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A pool of heparan sulphate-binding proteins (HSBPs) from Helicobacter pylori culture supernates was obtained by sequential ammonium sulphate precipitation and affinity chromatography on heparin-Sepharose, The chromatographic procedure yielded one major fraction that contained proteins with heparan sulphate affinity as revealed by inhibition studies of heparan sulphate binding to H. pylori cells. P
Idiopathic Scoliosis is a spinal deformity affecting approximately 3% of otherwise healthy children or adolescents. The etiology is still largely unknown but has an important genetic component. Genome-wide association studies (GWAS) have identified a number of common genetic variants that are significantly associated with idiopathic scoliosis in Asian and Caucasian populations, rs11190870 close to
In families screened for mutations in the BRCA1 or BRCA2 genes and found to have a segregating mutation the breast cancer risk for women shown not to carry the family-specific mutation might be at above "average" risk. We assessed the risk of breast cancer in a clinic based cohort of 725 female proven noncarriers in 239 BRCA1 and BRCA2 families compared with birth-matched controls from the Danish
Degradable starch microspheres (DSMs) are starch chains cross-linked with epichlorhydrin, forming glycerol-ether links. DSMs have been used for many years for temporary vascular occlusion and drug delivery in treatment of malignancies. They are also approved and used for topical haemostasis by absorbing excess fluid from the blood and concentrating endogenous coagulation factors, thereby facilitat
The Bone and Joint Decade 2000-2010 started as a Swedish initiative in 1996 leading to the UN declaration 1999 followed by the WHO launch 2000. A ten year multidisciplinary and global endeavor moving musculoskeletal conditions onto the research and health agenda is now recognized. Some lessons learned during the journey are presented.
The cortical representation of various body parts constantly changes based on the pattern of afferent nerve impulses. As peripheral nerve injury results in a cortical and subcortical reorganisation this has been suggested as one explanation for the poor clinical outcome seen after peripheral nerve repair in humans. Cutaneous anaesthesia of the forearm in healthy subjects and in patients with nerve
Multiconfiguration Hartree-Fock (MCHF) calculations of hyperfine constants for the 2s2p 3P states of beryllium and the ground states of boron and carbon are reported. The capacity of a recently developed configuration-interaction program [Froese Fischer and Tong (unpublished); Stathopoulos and Froese Fischer (unpublished)], allowing for large configuration expansions, is explored. Using a systemat
Close to 50 genetic loci have been associated with type 2 diabetes (T2D), but they explain only 15% of the heritability. In an attempt to identify additional T2D genes, we analyzed global gene expression in human islets from 63 donors. Using 48 genes located near T2D risk variants, we identified gene coexpression and protein-protein interaction networks that were strongly associated with islet ins
As breast volume may be associated with heart cancer risk, we studied the relationship between breast volume, CYP1A2*1F and coffee intake. Among healthy premenopausal non-hormone users, 3+ cups per day was associated with lower volume only in C-allele carriers (P(interaction)=0.02), which is consistent with reports that coffee protects only C-allele carriers against breast cancer.British Journal o
This article is later translated and published in English, partly as the same article, with the title: Ethics, parenthood and human rights: an evaluation of the reactions to the genetic revolution, Hocking, B. & Ryrstedt, E. 2004 Family life and Human Rights: papers presented at the 11th World Conference of the International Society of Family Law. Lødrup, P. & Modvar, E. (eds.). Gyldendal
A newly developed aluminium-polymer-laminated steel reflector for use in solar concentrators was evaluated with respect to its optical properties, durability, and reflector performance in solar thermal and photovoltaic systems. The optical properties of the reflector material were investigated using spectrophotometer and scatterometry. The durability of the reflector was tested in a climatic test
Lifetimes on the sub-nanosecond scale for the levels v(2)D(3/2), v(2)F(3/2) and v(2)F(5/2) in the 4d5s5p configuration in Zr II have been measured, using the method of laser-induced fluorescence. Combined with branching fractions obtained with the Lund Ultraviolet (UV) Fourier Transform Spectrometer (FTS), experimental oscillator strengths have been derived. From Hubble Space Telescope/Goddard Hig
This paper derives physical limitations on the interactions of antennas exciting TM or TE modes (but not both) and wireless propagation channels. The derivation is based on the spherical vector wave expansion of the electromagnetic field outside a sphere circumscribing the antennas. The result is an extension of the seminal work of Chu on the classical limitations on maximum antenna gain and radia
Background People applying for a housing adaptation (HA) grant are at great risk of participation restrictions due to declining capacity and environmental barriers. Aim To investigate the association of person-, environment-, and activity-related factors with participation frequency and satisfaction among people applying for a housing adaptation grant. Material and methods Baseline cross-sectional
Does a rising tide lift all boats? This question – that is, to what extent does improvements of the general economy benefit all – is central to the study of economics and history. From fundamental issues about whether market forces have an innate tendency to increase or decrease differences in economic outcomes, to much debated questions about the effects of government policies, distributional con
Popular Abstract in Swedish För att vi ska kunna lösa globala problem som miljöförstöring och fattigdom är det många som menar att den privata sektorn måste involveras på ett aktivt sätt. I den här avhandlingen, som består av en introduktion och fem vetenskapliga artiklar som tidigare publicerats i internationella tidskrifter, studeras ett exempel på hur privata aktörer faktiskt redan involverats It is commonly argued that the private sector needs to become actively involved for society to stand a chance of solving the most pressing global problems. This thesis, consisting of five articles previously published in refereed journals and an introductory essay, studies one case of private actor participation in global environmental governance: the Kyoto Protocol’s Clean Development Mechanism (
The main purpose of this study was to investigate whether the outcome obtained at the end of a work rehabilitation programme for people with various disabilities were stable in a one-year perspective. An additional aim was to explore which factors influenced the outcome upon completion of work rehabilitation and at the one-year follow-up. The study used information from a database and comprised 29
