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Several stars show deep transits consistent with discs of roughly seen at moderate inclinations, likely surrounding planets on eccentric orbits. We show that this configuration arises naturally as a result of planet-planet scattering when the planets possess satellite systems. Planet-planet scattering explains the orbital eccentricities of the discs' host bodies, while the close encounters during

Background: A diagnosis of prostate cancer (PC) may cause psychosocial distress not only in a man but also in his intimate partner. However, long-term risks of depression, anxiety, or suicide in partners of men with PC are largely unknown. Methods: A national cohort study was conducted of 121 530 partners of men diagnosed with PC during 1998-2017 and 1 093 304 population-based controls in Sweden.

Young people have been prominent climate advocates globally and they are also becoming increasingly visible in global climate politics. They have participated in Conferences of the Parties (COPs) to the United Nations Framework Convention on Climate Change (UNFCCC) since COP1 in 1995. While recent studies have started to examine the representativeness and participation of youth at the COPs, we sti

This book challenges earlier understandings of early modern dissertations as unimaginative academic exercises. It argues for their continuous importance in scholarly and scientific discourse, and describes the richness and diversity of their subjects and themes. The book contains a complete catalogue of the almost 20,000 Swedish dissertations defended in Uppsala, Lund and Åbo, 1600 to 1820. The ca

This chapter explores the relationship between long-term exposure to neighborhood income inequality and adult mortality in Landskrona during a period of declining economic disparities. Using geocoded data from 1939 to 1967, the authors examine three interconnected hypotheses concerning income inequality and longevity. The analysis considers spatial changes in neighborhood inequality over time and

Attempts to measure social mobility before the twentieth century are frequently hampered by limited data. In this paper, we use a new source – annual, matched tax censuses over more than 70 years – to calculate intragenerational income mobility within a preindustrial, settler society, the Dutch and British Cape Colony at the southern tip of Africa. Our unique source allows us to measure income mob

Presents a two-dimensional stochastic convection-diffusion model for use in real-time prediction of the space-time rainfall structure in urban areas. The model is used to parameterize the rainfall intensity from individual rain cells. Especially, we are interested to quantify the rainfall intensity resulting from different separable components of the rain cell. This is done by a Lagrangian approac

Anastomotic defect (AD) after esophagectomy can lead to severe complications with need for surgical or endoscopic intervention. Early detection enables early treatment and can limit the consequences of the AD. As of today, there are limited methods to predict AD. In this study, we have used microdialysis (MD) to measure local metabolism at the intrathoracic anastomosis. Feasibility and possible di

Brain tumours are among the most common cancer diagnoses in paediatrics. Children with brain tumours are at risk of developing sleep problems because of direct and indirect effects of the tumour and its treatment, in addition to psychosocial and environmental factors. Sleep has an important role in physical and psychological wellbeing, and sleep problems are associated with many adverse outcomes.

ObjectivesAn endovascular aneurysm repair (EVAR) graft is a catheter-implanted vascular prosthesis and is the preferred treatment for patients with aortic aneurysm. If an EVAR graft becomes the focus of infection, the treatment possibilities are limited as it is technically difficult to remove the graft to obtain source control. This study examines whether Pseudomonas aeruginosa and Staphylococcus

Responding to perceived threats is energetically expensive and can require animals to curtail somatic repair, immunity, and even reproduction to balance energy ledgers. In birds and mammals, energetic demands of thermoregulation are often immense, yet whether homeostatic body temperatures are also compromised to aid the stress response is not known. Using data sourced from over 60 years of literat

Atherosclerosis, the underlying pathology of cardiovascular diseases such as myocardial infarction and ischemic stroke, is characterized by chronic inflammation. T cells are present in atherosclerotic plaques and have been implicated in its pathogenesis. This thesis describes studies exploring both the regulation of T cells in atherosclerosis as well as immunomodulatory therapeutics. To study the

BACKGROUND: The study aimed to show the relationship between a large number of circulating metabolites and subsequent cardiovascular disease (CVD) and subclinical markers of CVD in the general population. METHODS AND RESULTS: In 2278 individuals free from CVD in the EpiHealth study (aged 45–75 years, mean age 61 years, 50% women), 790 annotated nonxenobiotic metabolites were measured by mass spect

The preservation of labile biomolecules presents a major challenge in chemistry, and deep eutectic solvents (DESs) have emerged as suitable environments for this purpose. However, how the hydration of DESs impacts the behavior of proteins is often neglected. Here, we demonstrate that the amino acid environment and secondary structure of two proteins (bovine serum albumin and lysozyme) and an antib

BACKGROUND: The EAT-Lancet Commission proposed a globally environmentally sustainable dietary pattern featuring mainly plant-based foods in 2019. However, evidence on this dietary pattern in preventing coronary events is minimal.OBJECTIVE: We aimed to examine the association between the EAT-Lancet diet and risk of coronary events.METHODS: The Malmö Diet and Cancer cohort study (recruited between 1

Aqueous dispersions of charged-neutral block copolymers (poly(acrylamide)-b-poly(acrylate)) complexed with an oppositely charged surfactant (dodecyltrimethylammonium) have been prepared by different approaches: the simple mixing of two solutions (MS approach) containing the block copolymer and surfactant, with their respective simple counterions, and dispersion of a freeze-dried complex salt prepa

Introducing the dragon simulation project, we present direct N-body simulations of four massive globular clusters (GCs) with 106 stars and 5 per cent primordial binaries at a high level of accuracy and realism. The GC evolution is computed with nbody6++gpu and follows the dynamical and stellar evolution of individual stars and binaries, kicks of neutron stars and black holes (BHs), and the effect

Bacterial endotoxin is a potent inflammatory antigen abundant in the human intestine. Endotoxins circulate in the blood at low concentrations in all healthy individuals. Elevated levels of circulatory endotoxins may cause inflammation with the development of chronic disease, either affecting metabolism, neurological disease, or resistance to viral and bacterial infections. The most important endot