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Background: Pathology in the noradrenergic A6 locus coeruleus has not been compared with more rostral dopaminergic A9 substantia nigra and A10 ventral tegmental area, and cholinergic Ch4 basal nucleus and Ch1/2 septal regions in the same cases of Parkinson's disease (PD). Objective: To determine whether there is a gradient of caudal to rostral cell loss in PD. Methods: Postmortem brains were colle
Ciliary neurotrophic factor (CNTF) promotes photoreceptor survival but also suppresses electroretinogram (ERG) responses. This has caused concerns about whether CNTF is detrimental to the function of photoreceptors because it is considered to be a potential treatment for retinal degenerative disorders. Here we report that the suppression of ERG responses is attributable to negative regulation of t
We have earlier demonstrated that a Status Epilepticus (SE) during CNS development has long-lasting effects on cholinergic neurotransmission, detectable in vitro and in vivo. In this work, we aimed to localize changes in temporal (T) vs septal (S) hippocampus and to correlate adult CA3 interictal epileptiform discharge (IED) frequency changes to those of Ripples (R) and Fast Ripples (FR) of the Hi
The aim of this study was to derive dietary patterns associated with cardio-metabolic traits and to examine whether these predict prospective changes in these traits and incidence of the metabolic syndrome (iMetS). Subjects from the Malmö Diet and Cancer Study cardiovascular cohort without cardio-metabolic disease and related drug treatments at baseline (n 4071; aged 45-67 years, 40 % men) were in
Sprifermin, recombinant human fibroblast growth factor 18 (rhFGF18), induces cartilage regeneration in knees of patients with osteoarthritis (OA). We hypothesized that a temporal multiphasic process of extracellular matrix (ECM) degradation and formation underlie this effect. We aimed to characterize the temporal ECM remodeling of human knee OA articular cartilage in response to sprifermin treatme
A protective coating is often used on the cladding of wooden facades to limit the absorption of moisture. Low wood moisture content (MC) is essential to obtain satisfactory durability performance. Wood density is known to influence the water sorption and crack formation of uncoated wood. However, the effect of density on the aforementioned behaviors of coated spruce is not yet fully understood. Si
Background: Patients treated for Pediatric Brain Tumors (PBTs) often experience a decline/stagnation in their cognitive functioning.Anumber of potential risk factors for cognitive decline have been identified including gender (female), young age-at-diagnosis, higher baseline IQ, hydrocephalus at diagnosis, treatment with Whole Brain Radiation Therapy (WBRT), and larger radiation field and/or dose.
BACKGROUND: Parkinson's disease (PD) can cause impulsivity with premature responses, but there are several potential mechanisms. We proposed a distinction between poor decision-making and the distortion of temporal perception. Both effects may be present and interact, but with different clinical and pharmacological correlates.OBJECTIVES: This study assessed premature responding during time percept
Charge transfer interactions between C60 and the metal surfaces of Ag(111), Cu(111), Au(111) and Pt(111) have been studied using synchrotron-based photoemission, resonant photoemission and X-ray absorption spectroscopies. By placing the X-ray absorption and valence band spectra on a common binding energy scale, the energetic overlap of the unoccupied molecular orbitals with the density of states o
Atherosclerosis and its clinical consequences are the leading cause of death in the western hemisphere. While many studies throughout the last decades have aimed at understanding the disease, the clinical markers in use today still fail to accurately predict the risks. The role of the current main clinical indicator, low density lipoprotein (LDL), in depositing fat to the vessel wall is believed t
Background: Implementation of clinical health promotion (CHP) aiming at better health gain is slow despite its effect. CHP focuses on potentially modifiable lifestyle risks such as smoking, alcohol, diet, and physical inactivity. An operational program was created to improve implementation. It included patients, staff, and the organization, and it combined existing standards, indicators, documenta
Objective: Glucose dysregulation is an independent risk factor for cardiovascular and neurodegenerative disease development through synaptic dysfunction resulting in cognitive decline. The aim of this study was to study the interplay between impaired glycaemic metabolism (hyperglycaemia and insulin resistance), cardiac stress (cardiac troponin T and N-terminal brain natriuretic peptide) and execut
Aims. The central region of a circumstellar disk is difficult to resolve in global numerical simulations of collapsing cloud cores, but its effect on the evolution of the entire disk can be significant. Methods. We used numerical hydrodynamics simulations to model the long-term evolution of self-gravitating and viscous circumstellar disks in the thin-disk limit. Simulations start from the gravitat
KV_7_2015_inlaga.indd Kemivärlden Biotech med Kemisk Tidskrift. Nr 7 November 201530 Har man följt litteraturen på området läkemedelsrester i miljön är det tydligt att läke- medels beteende ute i naturen är svårare att förutsäga än traditionella mil- jögifter och det behövs nya metoder, säger Ola Svahn, analytisk kemist och forskare vid Högskolan i Kristianstad. Läkemedel har andra funktionella g
https://www.cec.lu.se/sites/cec.lu.se/files/kem_07_2015.pdf - 2026-07-17
Mats Alvesson, University of Lund International PhD Courses Lund University, Sweden 2025 Join us for one or two international PhD courses at Lund University, spring 2024. Our intensive courses offer a combination of lectures, seminars, and workshops for students to learn and receive guided feedback on their PhD projects from leading scholars. The first course covers critical management studies, an
https://www.ehl.lu.se/sites/ehl.lu.se/files/2025-01/Call%20-%20Lund%20PHD%20Courses%202025.pdf - 2026-07-17
Certificate, Half-time review for PhD studies 1/52026-02-25 Certificate, Half-time review for PhD studies Name of PhD student Civic registration no (year of birth,-mo,-day,-no) Date of half-time review The PhD student’s performance at the seminar Component Comments and recommendations Written summary of the thesis project. Oral presentation. Discussion/handling of questions. Activity, progress and
https://www.intramed.lu.se/en/sites/intramed.lu.se.en/files/2026-02/Certificate,%20Half-time%20review%20PhD.pdf - 2026-07-17
Samhällsvetenskapliga fakultetens samverkan med det omgivande samhället Kartläggning och analys CHARLOTTE SIMONSSON & CHRISTOFFER HAHN SAMHÄLLSVETENSKAPLIGA FAKULTETEN | LUNDS UNIVERSITET 2 SAMVERKAN MED DET OMGIVANDE SAMHÄLLET Coverphoto by Petra Francke Layout and typesetting : Media-Tryck, Lund University Lund 2020 3SAMVERKAN MED DET OMGIVANDE SAMHÄLLET Innehåll Inledande om syfte och tillvägag
Kris- och beredskapsplan Samhällsvetenskapliga fakulteten Sida 1 av 8 Fakultetsstyrelsen BESLUT STYR 2024/758 Datum 2024-04-25 Kris- och beredskapsplan för Samhällsvetenskapliga fakulteten Innehållsförteckning Kris- och beredskapsplan för Samhällsvetenskapliga fakulteten ............. 1 1. Inledning ........................................................................................... 2 2. Sy
