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The time-course and magnitude of fibre outgrowth from septal suspension grafts injected into the previously denervated hippocampal formation was monitored by measurements of choline acetyltransferase (ChAT), and the activity of the grafted neurons was assessed by measurements of [14C]acetylcholine (ACh) synthesis from [14C]glucose in vitro. Graft-derived ChAT activity was barely detectable 10 days
The ICAO approach to risk management is essentially a technical model based on an engineering process viewpoint and is more applicable in concept to stable systems, such as chemical and nuclear industries. If airlines are to manage risk in a proactive manner they need to apply risk detection tools that provide real time and continuous systems oversight. This paper describes briefly the systems ap
The modern requirements on power transmissions focus on energy efficiency, low noise and dynamic vibrations, and power density. In order to meet these requirements, the gear wheels must be manufactured to very high precision. Additionally, it should be economical to manufacture these gears within the tight requested tolerances. Gears manufactured within automotive, truck, and construction equipmen
Cytogenetic analyses of a consecutive series of 67 paediatric (median age 8 years; range 0-17) de novo acute myeloid leukaemia (AML) patients revealed aberrations in 55 (82%) cases. The most common subgroups were KMT2A rearrangement (29%), normal karyotype (15%), RUNX1-RUNX1T1 (10%), deletions of 5q, 7q and/or 17p (9%), myeloid leukaemia associated with Down syndrome (7%), PML-RARA (7%) and CBFB-M
BACKGROUND: Chronic obstructive pulmonary disease is a leading cause of mortality, and associated with increased healthcare utilization and healthcare expenditure. In several countries, morbidity-based systems have changed the way resources are allocated in general practice. In primary care, fee-for-services tariffs are often based on political negotiation rather than costing systems. The potentia
Importance: The prognostic impact of parenteral nutrition duration (PND) on retinopathy of prematurity (ROP) is not well studied. Safe prediction models can help optimize ROP screening by effectively discriminating high-risk from low-risk infants. Objective: To evaluate the prognostic value of PND on ROP; to update and validate the Digital ROP (DIGIROP) 2.0 birth into prescreen and screen predicti
Films of poly-L-leucine, poly-L-valine, and poly-L-isoleucine have been studied at the air-water interface by surface balance experiments. In addition, Langmuir-Blodgett (LB) films of these polypeptides deposited onto quartz and mica have been studied by circular dichroism (CD) spectroscopy and atomic force microscopy (AFM) to elucidate the effects of polypeptide conformation and spreading agent (
Background: Weight gain and hypertension are well known adverse effects of treatment with high-dose glucocorticoids. Objective: To evaluate the effects of 2 years of low-dose glucocorticoid treatment in rheumatoid arthritis (RA). Design: Pooled analysis of 5 randomized controlled trials with 2-year interventions allowing concomitant treatment with disease-modifying antirheumatic drugs. Setting: 12
Introduction: The Bogong moth Agrotis infusa is well known for its remarkable annual round-trip migration from its breeding grounds across eastern and southern Australia to its aestivation sites in the Australian Alps, to which it provides an important annual influx of nutrients. Over recent years, we have benefited from a growing understanding of the navigational abilities of the Bogong moth. Mea
This short report is one of a series of outputs to flow from the international,interdisciplinary project ‘Looking back to move forwards: a social and cultural historyof home heating’ (JUSTHEAT), funded through the Collaboration of Humanities andSocial Sciences in Europe (CHANSE) initiative, which began in 2022 and runs until2025. Within this project, we aim to understand how major changes to home
The COVID-19 pandemic placed health sectors across the world under great pressure in terms of acute care and infection control. Policies responding to the latter led to a change in working practices among health practitioners, including nurses. The changes included establishing new patterns and protocols of risk work to mitigate infection risk in hospitals, but these new ways of working were somew
Help-seeking related to depression and suicidal ideations is frequent in internet forums. Forum threads concerning these topics often receive much interest through active replies but are also read by numerous passive users. Previous research indicates that such interactions may be helpful for the help-seeker, even if the underlying mechanisms are less clear. Meanwhile, some studies also suggest th
When the politically active Ukrainian community in Edmonton, Alberta, gathered in late November 2019 for their annual commemorations of the massive famine that ravished the Ukrainian Soviet Republic in 1932–33, their rituals followed established patterns. The politically well-connected Ukrainian Canadian Congress (UCC) held its choreographed gatherings in the
Background: Surgical site infection (SSI) after acute hip fracture surgery is a devastating complication associated with increased suffering and mortality. The aim of the study was to investigate early SSI, sepsis, pneumonia and urinary tract infections over five years, before and after the implementation of the Safe Hands project. Methods: This was a single-centre observational study with a 5-yea
Popular Abstract in Swedish Fysikalisk modellering och reglering av motorer En stor del av dagens forskning inom förbränningsmotorer är inriktad på att minska bränsleförbrukning och emissioner, utsläpp. De traditionella bensinmotorerna har förhållandevis låga emissionsnivåer medan dieselmotorerna har en lägre bränsleförbrukning. De förbränningskoncept som studeras i avhandlingen Physical ModelingThe topic of this thesis is model-based control of two combustion engine concepts, Homogeneous Charge Compression Ignition (HCCI) and Partially Premixed Combustion (PPC), using physics-based models. The studied combustion concepts hold promise of reducing the emission levels and fuel consumption of internal combustion engines. A cycle-to-cycle model of HCCI, including heat losses to the cylinder
There is limited information regarding new ulceration following the healing of ischaemic foot ulcers in diabetic patients. Our aim is to study new ulcerations in the same foot as the previous ulcer(s) in patients with diabetes and severe peripheral artery disease (PAD).
Gonadotropin-releasing hormone (GnRH) 1 and 2 and luteinizing hormone (LH) receptors have been described in the gastrointestinal tract. We have previously demonstrated antibodies in serum against GnRH1 in patients with gastrointestinal dysfunction and diabetes mellitus, and antibodies against GnRH receptor, LH, and LH receptor in patients with infertility. The aim of this study was to search for t
Estimates of relevant source area of pollen (RSAP) and relative pollen productivity (PPE) are critical parameters for quantitative reconstructions of past vegetation and land cover. This study provides estimates for PPE relative to Poaceae for ten taxa, characterizing the cultural landscape of south Estonia and the RSAP for 40 lakes with an average radius of approximately 100 m (22-274 m, average
Replantation in the upper extremity is a well-established microsurgical procedure. Many have reported patients' satisfaction and functional measurements.The aim was to investigate the long time consequences as activity limitations in hand/arm, the general health and cold sensitivity after a replantation or revascularization in the upper extremity and to examine if sense of coherence (SOC) can be a
