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The action of three matrix metalloproteinases (MMPs), 72- and 95-kDa gelatinases (MMP-2 and MMP-9) and PUMP (MMP-7), and a cysteine proteinase, cathepsin B, were investigated on aggrecan the major proteoglycan of cartilage. All the enzymes cleaved aggrecan although the activity of the 95-kDa gelatinase was very low. Specific cleavage sites were investigated following incubation with a purified agg

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Stress-related exhaustion is an increasingly focused phenomenon, although scientifically not yet fully conceptualised. This is perhaps partly due to the fact that the distinction between exhaustion and other already established concepts, such as depression, is not clear. This study explores whether exhaustion can be differentiated from depression and anxiety, by means of introducing the SF-36 vita

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The purpose of the study was to increase self-archiving of scientific articles in Swedish open archives and thus contribute to the dissemination and increased visibility of Swedish research and to a greater impact for the individual researcher. We wanted to find out what obstacles may occur in the self-archiving process and how the database SHERPA/RoMEO functions as support for control of the publ

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Caldicellulosiruptor saccharolyticus displays superior H(2) yields on a wide range of carbon sources provided that lactate formation is avoided. Nevertheless, a low lactate flux is initiated as the growth rate declined in the transition to the stationary phase, which coincides with a drastic decrease in the glucose consumption and acetate production fluxes. In addition, the decrease in growth rate

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The general population is exposed to cadmium from food and smoking. Cadmium is a widely spread toxic pollutant that seems to be associated with cardiovascular diseases, although little is known if it contributes to the occurrence of atherosclerotic plaques and the process whereby plaques become vulnerable and are prone to rupture. We tested the hypotheses that cadmium exposure is associated not on

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In business controllers’ work on budgeting, considered as a classic decision-making process in organisations, it is consistently indicated that enterprise resource planning (ERP) systems, business intelligence (BI) and spreadsheets are commonly applied to assist the process. An academic research contribution on this topic is few. Most available research concentrates on ERP systems but it mentions

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While the international community would like to think it does not happen crimes are committed by peacekeepers. There is a growing prevalence of the crimes of trafficking, rape, sexual slavery and enforced prostitution being perpetrated by peacekeepers. These are all gender-specific crimes against women. They are also the crimes that most often remain unpunished, especially when committed by peacek

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BackgroundAround one fourth of patients with colorectal cancer present themselves with distant metastases at the time of diagnosis, and one additional one fifth of the patients will develop distant metastases during the disease, most commonly in the liver.Surgical treatment such as liver resection or ablation, often combined with chemotherapy and targeted therapy, is the only treatment option with

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Aim: To explore whether physiotherapy use is increased after hospitalization with COVID-19 with or without respiratory support vs. other respiratory tract infections (RTI). Methods: In all Norwegian residents aged 18–80 years who were hospitalized with COVID-19 (N = 5,344) or other RTI (N = 82,235) between July 1st 2017 and August 1st 2021, we used a pre-post study design to explore the weekly ind

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Massive multiple-input multiple-output (MIMO) is expected to be a vital component in future 5G systems. As such, there is a need for new modeling in order to investigate the performance of massive MIMO not only at the physical layer but also higher up the networking stack. In this paper, we present general optimization models for massive MIMO, based on mixed-integer programming and compatible sets

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The production of exclusive γγ→μ+μ− events in proton–proton collisions at a centre-of-mass energy of 13 TeV is measured with the ATLAS detector at the LHC, using data corresponding to an integrated luminosity of 3.2 fb−1. The measurement is performed for a dimuon invariant mass of 12GeV

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At synchrotron light storage rings there is demand for serving high-brilliance users requesting multibunch operation while simultaneously serving timing users who require single-bunch operation. One method to accomplish this is PPRE developed and currently in user operation at BESSY II. In the method, the transverse emittance of one of the bunches in the bunch train is increased by an incoherent b

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Self‐similar situations are idealized states often referred to in continuum mechanics. Such a situation is generally expected when the formulated problem only involves one significant length parameter. The state at a stationary or at a steadily moving concentrated load may be self‐similar. In heat conductivity, the progressive phase transformation near a point‐shaped heat source results in a self‐

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Background: Treating patients in cardiac arrest (CA) with mechanical chest compressions (MCC) during percutaneous coronary intervention (PCI) is now routine in many coronary catheterization laboratories (cath-lab) and more aggressive treatment modalities, including extracorporeal CPR are becoming more common. The cath-lab setting enables monitoring of vital physiological parameters and other clini

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Purpose: Few studies have reported non-acute long-term morbidity rates in children with intestinal malrotation. The aim of this study was to investigate the rate of constipation in children undergoing Ladd's procedure for isolated intestinal malrotation. Methods: This retrospective study included children aged <15 years who underwent Ladd's procedure for intestinal malrotation between 2001 and 201

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Seaweed cultivation is a large industry worldwide, but production in Europe is small compared to production in Asian countries. In the EU, the motivations for seaweed farming may be seen from two perspectives; one being economic growth through biomass production and the other being the provisioning of ecosystem services such as mitigating eutrophication. In this paper, we assess the economic poten

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PURPOSE: The aim of this study was to evaluate how relatives of patients with an ostomy rated the various aspects of care, how they perceived the quality of the care provided, and how they ranked their involvement in the care. Patients' satisfaction was also sought, particularly their perception of relatives' involvement.DESIGN: Descriptive cross-sectional.SETTINGS AND SUBJECTS: The study comprise