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A urinary extracellular vesicle microRNA biomarker discovery pipeline; from automated extracellular vesicle enrichment by acoustic trapping to microRNA sequencing

Development of a robust automated platform for enrichment of extracellular vesicles from low sample volume that matches the needs for next-generation sequencing could remove major hurdles for genomic biomarker discovery. Here, we document a protocol for urinary EVs enrichment by utilizing an automated microfluidic system, termed acoustic trap, followed by next-generation sequencing of microRNAs (m

Global, regional, and national burden of neurological disorders during 1990-2015 : a systematic analysis for the Global Burden of Disease Study 2015

BACKGROUND: Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this syst

Tissue kallikrein: pathophysiological role in acute pancreatitis

Popular Abstract in Swedish Vävnadskallikrein (VK) är ett äggvitespjälkande protein som dels kan aktivera vävnadsnedbrytande enzymer som kollagenas och gelatinas och dels spjälkar kininogen till kininer (bradykinin och kallidin). Via bindning till speciella kininreceptorer (B2 receptorer) som finns överallt i kroppen, styr kininerna olika processer i de flesta av kroppens organ och vävnader såsom Tissue kallikrein releases pharmacollogically highly active kinins from kininogen. Many other enzymes may also release kinins. The aim of the study was to clarify the pathophysiological role of tissue kallikrein in acute pancreatitis. Two sensitive and specific radioimmunoassays for porcine and human tissue kallikrein were developed. A large release of tissue kallikrein from the pancreatic gland

Skåne idag och i framtiden

De beslut vi tar idag och i framtiden avgör om världen går mot en tvågraders- eller en fyragradersvärld, eller någonting där emellan. Vertikal samverkan mellan politiska nivåer och horisontell samverkan mellan sektorer är viktig för att möjliggöra kostnadseffektiva ambitiösa utsläppsminskningar och åtgärder för klimatanpassning i Skåne. Arbetet med Klimatsamverkan Skåne och Strukturbild för Skån

Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study

Background Trials of imatinib have provided evidence of activity in adults with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (ALL), but the drug's role when given with multidrug chemotherapy to children is unknown. This study assesses the safety and efficacy of oral imatinib in association with a Berlin-Frankfurt-Munster intensive chemotherapy regimen and allo geneic stem-cell tr

Outcome of patients with acquired aplastic anemia given first line bone marrow transplantation or immunosuppressive treatment in the last decade: a report from the European Group for Blood and Marrow Transplantation (EBMT)

BACKGROUND AND OBJECTIVES: The treatment of acquired aplastic anemia (AA) is based on allogeneic bone marrow transplantation (BMT) and immunosuppressive therapy. The aim of this study was to assess the outcome of children and adults with AA treated in the last decade, and to determine whether results have improved in two sequential time periods,1991-1996 and 1997-2002. DESIGN AND METHODS: Two-thou

Total Quality Indicators for the Food Production Chain: is there a need for more labelling?

The state of the farming industry in Europe has been put under the spotlight in recent years due to a number of different food scares and disease outbreaks. Many new quality assurance schemes have been formed to accompany the existing environmental monitoring schemes, to give concerned consumers some guarantee when buying food that it is of a good quality and the environmental load of production h

Att behandla alla lika fast alla är olika. En studie om det sociala arbetet med barnfamiljer med annan språkbakgrund

The aim of this study was to investigate the social worker's role and vision in the work with children and families who have a different language background. Social workers with families with several languages have expanded in Sweden in recent years, and that's why I think it is an interesting subject to study. I study about what room for maneuver they have in the meeting with the families

Att behandla alla lika fast alla är olika. En studie om det sociala arbetet med barnfamiljer med annan språkbakgrund

The aim of this study was to investigate the social worker's role and vision in the work with children and families who have a different language background. Social workers with families with several languages have expanded in Sweden in recent years, and that's why I think it is an interesting subject to study. I study about what room for maneuver they have in the meeting with the families

Childhood Habituation in Evolution of Augmenting Topologies (CHEAT)

Artificiella Neuronnät är datorvärldens ekvivalens till det mänskliga nervsystemet. Precis som nervsystemet är ett nätverk av neuroner som är kopplade till andra neuroner med nerver så är det artificiella neuronnätet ett näverk av noder som är kopplade till andra noder med länkar. Det artificiella neuronnätet tar en inputsignal som skickas igenom nätverket och där noderna signalen stöter på på vägNeuroevolution is a field within machine learning that applies genetic algorithms to train artificial neural networks. Neuroevolution of Augmenting Topologies (NEAT) is a method that evolves both the topology of the network and trains the weights of the network at the same time, and has been found to successfully solve reinforcement learning problems efficiently and the XOR problem with a minimal

Pollen analytical and landscape reconstruction study at Lake Storsjön, southern Sweden, over the last 2000 years

This thesis reports the results from a pollen analytical and quantitative landscape reconstruction (REVEALS model) study in the drainage area of the Botorpsströmmen River in southern Sweden as a part of the project The archaeology and ecology of collapse: social and agricultural change following the Black Death and the project Managing Multiple Stressors in the Baltic Sea. The focus of this study

Pharmacometabolomic Profiling Of The General Population: Relation Of Active Metabolite Levels To Cardiovascular Risk Factor Control And Manifest Atherosclerosis

Introduction: The use of medications in the general population has increased over time. Information on active metabolite concentrations for common drugs in the general population is limited. Recent advances in metabolomic technologies have made high-throughput profiling of many active metabolites in large epidemiological cohorts increasingly feasible.Aim: 1. Prospective assessment of the proportio

Protokoll kfs 240619-signed (1)

Sida 1 av 3 Fakultetsstyrelsen PROTOKOLL Diarienummer STYR 2024/1711 Sammanträdesdatum 2024-06-19 Konstnärliga fakultetsstyrelsens sammanträde 2024-06-19 Ledamöter Närvarande Staffan Storm, prodekan, mötesordförande Santino Resić, dekan – via Zoom Håkan Andersson, universitetslektor Musikhögskolan Sven Bjerstedt, docent Teaterhögskolan, justerare Mats Edén, universitetslektor Musikhögskolan Maria

https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/2024-06/protokoll_kfs_240619-signed%20(1).pdf - 2026-05-29

Karkee krishna

1 Effects of Deforestation on Tree Diversity and Livelihoods of Local Community: A Case Study from Nepal By Krishna Karkee PO Box: 170 222 00 Lund, Sweden krishna.karkee.142@student.lu.se A thesis submitted to the Lund University International Master’s Programme in Environmental Science (LUMES) in partial fulfillment of the requirements for the degree of Master of Environmental Science Advisor Pro

https://www.lumes.lu.se/sites/lumes.lu.se/files/karkee_krishna.pdf - 2026-05-29