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Escherichia coli induces transuroepithelial neutrophil migration by an intercellular adhesion molecule-1-dependent mechanism

During bacterial infections at mucosal sites, neutrophils migrate to the mucosa and cross the epithelial barrier. We have examined neutrophil migration across Escherichia coli-stimulated uroepithelial cell layers in an attempt to more fully understand this process. Stimulation of uroepithelial cells with E. coli or interleukin-1α (IL-1α) induced transepithelial neutrophil migration in a time- and

Theoretical aspects of three-photon two-color ionization of xenon through ac-stark-shifted resonant rydberg states

We present a theoretical analysis of a recent experiment [J. Opt. Soc. Am. B 6, 1513 (1989)] on two-color threephotonionization of Xe through resonant even-parity Rydberg states. We calculate second-order ac-Stark shifts, two-photon Rabi frequencies, and ionization widths by using wave functions obtained from a multichannel quantum-defect-theory analysis of the Rydberg series in Xe. We perform a d

Bacterial-host interactions : Physiology and pathophysiology of respiratory infection

It has long been thought that respiratory infections are the direct result of acquisition of pathogenic viruses or bacteria, followed by their overgrowth, dissemination, and in some instances tissue invasion. In the last decades, it has become apparent that in contrast to this classical view, the majority of microorganisms associated with respiratory infections and inflammation are actually common

Human class II major histocompatibility antigen β-chains are derived from at least three loci

Class II antigens of the major histocompatibility complex (MHC) consist of two glycosylated, membrane-integrated polypeptide chains1. These cell surface-expressed molecules are involved in several immunobiological events involving cell-cell interactions2,3, most of which seem to require that genetically identical class II antigens, or other molecules controlled by the same region of the MHC, are e

Neutron stars in the galactic center

The Galactic Center is one of the most dense stellar environments in the Galaxy and is considered to be a plausible place to harbor many neutron stars. In this brief review, we summarize observational efforts in search of neutron stars within a few degrees about the Galactic Center. Up to 10% of Galactic neutron stars may reside in this central region and it is possible that more than a thousand n

Field trials with in-car speed limiter

Within the framework of the EU-financed project MASTER field trials with in-car speed limiter were carried out in three “region-typical” countries: Sweden, the Netherlands, and Spain. The speed limiter is an active gas pedal which provides a gas pedal counter-force whenever the driver tries to depress the pedal beyond a pre-set speed limit. Twenty subjects per country drove two times along the tes

On the metallicity dependence of the [Y/Mg]–age relation for solar-type stars

Several recent studies of solar twins in the solar neighbourhood have shown a tight correlation between various elemental abundances and age, in particular [Y/Mg]. If this relation is real and valid for other types of stars as well as elsewhere in the Galaxy, it would provide a very powerful tool to derive ages of stars without the need to resort to determining their masses (evolutionary stage) ve

Interaction sign patterns in biological networks: from qualitative to quantitative criteria

In stable biological and ecological networks, the steady-state influence matrix gathers the signs of steady-state responses to step-like perturbations affecting the variables. Such signs are difficult to predict a priori, because they result from a combination of direct effects (deducible from the Jacobian of the network dynamics) and indirect effects. For stable monotone or cooperative networks,

Place branding in the Øresund region : From a transnational region to a bi-national city-region

The Øresund Region that connects Copenhagen metropolitan area in Denmark and Southern Sweden is an interesting example of a European cross-border collaboration. In this article, the contemporary development of the region and the place branding process is described. The aim is to increase understanding of how a complex and bi-national place brand is developed in a process of continuous change due t

Generating Situational Authority Through Genre of Governance : A Case Study of Chinese Public Sectors’ Crisis Management Strategies

This study investigates how public sector organizations generate authority in social media crisis. Furthermore, it examines how genres of governance, namely genre chain and genre mixing, contribute to the generation of authority. On this basis of an interdisciplinary theoretical framework consisting of the concepts of “network governance” and “authority,” a genre analysis of 100 top forwarded post

Understanding the pulse of existence : An examination of capurro’s angeletics

The contribution of Rafael Capurro to the clarification of the uses of the concept of information has a conceptual as well a historical dimension; in this last sense, there are few philosophers of information that can follow the history of the concept of information in the works of the Classics with the accuracy and erudition of Capurro We find that his contribution embraces the following fields:

Multilingual literacy and the strategic development goal for quality education

Today’s communities are characterized by migration, transnationalism, and participation in the global economy, and many also have long local histories of linguistic diversity. Empowering individuals in these contexts means fostering the ability to use and expand their existing linguistic repertoires so they can take advantage of the social and economic opportunities afforded by contemporary life.