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Purpose Our focus was on patients with pediatric acute lymphoblastic leukemia (ALL) who experienced relapse or died without becoming transplantation candidates. The purpose was to outline measures needed to improve the outcome. Patients and Methods We analyzed our population-based 20-year data on 3,385 Nordic children with ALL treated on Nordic Society for Pediatric Hematology and Oncology ALL pro

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This dissertation aims to contribute empirically and theoretically, to the field of Islamology and Religious Studies in general. It does so by investigating the possible relation between Israeli Muslim women’s choice of religious identification and their individual experiences in everyday life transitions. Many of these women are traveling daily from their hometowns or villages to the major cities

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Arsenic is a very potent toxicant. One major susceptibility factor for arsenic-related toxicity is the efficiency of arsenic metabolism. The efficiency, in turn, is associated with non-coding single nucleotide polymorphisms (SNPs) in the arsenic methyltransferase AS3MT on chromosome 10q24. However, the mechanism of action for these SNPs is not yet clarified. Here, we assessed the influence of gene

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Penningtvätt har länge varit ett uppmärksammat problem, men inte förrän på senare år, särskilt efter den 11 september 2001 och terroristattackerna i USA har stora krafttag gjort att bekämpningen av problemet kommit igång. Bekämpningen och förhindrandet av penningtvätt och finansiering av terrorism är även viktigt utifrån ett större perspektiv. Om man kan strypa finanserna för kriminell verksamhet,Money laundering has for a long time been an acknowledged problem, now more than ever. Especially after 9/11 2001 and the terrorist attacks in the USA, joint efforts have made combating the problem a serious matter. Combating and prevention of money laundering and terrorism financing is also important from a larger perspective. If you can close off finances of criminal activity, you are one step c

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Problemformulering: Vilka åtgärder kan vidtas för att bemöta de utvecklingsbehov Miljöbyggnad står inför gällande betygssystemets och ingående indikatorers utformning? Syfte: Syftet är att i första hand utvärdera betygssättningssystemet i Miljöbyggnad. I andra hand ska förbättrande åtgärder utarbetas och provas. Arbetet ska avse vara en del i underlaget inför utvecklingen av systemet. SlutsatserThe Issue/problem: What measures can be taken to address the development needs Miljöbyggnad are facing regarding its rating system and detailed design of indicators? The Purpose: The purpose is primarily to evaluate the rating system in Miljöbyggnad. Secondly, improvement measures will be developed and tested. The work will relate to being part of the basis for the development of the system. The

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Arbetet är utfört åt skogsforskningsstationen Mógilsá som ligger strax norr om Reykjavik. Forskningen inom Mógilsá bedrivs inom delar av eller för hela Island med inriktning inom exempelvis dendrokronologi, proveniensförsök, och studier av insekter. Sedan 1900-talets början har inplantering av exotiska trädarter blivit allt vanligare och i en allt större skala. Syften med inplanteringen är bland aThis study was made in an attempt to give the forest research centre Mógilsá a produced tetratherm map and a better understanding of how topography and temperature influence the growth of two tree species. The digital tetratherm map model, covering the northern part of Iceland, was developed to investigate the correlation between tetratherm and the growth of Picea sitchensis and Larix (sukaczewii

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The maritime transportation of hazardous cargo has created a sometimes intense dispute between the shipping industry and coastal states. The arguments feeding this discussion are the right of innocent passage, claimed by shipping states, and on the other hand, the obligation to protect the environment stressed by coastal states. Two sets of rules, both codified in international law, stand in confl

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Öresundsregionen är en mycket aktiv region med över tjugotusen människor som arbetspendlar dagligen. Rent fysiskt är det idag lättare att pendla över Öresund än förr, tack vare Öresundsbron. Det finns dock andra hinder. Sveriges regler för sociala avgifter och på inkomstskatteområdet skiljer sig en hel del från Danmarks och denna diskrepans kan ge upphov till vissa problem. Uppsatsen är inriktad p

