populations across islands in the Lesser Antilles. Location: Thirteen islands in the Lesser Antilles, from Grenada in the south to St Kitts in the north. Methods: Birds were captured by mist net and small blood samples were taken for polymerase chain reaction and

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The Paleoproterozoic Era witnessed crucial steps in the evolution of Earth's surface environments following the first appreciable rise of free atmospheric oxygen concentrations ∼2.3 to 2.1 Ga ago, and concomitant shallow ocean oxygenation. While most sedimentary successions deposited during this time interval have experienced thermal overprinting from burial diagenesis and metamorphism, the ca. 2.

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Overbank flooding caused by historically high flows, such as that in the Rio Mundaú watershed (lying between the states of Alagoas and Pernambuco) in 2010, has been the cause of widespread damage. The purpose of work described in this paper was to propose a mapping of areas liable to flooding in the township of Rio Largo (Alagoas) in the Rio Mundaú watershed by means of an “off-line” coupling of t

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Using a unique survey data set this paper documents a positive effect of self-employment in farming on subjective well-being. This direct effect is only partly offset by negative, indirect effects working through income and other variables. These findings are interpreted as effects of self-employment in farming on perceived autonomy, competence and relatedness. The results suggest that economic tr

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Aims: The quality registry SWEDEHEART covers data across the patient pathway after an acute myocardial infarction (MI), from hospital care to secondary prevention. Although cardiac rehabilitation (CR) is strongly recommended after an MI, there is still heterogeneity regarding standards, uptake, and adherence rates. The aim of the SWEDEHEART-CR registry is to provide continuous information on secon

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In this article an analytical equation for calculating the theoretical arithmetic mean surface roughness, Ra, in the case of turning using a tool with a circular nose radius is presented. The deviation that often occurs between the expected and the obtained surface roughness during these machining operations is investigated. Influence of the minimum chip thickness is discussed especially in regard

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Tree-killing bark beetles are the most economically important insects in conifer forests worldwide. However, despite >200 years of research, the drivers of population eruptions and crashes are still not fully understood and the existing knowledge is thus insufficient to face the challenges posed by the Anthropocene. We critically analyze potential biotic and abiotic drivers of population dynamics

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Purpose: Previous studies using FLASH radiotherapy (RT) in mice showed a marked increase of the differential effect between normal tissue and tumors. To stimulate clinical transfer, we evaluated whether this effect could also occur in higher mammals. Experimental Design: Pig skin was used to investigate a potential difference in toxicity between irradiation delivered at an ultrahigh dose rate call

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A large number of experiments in successive tests of episodic memory have focused on an experimental paradigm called recognition failure of recallable words. In this paradigm, a cued recall test follows a recognition test. Large amounts of data have revealed a lawful moderate dependence between recognition and cued recall. TECO (Sikström, 1996b), a general connectionist theory of memory, has been

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Some of the objections to life-extension stem from a concern with overpopulation. I will show that whether or not the overpopulation threat is realistic, arguments from overpopulation cannot ethically demand halting the quest for, nor access to, life-extension. The reason for this is that we have a right to life, which entitles us not to have meaningful life denied to us against our will and which

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Millimeter-wave cellular communication requires beamforming procedures that enable alignment of the transmitter and receiver beams as the user equipment (UE) moves. For efficient beam tracking it is advantageous to classify users according to their traffic and mobility patterns. Research to date has demonstrated efficient ways of machine learning based UE classification. Although different machine

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Incorporating time as a unit of analysis can enrich the study of agency by showing the specific ways in which actors are temporally constrained when responding to economic disturbances. In this paper, this is done by examining how the behavior of actors is affected by timing norms such as term limits that may be associated with an actor's position, as for example, an elected mayor or university vi

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The 1.87–1.84 Ga Black Hills dike swarm of the Kalahari craton (South Africa) is coeval with several regional magmatic provinces used here to resolve the craton’s position during Columbia assembly. We report a new 1850 ± 4 Ma (U-Pb isotope dilution–thermal ionization mass spectrometry [ID-TIMS] on baddeleyite) crystallization age for one dike and new paleomagnetic data for 34 dikes of which 8 have