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The temperature dependence of the laminar burning velocity of ethanol flames

The Heat Flux method was extended for the first time towards liquid fuels and used to determine burning velocities under conditions when the net heat loss from the flame to the burner is zero. Non-stretched flames were stabilized on a perforated plate burner at 1 atm. Uncertainties of the measurements were analyzed and assessed experimentally. The overall accuracy of the burning velocities was est

Transplantation of lungs from a non-heart-beating donor

BACKGROUND: In animals, we have previously done successful lung transplantations using organs from non-heart-beating donors. We have also developed an ex-vivo system of assessing the function of such organs before transplantation. The next stage was to try the technique in human beings. Bearing in mind the sensitive ethical issues involved, our first aim was to find out what procedures would be ac

Microcirculation-derived factors in airway epithelial repair in vivo

Airway epithelial repair, by cell migration over a denuded, intact basement membrane, occurs rapidly in vivo. The present study examines microcirculation-derived factors in the reepithelialization process in the guinea pig. A well-defined tracheal zone was gently deepithelialized; no bleeding occurred and the basement membrane was left intact. Plasma exudation was visualized by use of iv colloidal

Curli, fibrous surface proteins of Escherichia coli, interact with major histocompatibility complex class I molecules

Curli are thin, coiled fibers expressed on the surface of Escherichia coli that bind several matrix and plasma proteins such as fibronectin, laminin, plasminogen, tissue plasminogen activator, and H-kininogen. In this work, we examined the interactions between curli-expressing E. coli and human major histocompatibility complex class I (MHC-I) and class II (MHC-II) molecules. Curliated E. coli was

Imbalanced serum IgG subclass pattern in toxic shock syndrome patients: deficiency of specific IgG1 and IgG4 subclass antibodies to toxic shock syndrome toxin 1

An imbalanced serum IgG subclass pattern was identified in 10 patients with toxic shock syndrome (TSS) showing remarkably low subclass levels of various combinations. IgG2 levels were significantly reduced as compared to normal controls. The IgG subclass-specificity of antibodies to toxic shock syndrome toxin (TSST-1) was investigated by a solid-phase radioimmunoassay. TSS-patients lacked pre-immu

Induction of IL-4 by platelet-activating factor

Platelet-activating factor (PAF) is a phospholipid inflammatory mediator which is synthesized by a variety of cells, including monocytes, endothelial cells, mast cells and neutrophils. PAF acts via a recently cloned PAF receptor, present on monocytes and endothelial cells, but not on non-activated lymphocytes. IL-4 is mainly produced by T lymphocytes, and belongs to the Th2 subset of T helper cell

Finemapping of the arthritis QTL Pia7 reveals co-localization with Oia2 and the APLEC locus.

In this study, we sought to determine the effect of the quantitative trait locus Pia7 on arthritis severity. The regulatory locus derived from the arthritis-resistant E3 rat strain was introgressed into the arthritis-susceptibility DA strain through continuous backcrossing. Congenic rats were studied for their susceptibility to experimental arthritis using pristane and adjuvant oil. In addition, c

Stages in the development of perceptual intersubjectivity

We offer an analysis of perceptual intersubjectivity (PI) in terms of two types (symmetric and asymmetric) and three levels: synchronous (SPI), coordinated (CPI) and reciprocal (RPI), defined on the basis of the observable behavior of the participants in a study of (non-verbal) social interaction. We hypothesize that the three levels constitute stages in the development and possibly evolution of h

The Maternal Group B Streptococcus Alpha-Like Protein Subunit Vaccine GBS-NN Targets Homotypic and Heterotypic Strains, Confers Opsonophagocytic Killing and Prevents in vitro Invasion of Human Epithelial Cells

Maternal vaccination, resulting in transfer of protective IgG across the placenta, represents a promising strategy to prevent neonatal disease caused by group B Streptococcus (GBS). The prototype vaccine GBS-NN, a fusion protein consisting of the N-terminal domains of the alpha-like protein (Alp) family members AlphaC and Rib, has been shown to display a good safety profile and to elicit a strong

Immunological aspects of latent tuberculosis infection during pregnancy

Pregnancy-induced immune modulation might lead to reactivation of latent tuberculosis infection (LTBI). This thesis explores aspects of immune-based LTBI diagnostics and how pregnancy affects the immune control of Mycobacterium tuberculosis (Mtb) infection. We studied a prospective cohort of women recruited during pregnancy in Ethiopia. LTBI testing was performed by quantification of interferon-γ

Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota

Popular Abstract in Swedish Att bär är nyttigt är ett påstående som de flesta känner igen. På butikshyllorna trängs våra nordiska bär med exotiska ”superbär” som utlovar att göra oss friska. Men vilka hälsoeffekter kan egentligen uppnås genom att äta bär? Är vissa bär mer nyttiga än andra? Forskningsresultaten som presenteras i denna avhandling visar att lingon, svarta vinbär och blåbär kan motverThe increasing prevalence of obesity is a worldwide health problem closely linked to diet and lifestyle factors. Obesity is associated with increased risk of several metabolic disorders including insulin resistance, nonalcoholic fatty liver disease and type 2 diabetes. Hence, there is a great need to identify dietary strategies for the prevention of obesity and related diseases. This thesis invest

Adsorption of Trimethyl Phosphate on Maghemite, Hematite, and Goethite Nanoparticles

Adsorption of trimethyl phosphate (TMP) on well-characterized hematite, maghemite and goethite nanopartides was studied by in situ DRIFT spectroscopy as a model system for adsorption of organophosphorous (OP) compounds on iron minerals. The iron minerals were characterized by X-ray diffraction (XRD), Raman spectroscopy, transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS)

Ethane thermometry using rotational coherent anti-Stokes Raman scattering (CARS)

The complete rotational CARS (coherent anti-Stokes Raman scattering) spectrum of ethane (C2H6) has for the first time been recorded instantaneously under high spectral resolution, and the potential for thermometry has been investigated. Experiments were performed in the temperature range 292-650K in pure ethane and in binary mixtures with nitrogen. A polarization technique was used to suppress the

Integration of particle-gas systems with stiff mutual drag interaction

Numerical simulation of numerous mm/cm-sized particles embedded in a gaseous disk has become an important tool in the study of planet formation and in understanding the dust distribution in observed protoplanetary disks. However, the mutual drag force between the gas and the particles can become so stiff - particularly because of small particles and/or strong local solid concentration - that an ex