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Methodology for developing reduced reaction mechanisms, and their use in combustion simulations

Combustion, present in a vast majority of energy and material production as well as in transportation, represents a foundation of our modern society. To improve and optimize the applications relying on combustion demand a high level of knowledge, and an ability to simulate the combustion process. To do so three-dimensional Computational Fluid Dynamic (CFD) combustion simulations can be used, where

Antibody-Fragments: Protein Engineering, Process Development, and their Application as Affinity Ligands

Monoclonal antibody (mAb) fragments have become the formats of choice for both biopharmaceuticals and ligands in analytical and preparative applications. Their smaller size enables additional advantages over full-length mAbs, such as improved tissue penetration, faster blood clearance for diagnostic applications, improved capacity, and enablement of multivalent formatting. However, limitations in

Precision Standard Model Phenomenology for High Energy Processes

The present status of particle physics is that the Standard Model has been completed with the discovery of theHiggs boson in 2012, but there is a multitude of phenomena in nature which is not accounted for by this model.Researchers are investigating possibilities for detecting new physics at the current particle physics facilities, withthe Large Hadron Collider (LHC) at the frontier. As no signifi

Embedding and Integrating a Digital Patient Management Platform Into Everyday Primary Care Routines: Qualitative Case Study

Background:Traditional primary care is characterized by patient consultations via phone and physical visits. However, the current development in Swedish primary care is to blend digital solutions with traditional solutions. This paper addresses this development by examining the normalization of embedding and integrating a digital health care platform into everyday care routines in a primary care c

Oxidation of Ketones: A (Chemo-) Enzymatic Approach Using Oxygenases and Hydrolases

Oxidation reactions are important in organic chemistry as well as in nature. In industry, oxidations are commonly used for the synthesis of chemicals and pharmaceuticals, however such processes have a number of limitations, they use chlorinated solvents, stoichiometric oxidation reagents, and in some cases the reagents that have risks of explosion during transportation and storage. This has called