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In this 2 hour workshop the experiences of the geographic data domain will be shared with the open data research & education community to promote and strengthen active innovative learning and teaching in both worlds. The domain of geographic data can be considered as one of the front running in open data. Over the past two decades, many geographic datasets in Europe became available as open da
Objectives: To study how radiologists’ perceived ability to interpret digital mammography (DM) images is affected by decreases in image quality. Methods: One view from 45 DM cases (including 30 cancers) was degraded to six levels each of two acquisition-related issues (lower spatial resolution and increased quantum noise) and three post-processing-related issues (lower and higher contrast and incr
Permafrost extends 40% of the Qinghai-Tibet Plateau (QTP), a region which contains the headwaters of numerous major rivers in Asia. As an aquiclude, permafrost substantially controls surface runoff and its hydraulic connection with groundwater. The freeze–thaw cycle in the active layer significantly impacts soil water movement direction, velocity, storage capacity, and hydraulic conductivity. Unde
Pharmaceuticals that are not completely metabolized in the human body are excreted in wastewater and may find their way into surface waters, where they can have harmful effects on aquatic fauna and flora. The implementation of ozonation at wastewater treatment plants (WWTPs) can reduce the amount of pharmaceuticals discharged to the environment. Despite the technology readiness level of ozone trea
Nondestructive imaging with both a large field of view and a high spatial resolution is crucial to understand complex materials and processes in science and technology. X-ray ptychography can provide highest spatial resolution but is limited in the field of view by the acquisition time and coherent flux at modern x-ray sources. By multi-beam ptychography, the sample can be imaged in parallel by se
Orientation towards application, transdisciplinarity and social distribution are prominent ideas when policy prescribes how to conduct research on complex, real-world issues. Issues dealt with in ageing research are both epistemologically complex and politically contentious. By using the metaphor of ‘travelling ideas,' we have followed these ideas on their journey into 17 approved grant proposals
Modelling capabilities have drastically improved in the last decade. However, in most of the cases the fire response of building elements is predicted by fitting input material properties to the models in order to match test data. This paper presents models developed to predict the unexposed side temperature of stone wool layered composites with stainless steel or gypsum claddings exposed to sever
Background/Aims Prematurely born infants undergo costly, stressful eye examinations to uncover the small fraction with retinopathy of prematurity (ROP) that needs treatment to prevent blindness. The aim was to develop a prediction tool (DIGIROP-Screen) with 100% sensitivity and high specificity to safely reduce screening of those infants not needing treatment. DIGIROP-Screen was compared with four
One of the most common practical inventory control problems is considered. A single-echelon inventory system is controlled by a continuous review (R,Q) policy. The lead-time demand is normally distributed. We wish to minimize holding and ordering costs under a fill rate constraint. Although, it is not especially complicated to derive the optimal solution, it is much more common in practice to use
The capability of retrieving spectral information from line shapes recorded by two-tone frequency-modulation spectroscopy (TTFMS) is investigated. A TTFMS theory accounting for dispersion and nonlinear distortion of diode laser frequency modulation response is presented. The adequacy of the theory for a detailed modeling of line shapes recorded with high resolution is examined. An extensive error
Preclinical studies support an anticancer effect of statin drugs, yet epidemiologic evidence remains inconsistent regarding their role in breast cancer primary prevention. Here, we report an updated analysis of the association between statin use and breast cancer incidence in the Nurses' Health Study (NHS) cohort. Postmenopausal NHS participants without a cancer history were followed from 2000 unt
Abstract in FrenchDecay-prediction models can be used to predict the service life of wooden components. However, knowledge of how the material climate, i.e. moisture content and material temperature, varies with time is required. A reliable material climate prediction model is therefore crucial in situations when measurements are not viable. The aim of this paper is to develop and assess the perfo
Follow-up of endovascular aneurysm repair (EVAR) with life-long computed tomography angiography (CTA) surveillance exposes patients with impaired renal function to repeated risks of contrast medium-induced nephropathy (CIN).
BACKGROUND: The genes caspase-8 (CASP8) and caspase-10 (CASP10) functionally cooperate and play a key role in the initiation of apoptosis. Suppression of apoptosis is one of the major mechanisms underlying the origin and progression of cancer. Previous case-control studies have indicated that the polymorphisms CASP8 D302H and CASP10 V410I are associated with a reduced risk of breast cancer in the
Aims: This study summarises the health-related quality of life (HRQOL) scores and absenteeism caused by sinus problems in patients awaiting surgery with the diagnoses recurrent acute rhinosinusitis (RARS), chronic rhinosinusitis with nasal polyps (CRS+NP) or CRS without nasal polyps (CRS-NP), in a prospective multi-centre study. Methodology: Two hundred and seven patients with RARS, CRS+NP or CRS-
The aim of our study was to test the hypothesis that administration of Regenerating islet-derived protein 3α (Reg3α), a protein described as having protective effects against oxidative stress and anti-inflammatory activity, could participate in the control of glucose homeostasis and potentially be a new target of interest in the treatment of type 2 diabetes. To that end the recombinant human Reg3α
