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An investigation into the implementation state of open standards in software is currently ongoing through the ISPRS/EuroSDR 'GeoBIM benchmark 2019' initiative, which kicked off earlier this year. The benchmark activity provides a way of assessing and comparing the functionality of different software packages in GIS and BIM in terms of their ability to handle standardised data (IFC and CityGML) and
For a long time, the predominant method for detection of quick clay in Sweden has been to take undisturbed samples and to perform fall-cone tests on the clay in its undisturbed and remoulded state. In connection with a large stability investigation covering both sides of the Gota River, from the lake Vanern to the city of Gothenburg, the usefulness of CPTu and static pressure sounding for mapping
Emerging nonlinear optical spectroscopies enable deeper insight into the intricate world of interactions and dynamics of complex molecular systems. 2D electronic spectroscopy appears to be especially well suited for studying multichromophoric complexes such as light-harvesting complexes of photosynthetic organisms as it allows direct observation of couplings between the pigments and charts dynamic
One extra chromosome copy (i.e., trisomy) is the most common type of chromosome aberration in cancer cells. The mechanisms behind the generation of trisomies in tumor cells are largely unknown, although it has been suggested that dysfunction of the spindle assembly checkpoint (SAC) leads to an accumulation of trisomies through failure to correctly segregate sister chromatids in successive cell div
This study, which is the first and main part of a two-volume work, is concerned with the history and philology of original and translated works Adversus Iudaeos circulating among the Eastern Slavs from the baptism of Rus' c.988 till the early 16th century. Excluded is the literature of Lithuanian Ruthenia from the 14th century onwards. On the material of 11–15th-century MSS the dissemination of th
Background Quadrivalent human papillomavirus (HPV types 6/11/16/18) L1 VLP vaccine is highly effective in preventing HPV 6/11/16/18-related cervical and external genital disease. Herein, we evaluated the impact of the quadrivalent HPV 6/11/16/18 L1 VLP vaccine on prevention of HPV-associated cervico-genital lesions in a broad population of sexually active European women. Methods Female subjects (N
The four major autoantigens (IA-2, IA-2 beta, GAD65 and insulin) of type 1 diabetes are all associated with dense core or synaptic vesicles. This raised the possibility that other secretory vesicle-associated proteins might be targets of the autoimmune response in type 1 diabetes. To test this hypothesis 56 proteins, two-thirds of which are associated with secretory vesicles, were prepared by in v
This study aimed to determine the effects of advanced glycation end products (AGEs) on endothelial cytoskeleton morphology and permeability, and to detect the underlying signaling mechanisms involved in these responses. Cultured endothelial cells (ECs) were exposed to AGE-modified human serum albumin (AGE-HSA), and EC cytoskeletal changes were evaluated by observing fluorescence of F-actin followi
Mate choice for major histocompatibility complex (MHC) compatibility has been found in several taxa, although rarely in birds. MHC is a crucial component in adaptive immunity and by choosing an MHC-dissimilar partner, heterozygosity and potentially broad pathogen resistance is maximized in the offspring. The MHC genotype influences odour cues and preferences in mammals and fish and hence olfactory
Phosphor thermometry is applied for the first time in a large-bore two-stroke diesel engine. The work proves the practicality of phosphor thermometry in large-bore engines. The experiments were conducted on the MAN 4T50ME-X marine research engine equipped with an optical cylinder head. By employing a thin surface coating of CdWO4 phosphor, cycle resolved temperature measurements of the cylinder wa
Microelectronics promises a high component density and low power dissipation to embedded systems. Unfortunately such a component will always suffer from various error types that make the chip respond differently from its functional simulation. This is especially true for Cellular Neural Networks (CNN), which makes the determination of robust, low-precision parameters to guarantee small footprint a
Linear pi-conjugated oligomers have been widely investigated, but the behavior of the corresponding cyclic oligomers is poorly understood, despite the recent synthesis of pi-conjugated macrocycles such as [n]cycloparaphenylenes and cyclo[n]thiophenes. Here we present an efficient template-directed synthesis of a pi-conjugated butadiyne-linked cyclic porphyrin hexamer directly from the monomer. Sma
Using a combination of experimental and theoretical techniques, we show that a thin RhO2 surface oxide film forms prior to the bulk Rh2O3 corundum oxide on all close-packed single crystal Rh surfaces. Based on previous reports, we argue that the RhO2 surface oxide also forms on vicinal Rh surfaces as well as on Rh nanoparticles. The detailed structure of this film was previously determined using U
In this paper, we applied Bayesian multi-layer perceptrons (MLP) using the evidence procedure to predict malignancy of ovarian masses in a large (n = 1,066) multi-centre data set. Automatic relevance determination (ARD) was used to select the most relevant inputs. Fivefold cross-validation (5CV) and repeated 5CV was used to select the optimal combination of input set and number of hidden neurons.
Popular Abstract in Swedish Syftet med denna avhandling är att studera den sydhalländska stickningsindustrins framväxt, utveckling och organisation under tidigmodern tid. Denna protoindustriella verksamhet bedrevs i godsbygd i huvudsak på förlagsbasis. Tidigt spelade Wallens gods i Våxtorps socken en aktiv roll i verksamheten. Under 1700-talets senare hälft organiserades stickningsindustrin av förThe aim of this dissertation has been to examine the growth, development, and organisation of the knitting industry in southern Halland during early modern times. This proto-industrial enterprise was conducted primarily via a putting-out system in the goods districts. Wallen's estate in Våxtorp parish played an active role in the enterprise already from an early stage. During the latter half of th
The paper presents the major findings from the three evacuation experiments being part of the Swedish METRO research project. In the evacuation experiments; the small, medium and full-scale experiments, investigations were carried out with the purpose to study how train passengers safely can be evacuated in case of a fire emergency. In addition to determine flow rates, the walking velocity and wal
The main objective of this PhD thesis, "An Aesthetics of Sexual Difference? On Art and Artistry in Swedish Handicraft of the 1920s and 1990s", is to investigate the field of handicraft in relation to a wider field of cultural production. Its aim is to contribute to a mapping of interrelated outlines of handicraft and art based on empirical studies of artistic creation in two local Swedish handicra
The type I interferon system genes IKBKE and IFIH1 are associated with the risk of systemic lupus erythematosus (SLE). To identify the sequence variants that are able to account for the disease association, we resequenced the genes IKBKE and IFIH1. Eighty-six single-nucleotide variants (SNVs) with potentially functional effect or differences in allele frequencies between patients and controls dete
Cyclooxygenase-2 (COX-2) is an inducible enzyme that drives inflammation and is the therapeutic target for widely used nonsteroidal antiinflammatory drugs (NSAIDs). However, COX-2 is also constitutively expressed, in the absence of overt inflammation, with a specific tissue distribution that includes the kidney, gastrointestinal tract, brain, and thymus. Constitutive COX-2 expression is therapeuti
Background Comparison of patients with coronary heart disease and controls in genome-wide association studies has revealed several single nucleotide polymorphisms (SNPs) associated with coronary heart disease. We aimed to establish the external validity of these findings and to obtain more precise risk estimates using a prospective cohort design. Methods We tested 13 recently discovered SNPs for a
