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We report on a large scale calculation concerning the 5s(2) S-1 and 5s5p P-1,P-3 levels in Sr-88 I, using multiconfiguration Dirac-Fock methods. Our focus is on the P-3(2) meta-stable level, which has been shown to be extremely useful in atom cooling and trapping experiments. The lifetime for this level from our work (1071 s) agrees very well with a previous theoretical value, but not with the ava

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Gaussian wave models have been successfully used since the early 1950s to describe the development of random sea waves, particularly as input to dynamic simulation of the safety of ships and offshore structures. A drawback of the Gaussian model is that it produces stochastically symmetric waves, which is an unrealistic feature and can lead to unconservative safety estimates. The Gaussian model des

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We present an algorithm for the computation of the stress field around a branched crack. The algorithm is based on an integral equation with good numerical properties. Our equation is obtained through a left regularization of an integral equation of Fredholm's first kind. Complex valued functions involving repeated products of square roots appear in the regularization. A new and effective scheme f

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The hallmark of severe haemophilia, defined as a circulating level of factor (F) VIII (haemophilia A cases) or FIX (haemophilia B cases) of < 1%, is recurrent bleeding into muscles and joints (haemarthroses) from an early age of life. The inevitable result of such bleeding is progressive joint damage, leading to disabling arthritis that is typically evident within the first 2 decades of life in pe

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The interactions between wild-type or mutant recombinant forms of human cystatin C and rat cathepsin B were characterized by measuring progress curves for substrate hydrolysis in the presence of inhibitor. The investigation was guided by the use of computer modeling and explores the possibility that amino acid residues in the N-terminal region of cystatin C interact with substrate-binding regions

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We present a method for parametrizing the Zeeman effect in hydrogen-like systems in high-temperature plasmas, where the fine-structure is completely unresolved. The method is based on the observation that the different polarization components behave collectively like separate entities, with simple relations. The entire Zeeman pattern can then be reduced to just three components, whose dependence o

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The present multidisciplinary study examined nigrostriatal dopamine and striatal amino acid transmission in the R6/1 line of transgenic Huntington's disease (HD) mice expressing exon 1 of the HD gene with 115 CAG repeats. Although the number of tyrosine hydroxylase-positive neurons was not reduced and nigrostriatal connectivity remained intact in 16-week-old R6/1 mice, the size of tyrosine hydroxy

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The brackish water cyanobacterium Nodularia spumigena produce the hepatotoxic cyclic pentapeptide nodularin. Intoxications for both human as well as animal may arise when water reservoirs are contaminated with potentially toxic Nodularia species. Here, results of three independent methods for the determination of nodularin in different strains of N. spumigena are presented. The results obtained wi

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OBJECTIVE: Critical limb ischemia (CLI) is a peripheral arterial disease manifested by drastically diminished blood flow to the legs, pain at rest, nonhealing wounds, and gangrene caused by atherosclerosis. Significant tissue necrosis is associated with late stage CLI and the patients have a poor prognosis. Necrotic and apoptotic cells activate complement and bind complement inhibitor C4b-binding

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Consider a parametrized family of general hidden Markov models, where both the observed and unobserved components take values in a complete separable metric space. We prove that the maximum likelihood estimator (MLE) of the parameter is strongly consistent under a rather minimal set of assumptions. As special cases of our main result, we obtain consistency in a large class of nonlinear state space

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A resultant-type identity for univariate polynomials is proved and used to characterise SAGBI bases of subalgebras generated by two polynomials. A new equivalent condition, expressed in terms of the degree of a field extension, for a pair of univariate polynomials to form a SAGBI basis is derived.

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Background: The 39 item Parkinson's disease questionnaire (PDQ-39) is the most widely used patient reported rating scale in Parkinson's disease. However, several fundamental measurement assumptions necessary for confident use and interpretation of the eight PDQ-39 scales have not been fully addressed. Methods: Postal survey PDQ-39 data from 202 people with Parkinson's disease (54% men; mean age 70

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The potential of algal–bacterial microcosms was studied for the biodegradation of salicylate, phenol and phenanthrene. The isolation and characterization of aerobic bacterial strains capable of mineralizing each pollutant were first conducted. Ralstonia basilensis was isolated for salicylate degradation, Acinetobacter haemolyticus for phenol and Pseudomonas migulae and Sphingomonas yanoikuyae for

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A simple model is presented which interpolates between the DGLAP and BFKL regimes in deep inelastic cp scattering. This model is based on the CCFM and LDC models, and it is simple enough to provide an intuitive picture of the transition region between the two domains. Results are presented for both fixed and running coupling; for fixed coupling the transition between the domains occurs at a consta

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A compact six-figure approximation formula for the inductance of a cylindrical current sheet is presented. The formula displays the correct asymptotic behavior in the respective cases of very long and very short coils. The efficiency of the approximation formula is due to a thorough analysis of the exact formula.

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There is a need for mathematical modelling for the evaluation of important parameters for photon imaging systems. A Monte Carlo program which simulates medical imaging nuclear detectors has been developed. Different materials can be chosen for the detector, a cover and a phantom. Cylindrical, spherical, rectangular and more complex phantom and source shapes can be simulated. Photoelectric, incoher