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IMPORTANCE: Breast cancer (BC) is the second leading cause of cancer death in women, and there is a substantial disparity in BC mortality by race, especially for early-onset BC in Black women. Many guidelines recommend starting BC screening from age 50 years; however, the current one-size-fits-all policy to start screening all women from a certain age may not be fair, equitable, or optimal.OBJECTI

AIM: To study the association between within-person changes in patient-reported outcomes (PROMs) and wish for joint surgery during participation in a digital first-line intervention comprising exercise and education for knee/hip osteoarthritis (OA).METHODS: Retrospective observational registry study. Participants enrolled between 01/06/2018 and 30/10/2021 with follow-up data at 3 months (n=13,961)

Background and Purpose: Target delineation in glioblastoma is still a matter of extensive research and debate. This guideline aims to update the existing joint European consensus on delineation of the clinical target volume (CTV) in adult glioblastoma patients. Material and Methods: The ESTRO Guidelines Committee identified 14 European experts in close interaction with the ESTRO clinical committee

When most of us think of solar technology, we picture photovoltaic panels on sunny rooftops capturing clean energy for self-sufficient households. This vision suggests that increasing the installation of solar panels will reduce greenhouse gas emissions and encourage more democratic energy pathways. But the way solar technology relates to global environmental and social problems is actually very d

hange detection is an important application in remote sensing earth observation which leads to identification of significant environmental events, forest and agricultural landmonitoring. In this paper, we introduce a standalone softwarefor two well-known change detection methods, omnibus test and iteratively re-weighted multivariate alteration detection (IR-MAD). Omnibus test deals with synthetic

The NA62 experiment at CERN reports searches for K+→μ+N and K+→μ+νX decays, where N and X are massive invisible particles, using the 2016–2018 data set. The N particle is assumed to be a heavy neutral lepton, and the results are expressed as upper limits of O(10−8) of the neutrino mixing parameter |Uμ4|2 for N masses in the range 200–384 MeV/c2 and lifetime exceeding 50 ns. The X particle is consi

An experiment has been performed to study excited states in the neutron-deficient nucleus Ir175 via the use of the JUROGAM II high-purity germanium detector array and the RITU gas-filled separator at JYFL, Jyväskylä. By using isomer tagging, an isomeric state with a half-life of 6.58(15) μs has been observed in Ir175 for the first time. It has been established that the isomer decays via a 45.2 (E1

A search for the Zγ decay of the Higgs boson, with Z boson decays into pairs of electrons or muons is presented. The analysis uses proton–proton collision data at s = 13 TeV corresponding to an integrated luminosity of 139 fb−1 recorded by the ATLAS detector at the Large Hadron Collider. The observed data are consistent with the expected background with a p-value of 1.3%. An upper limit at 95% con

PoxtA and OptrA are ATP binding cassette (ABC) proteins of the F subtype (ABCF). They confer resistance to oxazolidinone and phenicol antibiotics, such as linezolid and chloramphenicol, which stall translating ribosomes when certain amino acids are present at a defined position in the nascent polypeptide chain. These proteins are often encoded on mobile genetic elements, facilitating their rapid s

This paper documents the development of a sustainable greenhouse system which incorporates a greenhouse, reverse electrodialysis (RED), reverse osmosis, and a dehumidification desalination system aiming to support water and energy self-sufficient agriculture in arid regions with a saline groundwater feed. The system is referred to as the sustainable greenhouse (SGH). The aim is to generate enough

The stability of relaxation techniques has been studied for strongly coupled fluid-structure interaction (FSI) with application to a cantilever immersed in channel flow. The fluid is governed by Navier–Stokes equations for incompressible flow condition using turbulence modeling, and the solid is governed by the equation of motion with compressible material modeling. The applied kinematic descripti

Mitigating climate change will require large-scale changes to energy systems. Two examples are increased use of renewable energy resources and electrification of the transport sector. These changes increase demand for metals. This chapter looks into which metals are used in renewable energy technologies and why, how much is required to transition the global energy system and which countries hold t

All over the world there is a shortage of adequate, affordable housing that enables social integration and sustainability. Many individuals and households have access to housing but live in different kinds of involuntary isolation with respect to age, gender, income, culture and ethnic background. There is a lack of housing forms that can contribute to solving these societal challenges through dif

An analytical method is developed for ultrasensitive detection of citrinin using double isothermal amplification and CRISPR-Cas12a. Gold nanoparticles (AuNPs) modified with antigen and thiol-terminated, single-strand DNA (ssDNA) are used as a probe. The antigen-modified AuNPs compete with citrinin to bind to magnetic beads coated with an anticitrinin antibody. After a simple magnetic separation, t

Understanding the inherited nature of how biological processes dynamically change over time and exhibit intra- and inter-individual variability, due to the different responses to environmental stimuli and when interacting with other processes, has been a major focus of systems biology. The rise of single-cell fluorescent microscopy has enabled the study of those phenomena. The analysis of single-c