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Sprifermin, recombinant human fibroblast growth factor 18 (rhFGF18), induces cartilage regeneration in knees of patients with osteoarthritis (OA). We hypothesized that a temporal multiphasic process of extracellular matrix (ECM) degradation and formation underlie this effect. We aimed to characterize the temporal ECM remodeling of human knee OA articular cartilage in response to sprifermin treatme
A protective coating is often used on the cladding of wooden facades to limit the absorption of moisture. Low wood moisture content (MC) is essential to obtain satisfactory durability performance. Wood density is known to influence the water sorption and crack formation of uncoated wood. However, the effect of density on the aforementioned behaviors of coated spruce is not yet fully understood. Si
PURPOSE: To evaluate the effect of radiation dose reduction on image ++quality in computed musculoskeletal radiography and determine optimal exposure range. MATERIAL AND METHODS: In 11 corpses, 1 hand and 1 hip were examined with film-screen radiography, and a series of computed radiographs was obtained using exactly the same technique except for the exposure, which was 100, 50, 25, 12.5, 6.25, an
Ever since the dawn of internet, a new wave of fast-growing software companies has emerged. The M&A scholars have struggled to find appropriate valuation mechanisms for unprofitable companies with ultra-high revenue growth. To overcome the uncertain future, a contractual provision called earnout is often used. An earnout is a contractual provision in a M&A-deal that states the seller of th
In Statistical Shape Modeling, a dense correspondence between the shapes in the training set must be established. Traditionally this has been done by hand, a process that commonly requires a lot of work and is difficult, especially in 3D. In recent years there has been a lot of work on automatic construction of Shape Models. In recent papers (Davies et al., Medical Image Computing and Computer-Ass
A highly optimized Monte Carlo (MC) code package for simulating light transport is developed on the latest graphics processing unit (GPU) built for general-purpose computing from NVIDIA - the Fermi GPU. In biomedical optics, the MC method is the gold standard approach for simulating light transport in biological tissue, both due to its accuracy and its flexibility in modelling realistic, heterogen
I år var andra gången som Lunds universitet genomförde en universitetsgemensam pedagogisk utvecklingskonferens, första gången var 2007. Konferensen, som är ett samarrangemang mellan samtliga fakulteter och CED, har nu alltså blivit en återkommande aktivitet! Samhällsvetenskapliga fakulteten stod värd för årets konferens och dekanus Ann-Katrin Bäcklund sträckte vid invigningen fram en symbolisk sta
Vitreoscilla is an obligate aerobic bacterium found in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla induces the production of a homodimeric hemoglobin (VHb) when subjected to oxygen-limiting conditions. It is thought that VHb facilitates oxygen delivery to the respiratory apparatus of its host by increasing the local oxygen concentration under oxygen-
Besökarna kring Ivösjön har på senare år märkt av en förändring av vegetationen kring och i Ivösjön och därigenom en förändring av strandlinjens utformning. Sjön tycks allt mer växa igen av vass och flytbladsväxter, vilket tyder på en eutrofieringsprocess. I den här rapporten jämförs flygbilder från olika tidpunkter under en 70-års period fram till och med idag för att se om sjön verkligen har vuxThe visitors around Ivösjön have recently discovered observed a change in the vegetation around and into the lake and consequently a change in the formation of the shoreline. The lake appears to have been increasingly filled up by reed and floating leaf plants which points to an eutrophication process. In this report aerial photographs are compared from a period of 70 years up until today to disco
En vårdnadstvist hör ofta samman med föräldrars separation, vilken kan grunda sig i en konflikt föräldrarna emellan. Domstolens prövning kan även komma att påverka barnet i olika hänseenden. Det händer att en förälder hävdar att det finns en risk för barnet att vara med den andra föräldern. Det kan vara en anklagelse om att den andra föräldern allvarligt har misshandlat barnet eller föräldern, misChild custody cases brought before a civil court often consist of a conflict between two parents. A child custody dispute may also affect the child in several aspects. A parent may claim there is a risk to the child when spending time with the other parent. Such an allegation may consist of child abuse, domestic violence, substance abuse, child abduction or mental ill health. The enumerated circum
Sammanfattning Skatteverket kan företa revisioner hos i huvudsak bokföringsskyldiga skattskyldiga, i regel näringsidkare, för att granska riktigheten av de uppgifter som lämnats till Skatteverket i deklarationer och kontrolluppgifter. Vid dessa revisioner granskas den skattskyldiges bokföring och andra underlag för att stämmas av mot de uppgifter som lämnats till Skatteverket. Skatteverket kan äSummary The Swedish Tax Agency is authorized to carry out audits, mainly with accountable taxable’s, normally corporations, in order to scrutinize the accuracy of the information that has been submitted to the Swedish Tax Agency through income tax returns and statements of earnings. In such audits the taxable’s accounting and other materials are compared against the information that has been submi
This scientific report has mainly studied the concept of Industry 4.0 and the possibility to send data from a temperature sensor to the cloud, a process which is an example of the term Internet of Things. The study has been conducted for the consultant business Rejlers to give the CEO as well as the Technical Manager a broader view of how they could implement IoT on behalf of costumers in the futu
With countries across the world finding pathways to counter CO2 emissions, sustainable mobility has become a critical topic for leaders, policymakers, and industries. The development of Battery Electric Vehicles (BEV’s) is seen as an important and effective way through which reliance on fossil fuels and thereby related CO2 emissions can be reduced. Statistics show that the number EV’s on the roads
With countries across the world finding pathways to counter CO2 emissions, sustainable mobility has become a critical topic for leaders, policymakers, and industries. The development of Battery Electric Vehicles (BEV’s) is seen as an important and effective way through which reliance on fossil fuels and thereby related CO2 emissions can be reduced. Statistics show that the number EV’s on the roads
This report explains my degree project at Lund University School of Industrial Design. The project started out by exploring the materials Wood and Textile, although after researching the two areas further it seemed more valuable to look into the way we consume these materials today. We do not have unlimited natural resources, and yet we keep using them as if we do. I chose to reduce the project in
The purpose of this work has been to perform numerical calculations on the cubical mixing tank the QB mixer, to be able to verify its strength and try to improve it. The QB mixer is produced by the company QB FoodTech AB. Firstly a CAD model was made from drawings of the mixer. Then the structure was analysed in aspects of pressure load, thermal loads and gravitational load. A modal analysis to ge
Aims. The central region of a circumstellar disk is difficult to resolve in global numerical simulations of collapsing cloud cores, but its effect on the evolution of the entire disk can be significant. Methods. We used numerical hydrodynamics simulations to model the long-term evolution of self-gravitating and viscous circumstellar disks in the thin-disk limit. Simulations start from the gravitat
Time-varying signals, such as sound waves, low-frequency vibrations from the earth, or electrical impulses in the human body, are often non-stationary, meaning their characteristics change over time. Because of this, standard spectral analysis methods, which assume stationary signals, cannot be used for analyzing such signals, as they discard the time-varying dynamics. This necessitates methods fo
This thesis investigates the ignition and flame spread behaviour of engineered wood-based materials, focusing on Medium-Density Fibreboard (MDF), Particleboard, Oriented Strand Board (OSB), and Plywood. Thermal properties, such as thermal conductivity and specific heat capacity, were analysed using Transient Plane Source (TPS) measurements. A new technique has been introduced for measuring therma
Microstrip patch antennas have become essential in modern communication systems due to their compact size and ease of fabrication. However, their performance is often constrained by narrow bandwidth, low radiation efficiency, and low gain, especially in miniaturized designs. The performance limits of microstrip patch antennas are helpful in understanding and overcoming these challenges. These perf
