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Synthesis, solvent-, and guest-controlled self-assembly, and self-sorting of new hydrogen-bonded chiral cavity receptors are reported. The design of the cavity is based on the cyclic self-aggregation of monomers containing the 4H-bonding ureidopyrimidinone motif fused with the bicylo[3.3.1]nonane framework. Selective formation of kinetically inert cyclic tetramers is observed in chloroform, while

The ability to make specific perturbations to biological molecules in a cell or organism is a central experimental strategy in modern research biology. We have developed a general technique in which the stability of a specific protein is regulated by a cell-permeable small molecule. Mutants of the Escherichia coil dihydrofolate reductase (ecDHFR) were engineered to be degraded, and, when this dest

Photoinduced bimolecular charge transfer processes involving the iron(III) N-heterocyclic carbene (FeNHC) photosensitizer [Fe(phtmeimb)2]+ (phtmeimb = phenyltris(3-methyl-imidazolin-2-ylidene)borate) and triethylamine as well as N,N-dimethylaniline donors have been studied using optical spectroscopy. The full photocycle of charge separation and recombination down to ultrashort time scales was stud

Background: The aim was to identify and characterize rare malignancies of the gallbladder, incidentally found at cholecystectomy, and describe the diagnostic work-up, treatment and outcome. Methods: Data from cholecystectomies during 2007–2014 registered in the Swedish Register for Gallstone Surgery (GallRiks) were analyzed for incidental cancer. For completion of the pathology report, data were l

Background: Incidental gallbladder cancer is a rare event, and its prognosis is largely affected by the tumour stage and treatment. The aim of this study was to analyse the management, treatment and survival of patients with incidental gallbladder cancer in a national cohort over a decade. Methods: Patients were identified through the Swedish Registry of Gallstone Surgery (GallRiks). Data were cro

Objective: Children of mothers with severe mental illness are at significantly increased risk of developing intellectual disability. Obstetric complications are also implicated in the risk for intellectual disability. Moreover, children of mothers with severe mental illness are more likely to be exposed to obstetric complications. The purpose of this study was to examine the independent and joint

Although significant improvements have been achieved for organic photovoltaic cells (OPVs), the top-performing devices still show power conversion efficiencies far behind those of commercialized solar cells. One of the main reasons is the large driving force required for separating electron-hole pairs. Here, we demonstrate an efficiency of 14.7% in the single-junction OPV by using a new polymer do

Background: Presence of circulating tumor cells (CTCs) is a validated prognostic marker in metastatic breast cancer. Additional prognostic information may be obtained by morphologic characterization of CTCs. We explored whether apoptotic CTCs, CTC clusters and leukocytes attached to CTCs are associated with breast cancer subtype and prognosis at base-line (BL) and in follow-up (FU) blood samples i

This paper presents an implementation for a baseband massive multiple-input multiple-output (MIMO) application-specific instruction set processor (ASIP). The ASIP is geared with vector processing capabilities in the form of single instruction multiple data (SIMD), and furthermore exploits instruction level parallelism by employing a very large instruction word (VLIW) architecture. Additionally, a

Today, the advances in airborne LIDAR technology provide high-resolution datasets that allow specialists to detect archaeological features hidden under wooded areas more efficiently. Still, the complexity and large scale of these datasets require automated analysis. In this respect, artificial intelligence (AI)-based analysis has recently created an alternative approach for interpreting remote sen

BACKGROUND: The major risk factors for atherosclerotic cardiovascular disease differ by race or ethnicity but have largely been defined using populations of European ancestry. Despite the rising prevalence of cardiovascular disease in Africa there are few related data from African populations. Therefore, we compared the association of established cardiovascular risk factors with carotid-intima med

This paper presents the design and comparison of an active Gm-C and a passive baseband filter for 6G applications. Both presented circuits are 5th-order differential low-pass filters with 3-dB cut-off frequencies of 4.9 and 4.7 GHz, respectively, implemented in a 22 nm FD-SOI CMOS technology. The active filter uses back-gate tuning to optimize the transfer function, and achieves a measured in-band

Gaze-control and gaze-assistance in software development tools have so far been explored in the setting of code editing, but other developer activities like code review could also benefit from this kind of tool support.In this paper, we present GANDER, a platform for user studies on gaze-assisted code review. As a proof of concept, we extend the platform with an assistant that highlights name rela

We present a detailed investigation into a source of distortion that affects the classic bootstrapped switch. Our analysis reveals that the transition phase between track mode and hold mode is a critical factor in causing the distortion. To address this issue, we propose a novel technique that effectively mitigates the problem. Our results, based on simulations conducted using a 22-nm FDSOI CMOS p

Objective: Obstetric anal sphincter injuries (OASIS) are severe complications to vaginal births with potential long-term consequences. Maternal origin has been proposed to affect the overall risk, but the association and underlying explanation are uncertain. The objective was to assess the association between maternal country of birth and OASIS. Methods: A Swedish nationwide cohort study including

Distributed multiple-input multiple-output (D-MIMO) is a promising technology for simultaneous communication and positioning. However, phase synchronization between multiple access points in D-MIMO is challenging and methods that function without the need for phase synchronization are highly desired. Therefore, we present a method for D-MIMO that performs direct positioning of a moving device base