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Biological Activities of Natural and Semi-Synthetic Pseudo-Guaianolides: Inhibition of Transcription Factors

Popular Abstract in English The sesquiterpene lactones is an important group of natural products, and they are present in many medicinal plants. Their most important biological activities are anti-inflammatory and anti-cancer activity, although for many decades their potential use as drugs was dismissed. The main reason for this was their alkylating capacity, reacting with thiol functions in proteDamsin (1) is a natural sesquiterpene lactone (SL) isolated from Ambrosia arborescens Mill., a plant used in the Andes as antiinflammatory medicine. This natural product is an inhibitor of NF- κB, a protein complex that controls the transcription of many genes in mammalian cells, and has a potential for standing model for the development of new anti-cancer lead structures. In order to improve the

New treatments in hemophilia: insights for the clinician.

Hemophilia has evolved from an often fatal hereditary bleeding disorder to a disorder for which safe and effective treatment is available. However, there are several challenges remaining in the treatment of hemophilia. Prophylaxis to prevent bleeding is costly and requires frequent intravenous injections, which are cumbersome for patients. Venous access is often difficult to achieve, especially in

Synthesis, Radiolabeling, and in Vitro and in Vivo Evaluation of [ 18 F]ENL30 : A Potential PET Radiotracer for the 5-HT 7 Receptor

The 5-HT 7 receptor (5-HT 7 R) is involved in a broad range of physiological conditions and disorders. Currently, there is no validated clinical positron emission tomography (PET) tracer available; however, we have recently developed a promising 11 C-labeled candidate. In this project, we aimed to further extend our efforts and develop an 18 F-labeled derivative, coined [ 18 F]ENL30. Fluorin

Facilitating the Adoption of People Analytics Dashboards in HR: Investigating the Role of Training, Leadership Support, and WIIFM Campaigns Using the Technology Acceptance Model

Adoption of people analytics (PA) tools in human resources (HR) remains limited, despite increasing efforts to democratize data across organizations. This thesis examined how three change management facilitators, namely leadership support, training programs, and “What’s In It For Me” campaigns, relate to HR professionals’ use of PA dashboards. Using the Technology Acceptance Model (TAM) as a frame

Vanliga människor med ovanliga samlingar

Under 2021 frågade Historiska museet sina besökare: Vad samlar du på? Och kan du tänka dig att visa upp din samling? Vi fick svar – många svar. Här är några av dessa. Uranglas. Muminsaker. Bilmodeller. Seriealbum, plektrum, parfymer. Glasögon, böcker. Mangagrejer, gamingfigurer, pokémonprylar och flaskor med Ramune-läsk eller energidrycken Monster. Brädspel. Guld- och platinaskivor. Eller varför i

https://www.historiskamuseet.lu.se/privata-samlare - 2026-05-05

”Mer strålkastare på forskarna precis som på toppidrottarna!” – Vetenskap och Hälsa

”Mer strålkastare på forskarna precis som på toppidrottarna!” – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök ”Mer strålkastare på forskarna precis som på toppidrottarna!” 2015-03-26 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Att jag och min forskning h

https://www.vetenskaphalsa.se/mer-stralkastare-pa-forskarna-precis-som-pa-toppidrottarna/ - 2026-05-05

2023-09-25 LSK-protokoll-webb

2023-09-25 Protokoll LSK Sida 1 av 5 Lokal skyddskommitté PROTOKOLL Diarienummer V 2023/2095 Datum 2023-09-25 Protokoll lokal skyddskommitté Närvarande Karin Hall, stf ordförande Catrin Malmström, kansli N, ledamot Jessica Abbott, biologiska institutionen, ledamot Leif Bülow, kemiska institutionen, ledamot Magnus Alsterfjord, huvudskyddsombud Bengt Meuller, över- och huvudskyddsombud Carina Rasmus

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2023-12/2023-09-25%20LSK-protokoll-webb.pdf - 2026-05-06

Diabetes – Sida 4 – Vetenskap och Hälsa

Diabetes – Sida 4 – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kategori: Diabetes Modern diabetesbehandling kan orsaka allergi 2021-02-23 Många personer med typ 1-diabetes använder moderna glukossensorer och insulinpumpar. Insulin ges via pumpen och blodsockret mäts kontinuerligt via se

https://www.vetenskaphalsa.se/kategori/diabetes/page/4/ - 2026-05-04

Environmental compensation as a policy tool in Swedish municipal planning

In the struggle to reach the national environmental policy objectives, environmental compensation has emerged as a possible policy tool that may contribute to achieving the objectives. In Sweden, environmental compensation is legally mandated mainly in cases of exploitation within Natura 2000 areas and nature reserves, which is handled through the Swedish Environmental Code. In contrast, regulator

