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The aim of this study was to determine in patients with HCV genotype 2 or 3 the performance at week 4 of two assays with different sensitivities for HCV RNA detection, for the prediction of SVR and stratification for treatment duration (14 and 24 weeks). Recruitment was from two trials comparing 14 and 24 weeks treatment to patients with rapid virological response (RVR) (n = 550). RVR was original
Birds are assumed to use half of their cones (double cones) to detect fine spatial detail while their other half (single cones) is used for color vision. However, the spatial resolution of the color pathway in birds has never been studied. We determined the spatial contrast sensitivity to achromatic and isoluminant red-green and blue-green color gratings in budgerigars (Melopsittacus undulatus). C
The hyaluronan (HA)-rich pericellular coat (PCC) enveloping most mammalian cells plays a vital role in biological processes such as cell adhesion, proliferation, motility and embryogenesis. In particular its presence on chondrocytes, which live in the load-bearing cartilage, has a wide range of implications in diseases such as osteoarthritis, highlighting its mechanical role in living organisms. D
This paper looks into indigenous Aymara notions of ‘the strange’ and ‘the proper’ and examines how such notions are articulated in an indigenous criticism of a persistently colonial modernity. Such criticism is double-edged. On the one hand, it is articulated in a mythological idiom referring to conceptions of profound cosmological import and this paper delves into how such criticism is grounded i
Abstract Background. Proteinuria is the hallmark of glomerular disease and non-selective proteinuria is often associated with progression to renal failure. The predictive value of urine IgG excretion was studied comprehensively in patients with nephrotic syndrome. In the present follow-up study, we examine the predictive value of IgG-uria in patients with idiopathic glomerular diseases with a wide
A systemic nature of allergic diseases has been hypothesized. As part of this discussion, we studied if adolescent allergic wheeze and increasing combinations of allergic organ involvements (lung, nose and skin) would also increase the reporting of other health problems (headache, muscle pain and abdominal pain). In addition, we studied if parental asthma was associated with adolescent clustering
Background: The prevalence of blindness and visual impairment from glaucoma is influenced by the criteria used to define these entities, which differ between countries and regions, as well as among published reports. The objective of the present study was to ascertain the extent to which different criteria of blindness and visual impairment influence estimates of the number of patients classified
Even though a number of studies have shown that UV-B radiation inhibits plant growth and regulates the cell cycle progress, little is known about the molecular and cellular mechanisms. Here, we developed a synchronous root-tip cell system to investigate expression changes of cell cycle marker genes and DNA damage under UV-B radiation. Expression analysis of cell cycle marker genes revealed that G1
Rationale and Objectives: To compare the ability of normalized versus non-normalized metabolite ratios to differentiate recurrent brain tumor from radiation injury using magnetic resonance spectroscopy (MRS) in previously treated patients. Materials and Methods: Twenty-five patients with previous diagnosis of primary intracranial neoplasm confirmed with biopsy/resection, previously treated with ra
Alpha-1-antitrypsin (AAT) is a glycoprotein synthesised in the liver. Its main role is to protect lung tissue from destruction by neutrophil elastase. In severe (PiZZ) AAT deficiency, there is an increased risk of emphysema, especially in smokers. The deficiency is caused by the retention and aggregation by polymerization of the AAT molecules in the liver, which increases the risk of neonatal chol
The Mifflin meteorite fell on the night of April 14, 2010, in southwestern Wisconsin. A bright fireball was observed throughout a wide area of the midwestern United States. The petrography, mineral compositions, and oxygen isotope ratios indicate that the meteorite is a L5 chondrite fragmental breccia with light/dark structure. The meteorite shows a low shock stage of S2, although some shock-melte
To investigate how far the GW approximation can treat systems with strong on-site correlations, we perform calculations of the self-energies and spectral functions of alpha-and gamma-Ce within the GW approximation. For this strongly correlated material, the screened interaction exhibits a complex and rich structure which is attributed to strong particle-hole transitions involving localized 4f stat
PURPOSE. To estimate the rate of visual field progression in open-angle glaucoma (OAG) subjects, by using data from population-based cross-sectional studies. METHODS. Subjects with OAG were identified in nine surveys of randomly sampled populations using standard criteria for glaucomatous optic neuropathy. Subjects were of European, African, Chinese, and Hispanic ethnicity. The measure of OAG dama
A series of aromatic multiblock copolymers based on alternating segments of hydrophilic sulfonated polysulfone (PSU) and hydrophobic polyfluoroether (PFE) were prepared and characterized as proton exchange membranes. PSU precursor blocks were synthesized by polycondensation of dichlorodiphenylsulfone and resorcinol, and PFE precursor blocks were prepared by combining decafluorobiphenyl and isoprop
Background Primary Sjogren's syndrome (pSS) is an autoimmune rheumatic disease mainly characterised by focal mononuclear cell infiltration in the salivary and lacrimal glands, and by the symptoms xerostomia and keratoconjunctivitis sicca. Germinal centre-like structures (GC) are found in the minor salivary glands of approximately 25% of patients. In this study, we aimed to assess genetic variation
We have re-investigated the organization of ocelli in honeybee workers and drones. Ocellar lenses are divided into a dorsal and a ventral part by a cusp-shaped indentation. The retina is also divided, with a ventral retina looking skywards and a dorsal retina looking at the horizon. The focal plane of lenses lies behind the retina in lateral ocelli, but within the dorsal retina in the median ocell
Magnetic shape-memory Heusler alloys are multiferroics stabilized by the correlations between electronic, magnetic, and structural order. To study these correlations we use time-resolved x-ray diffraction and magneto-optical Kerr effect experiments to measure the laser induced dynamics in a Heusler alloy Ni2MnGa film and reveal a set of time scales intrinsic to the system. We observe a coherent ph
The transfer of 210Po and 210Pb between various compartments in the terrestrial environment has been analysed by using various published data. The average activity concentration of 210Po in soil is 61 ± 14 Bq.kg-1 d.w. with a median (50%) value of 44 Bq.kg-1 d.w. Ground water concentrations of 210Po in drilled wells might be as high as 6.5 Bq/l. But in regular drinking water it is just about 3-5
A model for the adsorption of colloidal particles on a planar surface is analyzed by using a thermodynamic chemical equilibrium model and Monte Carlo simulations. Central to this investigation are that (i) particles and surface are considered to be of the same material and (ii) the particle-surface and particle-particle interactions are related using the Derjaguin approximation using a surface-sur
