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Malignant melanoma is a very aggressive skin cancer, characterized by a heterogeneous nature and high metastatic potential. The incidence of melanoma is continuously increasing worldwide, and it is one of the most common cancers in young adults. In the past twenty years, our understanding of melanoma biology has increased profoundly, and disease management for patients with disseminated disease ha

BACKGROUND: There are important unmet clinical needs to develop cell enrichment technologies to enable unbiased label-free isolation of both single cell and clusters of circulating tumor cells (CTCs) manifesting heterogeneous lineage specificity. Here, we report a pilot study based on microfluidic acoustophoresis enrichment of CTCs using the CellSearch CTC assay as a reference modality.METHODS: Ac

Objective: To evaluate the precision of the predictive cost-effectiveness assessment based on a phase 3 clinical trial with infliximab for the treatment of rheumatoid arthritis in Swedish clinical practice. Methods: Three patient cohorts were identified: the patients included in the infliximab trial (ATTRACT), patients initially treated with infliximab from a Swedish registry (STURE), a subset of

By studying the continuity between the Ottoman Empire and its succeeding Turkish Republic, this article aims to address one crucial aspect of the denial of the Armenian genocide by the Turkish state, namely the issue of state responsibility. There are psychological barriers in Turkey which have largely suppressed the memories of possible wrongdoings during World War I and the ensuing ‘Independence

Ageing significantly alters the body in different ways, especially our perception and experience of it. In the phenomenological perspective, the human mind and body are intertwined with each other as well as intertwined with the surrounding world; consequently an altered body will affect the experience of both self and the world. This article discuss how and when ageing and old age affect the expe

Ocean evaporation, represented by latent heat flux (LE), plays a crucial role in global precipitation patterns, water cycle dynamics, and energy exchange processes. However, existing bulk methods for quantifying ocean evaporation are associated with considerable uncertainties. The maximum entropy production (MEP) theory provides a novel framework for estimating surface heat fluxes, but its applica

This A-Z Guide offers an accessible and user-friendly overview of the essential concepts and terms needed to understand the implementation of the SDGs. Crafted in the form of an encyclopaedia, the volume presents 105 entries on important concepts and terms and their links to academic and policy debates. Each entry offers basic definitions of the concept or term at issue, followed by a brief discus

To explore the extent to which client characteristics, decision-maker attributes, and country influence judgments of institutional long-term care (ILTC) appropriateness for people with dementia. Design, setting, and participants: A total of 161 experts in dementia care from 8 European countries reviewed a series of 14 vignettes representing people with dementia on the cusp of ILTC admission and in

Our existing urban environment has a significant potential to increase the use of renewable energy, mainly by using solar irradiation for heat and electricity. Quantification of the solar potential by means of a solar map is the first step in the acceleration process for using more solar energy in our urban environments. A solar map is a GIS system providing the annual solar irradiation on buildin

In the EC project, ANNIE (Application of Neural Networks to Integrated Ergonomics) the aim is to develop a human simulation and ergonomic evaluation tool based on a neural network. Recorded movement patterns from subjects, performing tasks in real environments, will train the network. The net will control a mannequin, to perform human-like movements. The human model will be placed in different vir

Manuskriptideer Kursvärdering 2013: GEOA73; Dinosauriernas värld (lärare: Johan Lindgren, Mats Eriksson, Per Ahlberg, Johan Gren, Sven Stridsberg, Vivi Vajda) SAMMANSTÄLLNING BASERAD PÅ 32 SVAR 1. Hur upplevde Du kursen i allmänhet (från 1-5 där 1 är usel och 5 är toppen)? Markera med kryss. (1) (2) (3) 3% (4) 47% (5) 50% 2. Hur upplevde Du föreläsningarna (från 1-5 där 1 är usel och 5 är toppen)?

https://www.geologi.lu.se/sites/geologi.lu.se/files/geoa73-kursvardering.pdf - 2026-06-27

Kalendarium | HT-biblioteken Kalendarium Rss-flöde Händelsetyp Alla händelser Workshop Händelser per termin Välj termin vårterminen 2025 höstterminen 2025 vårterminen 2026 höstterminen 2026 vårterminen 2027 3 sep 3 september 2026 15:00 till 16:00 Workshop Kom med din text! (drop-in) 10 sep 10 september 2026 15:00 till 16:00 Workshop Kom med din text! (drop-in) 17 sep 17 september 2026 15:00 till 1

https://www.htbibl.lu.se/om-oss/kalendarium/ - 2026-06-27

Environmental factors in the development of Type 1 diabetes Hui Peng & William Hagopian Published online: 4 January 2007 # Springer Science + Business Media, LLC 2007 Abstract Environmental factors appear to play an important role in the pathogenesis of childhood-onset type 1 diabetes (T1D). The most important factors are thought to be infectious, dietary, perinatal, and psychosocial. Enterovi- ru

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_02_peng_remd_2006.pdf - 2026-06-27

untitled Factors associated with longitudinal food record compliance in a paediatric cohort study Jimin Yang1,*, Kristian F Lynch1, Ulla M Uusitalo1, Kristina Foterek2, Sandra Hummel3, Katherine Silvis4, Carin Andrén Aronsson5, Anne Riikonen6, Marian Rewers7, Jin-Xiong She4, Anette G Ziegler3, Olli G Simell8, Jorma Toppari9, William A Hagopian10, Åke Lernmark5, Beena Akolkar11, Jeffrey P Krischer1

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_47_yang_phn_2015.pdf - 2026-06-27

Human dUTPase, expressed in Escherichia coli, has been crystallized. Single crystals were obtained by the vapour-diffusion technique using 2-propanol and PEG 4000 as precipitants. The enzyme was co-crystallized with the substrate dUTP and a metal chelator EDTA to prevent hydrolysis of the substrate. The crystals belong to the orthorombic space group P212121 with cell dimensions a = 67.51, b = 68.2

Serum samples from patients referred for liver biopsy for investigation of suspected chronic liver disease (n = 286) and from healthy middle-aged volunteers (n = 445) were analyzed for markers of exposure to GB virus C/hepatitis G virus (GBV-C/HGV), hepatitis B virus and hepatitis C virus. GBV-C/HGV analyses included GBV-C/HGV PCR for detection of viremia and GBV-C/HGV enzyme-linked immunosorbent