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Feasibility of noninvasive transthoracic echocardiography/Doppler measurement of coronary flow reserve in left anterior descending coronary artery in patients with acute coronary syndrome: A new technique tested in clinical practice

Objective: The aim of this study was to test the feasibility and accuracy of transthoracic Doppler echocardiography measurement of coronary flow reserve (CFR) in the left anterior descending coronary artery (LAD) territory in the clinical setting of the acute coronary syndrome. Methods: Transthoracic Doppler echocardiography measurements of CFR were made in 42 consecutive patients in the distal LA

Reswelling of polyelectrolyte hydrogels by oppositely charged surfactants

The interactions between charged alkylacrylamide gels of varying hydrophobicity and charge density and the oppositely charged surfactant hexadecyltrimethylammonium (C(16)TA(+)) have been investigated to determine the conditions necessary to induce excess surfactant binding (beyond charge neutralization) and resolubilization of the polymer-surfactant complex. In all cases, an initial gel collapse o

Structure and thermodynamics of protein-polymer solutions: Effects of spatially distributed hydrophobic surface residues

Protein-polymer association in solution driven by a short-range attraction has been investigated using a simple coarse-grain model solved by Monte Carlo simulations. The effect of the spatial distribution of the hydrophobic surface residues of the protein on the adsorption of weakly hydrophobic polymers at variable polymer concentration, polymer length, and polymer stiffness has been considered. S

Monoclonal Antibody against T-Cell Receptor alphabeta Induces Self-Tolerance in Chronic Experimental Autoimmune Encephalomyelitis.

The therapeutic effect of monoclonal antibody (H57-597 MoAb) against T-cell receptor (TCR) alpha beta has been investigated on MOG(35-55)-induced experimental autoimmune encephalomyelitis (EAE), as a model system for T-cell-mediated chronic inflammation in the central nervous system (CNS). Short-term administration of the anti-TCR alpha beta immediately after immunization protected the mice from E

Human impact on the fish diversity in the four largest lakes of Sweden

The four largest Swedish lakes, Vanern, Vattern, Malaren, Hjalmaren, host important commercial fisheries for char, salmon, trout, whitefish, vendace (cisco), perch, pike-perch, pike and eel, i.e. highly diverse biological resources. Case studies illustrate physical, chemical and biological impacts on some of these commercial species caused by constructions of dams and ship canals, eutrophication,

Hydrogen exchange and hydration dynamics in gelatin gels

Gelatin, derived from the collagen triple helix, is the most widely used functional biopolymer and a prototype for studies of physical gels. Gelatin gels have also served as models for soft biological tissue in efforts to elucidate the molecular basis of the magnetic relaxation phenomena that govern magnetic resonance image contrast. Yet, the microstructure, hydration, and magnetic relaxation beha

Stochastic Dominance And Conditional Expectation - An Insurance Theoretical Approach

We show that the relation of second order stochastic dominance, which has found widespread use in models of economic behavior under uncertainty, may be described in terms of conditional expectation. If a distribution G second order stochastically dominates another distribution F, then there are random variables g and f with distributions G and F, respectively, such that g can be obtained from f by

Responsive polymer gels: Double-stranded versus single-stranded DNA

Cross-linking of polyelectrolytes such as DNA gives gels that are osmotically highly swollen but contract upon addition of electrolytes and, in particular, upon association of oppositely charged cosolutes with the polyelectrolyte chain. The deswelling behavior of cross-linked DNA gels thus reflects the DNA-cosolute interactions and provides a basis for the development of responsive DNA formulation

A new nested polymerase chain reaction method very efficient in detecting Plasmodium and Haemoproteus infections from avian blood

Recently, several polymerase chain reaction (PCR)-based methods for detection and genetic identification of haemosporidian parasites in avian blood have been developed. Most of these have considerably higher sensitivity compared with traditional microscope-based examinations of blood smears. These new methods have already had a strong impact on several aspects of research on avian blood parasites.

The protective role of ROS in autoimmune disease.

For a long time, reactive oxygen species (ROS) produced by the phagocyte NADPH oxidase (NOX2) complex have been considered harmful mediators of inflammation owing to their highly reactive nature. However, there are an increasing number of findings suggesting that ROS produced by the NOX2 complex are anti-inflammatory and prevent autoimmune responses, thus challenging existing dogma. ROS might not

Johannes Klimakos, ur Den gudomliga Stegen

Swedish translation of steps 8, 13 and 14 of The Ladder of Divine Ascent by John Climacus. The translation is based upon Rader's edition reprinted in Migne's Patrologia Graeca, vol.88 (Paris, 1633).

The Process at Lund University, Sweden to make eLearning an integrated part of the educational system

Welcome to the e-manual on adult participation in universities! The manual is intended for managers, teachers and practitioners working with adults in universities. It may also be of interest to staff trainers and professional development co-ordinators, policy makers and administrators with an interest in adult higher learning, staff of national agencies who have a role to play in increasing adul