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The separator is a machine with many applications, commonly used to separate liquids or solids into components with different density. Each application demands its own unique set of process parameters to achieve optimal results. Often the procedure of finding the best process parameters is conducted empirically, which can be very time consuming. This thesis aims to address this problem by providin

7 miljoner människor dör varje år på grund av cigarrettrökning. Idag finns det flera olika produkter på marknaden som kan hjälpa personer att sluta denna dåliga vana. Den första var Nicorette® tuggummin. När McNeil AB producerar Nicorette® tuggummin, följer McNeil de strikta kraven på kvalité som de regulatoriska myndigheterna kräver. Dessa krav tvingar McNeil att slänga tonvis av tuggummin varje McNeil AB produces pharmaceutical chewing gums that contains nicotine. Since this smoking cessation product is a pharmaceutical, the regulatory agencies demand that any gums outside pre-set specifications are discarded. Some batches have more discarded material than others, due to the variability in the manufacturing process. By analysing this variability, the personnel could make choices that low

Cancer of unknown primary (CUP) is a heterogeneous syndrome diagnosed at metastatic sites. The etiology is unknown but immune dysfunction may be a contributing factor. Patients with autoimmune diseases were identified from the Swedish Hospital Discharge Register and linked to the Swedish Cancer Registry. Standardized incidence ratios (SIRs) were calculated for subsequent CUP and compared with subj

Presented at the Europan Inter-Sessions Forum (2021), an international platform bringing together winning teams, municipalities, and researchers to discuss the transition from competition ideas to implementation processes, this contribution focuses on Lerum E10, a collaborative project by Marco Pusterla and Jesús Mateo, developed within Europan 10, a European competition and research platform for

Epidemiological studies indicate that risks of certain cancers are increased in individuals hospitalized for type 2 diabetes mellitus (T2DM), which may not be representative of the entire population of T2DM patients as most of them are treated in primary health cares. To examine the subsequent cancer risk in individuals with T2DM from hospitals and primary health cares, and in their siblings and s

TURBT is the initial diagnostic procedure in bladder cancer (BC). Hypothetically, tumor resection could induce seeding of cancer cells into the circulation and subsequent metastatic disease. The objective of this study was to ascertain whether TURBT induces measurable seeding of cancer cells into the vascular system.

It has been suggested that alcohol consumption is associated with increased risk of a few solid cancers, although studies that examined the association with hematological malignancies have shown inconsistent results. In this study, we examined the risk of hematological malignancies among individuals who had alcohol use disorders (AUDs) in Sweden.

Previous studies suggest that hormone therapy may play an important role in the development of meningioma. However, it is unclear whether medication with tamoxifen can prevent meningioma. Our study cohort included all women who were diagnosed with breast cancer between 1961 and 2010, and a total of 227 535 women were identified with breast cancer with a median age at diagnosis of 63 years. Women d

The association between breast cancer and warfarin is inconclusive as most previous studies examined their association using patients with thromboembolism, whereas thromboembolism itself is a risk factor for cancer. We explored this issue using patients received mechanical heart valves replacement as a proxy for warfarin exposure as these patients need a lifelong warfarin treatment, and compared t

Background:Individuals with lactose intolerance are recommended to avoid milk or dairy products, which may affect the development of cancer.Methods:We identified individuals with lactose intolerance from several Swedish Registers linked to the Swedish Cancer Registry to calculate standardised incidence ratios (SIRs) for cancers in the breast, lung, and ovary.Results:A total of 22 788 individuals w

Background. Previous studies found an increased risk of cancer in hospitalized asthma patients, but it is not known whether patients from primary health care show a similar risk pattern. In addition, it is unclear whether the diagnosis of asthma can influence the prognosis of subsequent cancer. Methods. Asthma patients were identified from Swedish inpatient, outpatient, and primary health care reg

Cancer runs in families, suggesting a heritable component, but the contribution of environmental factors cannot be neglected. Studies on spousal risk can partly disentangle the environmental contribution but miss shared environmental factors during childhood and adolescence. Here, we examined the familial aggregation of common cancers among 80 281 Swedish-born adoptees, identified from the nationa

Abstract in Undetermined Comment: Geoengineering efforts to bring oxygen into the deep Baltic should be abandoned, says Daniel J. Conley

The cumulative risk of NHL in Sweden by age 80 years has increased to 1.1 in women and 1.6% in men in 2011. Increased risk of non-Hodgkin lymphoma (NHL) associated with personal histories of some autoimmune diseases (ADs) are known. It is unclear whether there are other NHL-related ADs and whether this association holds across different sex, age and year of diagnosis, or NHL histological subtypes.

Background & Aims Cholera toxin can act as a modulator of the immune response with anti-inflammatory effects; it reduces development of colon polyps in mouse models of colorectal cancer (CRC). We performed a population-based study to determine whether, in patients with a diagnosis of CRC, subsequent administration of the cholera vaccine (killed Vibrio cholerae O1 whole cells and recombinant ch

To understand the developmental trajectories in early lymphocyte differentiation, we identified differentially expressed surface markers on lineage-negative lymphoid progenitors (LPs). Single-cell polymerase chain reaction experiments allowed us to link surface marker expression to that of lineage-associated transcription factors (TFs) and identify GFRA2 and BST1 as markers of early B cells. Funct