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Kinetics and mechanism of oxidation of the anti-tubercular prodrug isoniazid and its analog by iridium(IV) as models for biological redox systems

A complex reaction mechanism of oxidation of the anti-tubercular prodrug isoniazid (isonicotinic hydrazide, INH) by [IrCl6]2− as a model for redox processes of such drugs in biological systems has been studied in aqueous solution as a function of pH between 0 and 8.5. Similar experiments have been performed with its isomer nicotinic hydrazide (NH). All reactions are overall second-order, first-ord

Investigating the Potential of an Integrated Coolant Waste Heat Recovery System in an HD Engine Using PPC Operation

With the increasing focus on reducing emissions and making fuel efficient vehicles within the automotive industry over the past few years, new methods are constantly being investigated to improve the efficiency of the powertrain. One such method is recovering waste heat from the exhaust gases as well as the coolant using a thermodynamic cycle such as a Rankine cycle. However, most studies looking

A Novel Approach to Economic Evaluation of Infrastructure? Examining the Benefit Analyses in the Swedish High-Speed Rail Project

The purpose of this paper is to describe a novel approach to economic evaluation of infrastructure, the benefit analyses in the Swedish high-speed rail project, and to analyse what role these can play in the decision-making process. The reports identify benefits from infrastructure investment at the local level and were intended to assist in making co-financing agreements and as a basis for decisi