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Uppsatsens syfte är att undersöka återförsäljares uppsägningsskydd och rätt till ersättning vid avtalets upphörande. För ett företag som önskar etablera sig på en ny marknad gäller det att välja rätt exploateringsmetod. Ett alternativ är då att utse en representant som säljer produkten på den nya marknaden. En lokal representant som känner till marknaden och eventuellt redan har ett etablerat försThe purpose of this essay is to examine the retailer’s dismissal protection and the right to compensation for termination of contract. For a company who wishes to establish themselves in a new market it is important to choose the right development approach. An alternative is then to appoint a representative who sells the product in the new market. A local representative who knows the market and po

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The laminate flooring company Pergo (Europe) AB has during the last years identified an increasing market demand for customized flooring solutions. In the autumn of 2004 Pergo had no standardized product offer and the existing administrative process was not suited to produce and deliver customized products. Experiments concerning a new décor production technique with extensive potential based on d

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Stora inlandsisar har vid upprepade tillfällen täckt Sveriges yta och den senast inlandsisen började dra sig tillbaka från Bohusläns kust för ca 15 000 år sedan. En inlandsis rör sig sakta framåt över underlaget och när den gör så kan stenar infrusna i isens botten skrapa berggrunden och bilda långa räfflor, flisor kan brytas loss ur berget och stora block kan också frysa fast i isen och transportRamsvikslandet on the Swedish west coast is characterized by exposed bedrock hills with numerous glacial erosional forms. Previous research in the area has mostly focused on individual forms and their relation to the larger forms, such as roches moutonnées. This study takes a more large-scale perspective and aims to reconstruct the subglacial processes based on the erosional forms and their distri

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In previous years, substantial research has focused on walkability, primarily examining how the built environment affects walking behavior. However, these studies have predominantly defined walkability through physical and social factors, with limited exploration of its spatial dimension. This article seeks to address this gap by examining the spatiality of walkability through Lefebvre’s spatial tIn previous years, substantial research has focused on walkability, primarily examining how the built environment affects walking behavior. However, these studies have predominantly defined walkability through physical and social factors, with limited exploration of its spatial dimension. This article seeks to address this gap by examining the spatiality of walkability through Lefebvre’s spatial t

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Background: Ultrafiltration (UF) insufficiency in peritoneal dialysis (PD) often leads to transfer to hemodialysis. Therefore, strategies to prolong time on therapy are needed. The use of a combined crystalloid and colloid solution, also called bimodal PD, can help improve UF. Methods: We propose a method for reconstituting bimodal solutions. Three bimodal PD solutions, with respectively 100 ml (s

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SummaryElevated HDL-C levels are generally regarded as prognostically favorable in cardiovascular disease. Our study shows that higher HDL cholesterol levels are prospectively associated with 18% increased risk of new-onset fractures in men but not in women. Higher HDL cholesterol may be a novel risk factor for developing fractures in men.PurposeIncreased high-density lipoprotein cholesterol (HDL-

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Background Long-term pathological breathlessness is a life-limiting symptom that risks taking control of the individual’s life. We aimed to evaluate how locus of control (LOC), an individual’s perceived control of present and past life events, relates to breathlessness in a middle-aged general population. Methods A population-based, cross-sectional analysis of people aged 50–64 years was conducted

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Background and objective: Although cardiovascular toxicity from modern systemic treatments in metastatic hormone-sensitive prostate cancer (mHSPC) remains a concern, real-world data are limited. We aimed to characterise patients treated for mHSPC across multiple large cohorts and estimate cardiovascular adverse event (AE) risks. Methods: Leveraging PIONEER's Big Data platform, with databases stand

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Aim Postural orthostatic tachycardia syndrome (POTS) is a disorder with cardiovascular autonomic dysfunction where multiple and variable symptoms are common, including those from the peripheral and enteric nervous systems. We aimed to investigate subjective and objective signs of small and large fiber neuropathy in a Swedish POTS cohort compared with healthy controls. Secondly, we wanted to examin