Hand and Arm Function in Persons with De Novo Parkinson’s Disease

Objective: To evaluate hand and arm function and its association with motor symptoms as well as activities of daily living (ADL) in de novo Parkinson’s disease (PD).Background: Motor symptoms and disability in upper limb are common in PD and usually assessed using Unified PD Rating Scale (UPDRS). Activities, like reaching, grasping, manipulating objects, writing, dressing, and eating, may be more Objective: To evaluate hand and arm function and its association with motor symptoms as well as activities of daily living (ADL) in de novo Parkinson’s disease (PD).Background: Motor symptoms and disability in upper limb are common in PD and usually assessed using Unified PD Rating Scale (UPDRS). Activities, like reaching, grasping, manipulating objects, writing, dressing, and eating, may be more

Time-Frequency Analysis of the Auditory Brainstem Response

This thesis is about time-frequency analysis of the brainstem auditory evoked potential (BAEP). The work can be divided into two parts. One part where a model is built up from a very simple example to a more complex model resulting in a model consisting of a sum of sinusoids with stochastic starting points and amplitudes. Dierent time-frequency methods have been evaluated for these models and the

Feathers by day, membranes by night - Aerodynamic performance in bird and bat flight

Popular Abstract in English Animal flight has always intrigued people, and different aspects of animal flight have therefore widely been studied by biologists, physicists and engineers. At least to me, the aspect concerning the aerodynamics of animal flight in particular is very interesting because of the complex temporal varying wake dynamics as a result of continually wing morphing in flapping fThe efficiency and performance of a flying animal is directly related to the aerodynamics around its body and flapping wings. Here, I have developed methods for quantifying the wake dynamics around a flying animal. The results are used to estimate the aerodynamic performance of flapping flight. Using these methods, I have studied flight of the Pied Flycatcher (Ficedula hypoleuca), the Pallas’ Long

Synen på skrivande : Föreställningar om skrivande i mediedebatter och gymnasieskolans läroplaner

This dissertation is about the view of writing. One of the intentions of the study is to analyse different notions of writing that become manifest in media debates about student writing. Another intention is to analyse conceptions of writing in curricula and course plans for upper secondary school in Sweden from 1970 to 2011. Drawing from theories of critical discourse analysis, the study aims atThis dissertation is about the view of writing. One of the intentions of the study is to analyse different notions of writing that become manifest in media debates about student writing. Another intention is to analyse conceptions of writing in curricula and course plans for upper secondary school in Sweden from 1970 to 2011. Drawing from theories of critical discourse analysis, the study aims at

stroke – Sida 2 – Vetenskap och Hälsa

stroke – Sida 2 – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: stroke Föreläsning om stroke 14 maj 2019-05-08 Välkomna till en eftermiddag med föreläsningar och blodtrycksmätningar på Skånes universitetssjukhus i Malmö i samband med den internationella strokedagen. NÄR? Tisdagen

https://www.vetenskaphalsa.se/tag/stroke/page/2/ - 2026-05-04

Straffrättslig nödrätt - Försvarlighetsbedömningen i 24 kap. 4 § BrB

Necessity is a justification rule in 24th chapter 4 § in the Swedish Penal Code (Sw. brottsbalken). The clause is applicable when a danger threatens life, health, property or another interest that is protected by the legal system. An act committed in an emergency is seen as a crime only if it, with regard to the nature of the danger, the damage that is caused and the other circumstances, is unjust

Foreskrifter-rorande-hantering-av-ekonomiska-intressekonflikter-relaterade-till-viss-amerikansk-fors

Brevmall Postadress Box 117, 221 00 Lund Besöksadress Paradisgatan 5C Telefon 046-222 77 71, 046-222 00 00 E-post anneli.wiklander@fs.lu.se Rektor Föreskrifter rörande hantering av ekonomiska intresse- konflikter relaterade till viss amerikansk forskningsfinansiering Bakgrund I samband med ansökan om forskningsbidrag och för att kunna ta emot forskningsmedel från USA:s statliga finansiärer, särski

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/foreskrifter-rorande-hantering-av-ekonomiska-intressekonflikter-relaterade-till-viss-amerikansk-forskningsfinansiering.pdf - 2026-05-06

Automation and simulation of a robot cell for stud bolt welding

The importance of sustainable and effective energy usage is rapidly growing. SWEP International AB leads the manufacturing of brazed plate heat exchangers that offer effective heating and cooling applications used in various systems and industries. Stud bolts are manually welded onto the heat exchanger surface in their manufacturing process. A project to fully automate this process using an indust

Njurar och urinvägar – Sida 2 – Vetenskap och Hälsa

Njurar och urinvägar – Sida 2 – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kategori: Njurar och urinvägar Målstyrt enzym från mördarbakterier räddar njursjuka 2018-02-26 – IdeS-enzymet är det mest överraskande fyndet under min forskarbana. Enzymet kommer från en farlig bakterie, men kan

https://www.vetenskaphalsa.se/kategori/njurar-och-urinvagar/page/2/ - 2026-05-04

Parkinsons sjukdom – Vetenskap och Hälsa

Parkinsons sjukdom – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: Parkinsons sjukdom Hjärnväg bakom impulsivitet vid Parkinsonsbehandling upptäckt 2025-08-13 En djurstudie vid Lunds universitet visar för första gången hur olika Parkinsonläkemedel påverkar hjärnans aktivitet på sk

https://www.vetenskaphalsa.se/tag/parkinsons-sjukdom/ - 2026-05-04