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Parkinson’s disease (PD) is a movement disorder of the brain which is hallmarked by the presence of large protein-rich cytoplasmic aggregates, called Lewy bodies (LBs), in the neurons. The protein α-synuclein (α-syn) is abundant in these aggregates, and can itself form aggregates. Several mutations linked to α-syn are also linked to an increased risk of contracting PD. In healthy neurons, the chap

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The study aims to uncover the discursive elements at work in Swedish public discourse on antisemitism. The study situates the International Holocaust Remembrance Alliance definition of antisemitism in relation to Swedish discourse with the aim of measuring their congruence. A final aim is to uncover if the broadening of the term has led to marginalisation of those seen as problematic – constitutiv

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Pyruvate is one of the main molecules needed for the citric acid cycle, which produces energy in the form of ATP. The citric acid cycle reaction occurs in the mitochondrial matrix, and for pyruvate to participate in the reaction, it needs to be transported from the cytosol across the mitochondrial membranes into the mitochondrial matrix. A special membrane protein called the mitochondrial pyruvate

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This paper investigates two facets of corporate cash holdings in firms listed on the Stockholm Stock Exchange over the period 2001−2020. Firstly, I examine the determinants of corporate cash holdings. I find that firms with more investment opportunities and smaller firms tend to hold more cash. Firms with controlling shareholders and firms with high institutional block holdings tend to hold less c

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This study examines how changes in market structures, especially market concentration and consolidations, within the Swedish livestock sector have affected animal welfare. Through a historical narrative analysis, structural change and its drivers are identified. Subsequently, an outline of animal welfare legislation is covered, comparing the EU and the Swedish context, and governing forces in anim

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Title: Performance Measurement Systems, Middle Managers, and the Fight over Control Seminar Date: June 2nd, 2023 Course: Business Administration: Bachelor’s degree project in organization. Undergraduate level, 15 credits. Authors: Nicole Kronkvist, Fritjof Jansson and Maja Muscat Scerri Supervisor: Johan Jönsson Five Keywords: Performance Measurement Systems, Expectancy Theory, Middle Manage

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This paper aims to better understand how contraceptive uptake is influenced by both individual and environmental factors, specifically in sub-Saharan Africa, by comparing Uganda and Kenya as examples of different policy environments. Implementing a literature review and statistical regression, this paper analyses how various factors (including indicators of gender equality, family planning exposur

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The accumulation of carbon (C) within boreal forest biomass is an important component of the global carbon cycle. Whilst it is understood that old forests contain a large carbon stock, the continued sequestration of carbon in these forests is debated. Swedish forests today are intensively managed as even-aged monocultures with short rotation times and have historically been managed through selecti

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Vegetation indices derived from remotely sensed optical data are commonly used for crop monitoring in precision agriculture, but their information capability can be hindered by the presence of clouds. Consequently, areas with frequent cloud cover like the southwest of Sweden may have limited access to usable optical data. Nonetheless, the addition of synthetic aperture radar (SAR) data can provide

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Recent decades have witnessed an innovation in genetics and biomedical practices, shifting the practice from treatment to prevention. Testing healthy individuals for genetic inherited diseases has now become increasingly common, preventing potential disease by offering early screenings, medication, or potentially surgery, reducing the genetic risk from developing into disease. Though, social scien

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Dark matter has an important role in our Universe, especially in galaxy formation and evolution, but there are many theoretical models that attempt to describe it and to find out which one, if any, are correct we must test them. Testing a theoretical model of this nature at a galactic scale must and has been done using computational methods through simulations, but this has revealed more complicat

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A hydraulic system is designed to transport fluid power over large distances, from pumps to actuators where the fluid power is transformed to mechanical power. The submarines, built and designed by Saab Kockums, utilises such systems. There are, however, challenges as the hydraulic pumps consume much energy, and the system accumulators command significant space. As both energy and space are limite

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This thesis analyzes schoolchildren’s mental health development in five mental health-related variables when they gain internet access through 3G networks. A unique panel dataset using the HBSC with country-level 3G coverage is constructed. Using a TWFE strategy to estimate the effect on the five outcome variables, a decrease in mental health is found for both female and male children. The results

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The aim of this study was to investigate how adult attachment styles and emotional intelligence impact decision-making styles. An online survey was distributed to individuals aged 18 years or older (N =110). The survey included three instruments; the Adult Attachment Scale (AAQ), Wong & Law Emotional Intelligence Scale (WLEIS), and the General Decision-Making Style (GDMS) questionnaire, along

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This thesis explores the complex relationship between crime and development, focusing on how this relationship is understood in current literature. Through synthesising existing literature, empirical evidence, and theoretical frameworks such as modernisation theory, strain theory, and social disorganisation theory, it aims to offer a nuanced understanding of this nexus. The systematic literature r

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This thesis examines the impact of shareholder activism on the annual stock returns of targeted companies. Utilizing a dataset of activist campaigns from the FactSet SharkWatch 50 database, covering the period from 2005 to 2021, we investigate whether the presence of activist investors leads to enhanced stock performance. Our empirical analysis, employing an event study design, reveals a significa

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This thesis explores the potential of incorporating Artificial Intelligence (AI) into User Experience (UX) Research Operations (ResearchOps) within an organisational context. Design Science Research (DSR) was employed to develop and evaluate a method that incorporates AI to enhance user research activities. The research involved conducting qualitative interviews with UX professionals at Alpha to u

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There is uncertainty about whether AI-generated output can and should be protected under EU copyright law and, in that case, who should obtain the rights. This thesis examines this legal issue by interpreting the legal text especially the InfoSoc Directive, case law and by considering legal scholarships. It has been established in the thesis that an AI-generated output can be considered protectabl

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Introduction: Proteins encoded by Fanconi anemia (FA) and/or breast cancer (BrCa) susceptibility genes cooperate in a common DNA damage repair signaling pathway. To gain deeper insight into this pathway and its influence on cancer risk, we searched for novel components through protein physical interaction screens. Methods: Protein physical interactions were screened using the yeast two-hybrid syst