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This paper presents a novel approach for the elaboration of an integration strategy for controls and computing systems at large particle accelerator based research facilities. The approach is applied in a specific case study conducted at the world-leading neutron science facility European Spallation Source (ESS). First, an introduction to the term 'integration' in the Systems Engineering literatur
OBJECTIVE: Sleep disturbances and alterations of diurnal endocrine rhythms are associated with increased risk of type 2 diabetes (T2D). We previously showed that young men born small for gestational age (SGA) and with increased risk of T2D have elevated fat and decreased glucose oxidation rates during nighttime. In this study, we investigated whether SGA men have an altered diurnal profile of horm
In 2014 the Nordic Council of Ministers initiated a new bioeconomy project: “Test centers for green energy solutions – Biorefineries and Business needs”. The purpose was to strengthen green growth in the area of the bioeconomy by analyzing and mapping the current status of the bioeconomy in the Nordic countries and identify potentials and obstacles, needs and opportunities. Based on this a set of
An important factor for health is the possibility to be active and mobile. To make this possible various kinds of support are needed. Integrating geographical information systems technology and user experiences is important in the development of more user-friendly positioning devices. The Lighthouse Alarm and Locator trial aimed to test a new mobile alarm system with additional functionality such
Cellular adaptation to diminished tissue oxygen tensions, hypoxia, is largely governed by the hypoxia inducible transcription factors, HIF-1 and HIF-2. Tumor hypoxia and high HIF protein levels are frequently associated with aggressive disease. In recent years, high tumor cell levels of HIF-2 and the oxygen sensitive subunit HIF-2alpha have been associated with unfavorable disease and shown to be
Background and Aims: Small-bowel bleeding is the primary indication for capsule endoscopy (CE). Many experts advocate a "watch-and-wait" policy in negative CE. This meta-analysis examines the odds of rebleeding after negative index CE and the impact on long-term follow-up. Methods: A comprehensive literature search identified articles examining the rebleeding rate after negative CE. Demographic an
Differential equations with infinitely many derivatives, sometimes also referred to as “nonlocal” differential equations, appear frequently in branches of modern physics such as string theory, gravitation and cosmology. We properly interpret and solve linear equations in this class with a special focus on a solution method based on the Borel transform. This method is a far-reaching generalization
Interference effects in quantum dots between different transport channels can lead to a strong suppression of conductance, which cuts like a canyon through the common conductance plot [Phys. Rev. Lett. 104, 186804 (2010)PRLTAO0031-900710.1103/PhysRevLett.104.186804]. In the present work we consider the thermoelectric transport properties of the canyon of conductance suppression using the second-or
Research has shown that people with psychiatric disabilities who attend a day center rate their satisfaction with daily occupations equally in comparison with non-attendees. The current study investigates which occupations the target group performs and also differences in occupational choices between attendees and non-attendees. Reported occupations were analyzed with content analysis. Day center
This study examines the relationship between trade and the quality of economic institutions under different political institutions. It uses panel data of 138 countries from 1984 to 2010 and employs instrumental variables and identification through heteroscedasticity to mitigate the problem of endogeneity. The findings suggest that the effect of trade on economic institutions reduces significantly
Purpose– This paper aims to present a study of the role of prior start‐up experience as a source of learning in the entrepreneurial process. Three learning outcomes are examined with respect to a comparison between habitual and novice entrepreneurs: skills for coping with liabilities of newness, preference for effectual reasoning, and attitudes towards failure.Design/methodology/approach– This is
