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The recently introduced method of `signal apparition' offers a fundamentally different approach to separation of multiple interfering sources, by using a periodic sequence of source signatures along one source line. This leads to exact separation of signals in diamond-shaped regions of the frequency-wavenumber domain which are twice as large compared to those recovered by other methods. In this pa
The problem of estimating receiver or sender node positions from measured receiver-sender distances is a key issue in different applications such as microphone array calibration, radio antenna array calibration, mapping and positioning using UWB or using round-trip-time measurements between mobile phones and WiFi-units. In this paper we address the problem of optimally estimating a receiver positi
In this paper we study the problem of estimating receiver and sender positions from time-difference-of-arrival measurements, assuming an unknown constant time-difference-of-arrival offset. This problem is relevant for example for repetitive sound events. In this paper it is shown that there are three minimal cases to the problem. One of these (the five receiver, five sender problem) is of particul
The 1918 influenza pandemic had not only a massive instant death toll but also lasting effects on its survivors. Several studies have shown that children born in 1919, and thus exposed to the H1N1 virus in utero, experienced worse health and socioeconomic outcomes in older ages than surrounding birth cohorts. This study combines several sources of contemporary statistics with full-population indiv
BACKGROUND AND OBJECTIVES: Degarelix is a gonadotropin-releasing hormone antagonist registered for the treatment of advanced hormone-dependent prostate cancer. Treatment causing androgen deprivation is associated with QT prolongation and this study investigated whether degarelix at supratherapeutic concentrations has an intrinsic effect per se on cardiac repolarisation and the QT interval.METHODS:
Background: Namibia has made significant gains in the fight against malaria, with a target of elimination by 2023. We examined the genotype and allele frequencies of glucose-6-phosphate dehydrogenase (G6PD) deficiency to inform decisions on primaquine use, as we recently detected clusters of Plasmodium ovale curtisi in Kavango. Methods: A multistaged cross-sectional sampling method was used to enr
Klimatkrisen framstår mer och mer som det största hot människan någonsin ställts inför. Även om det politiska svaret kan beskrivas som avvaktande, pågår arbete för att på olika sätt minska klimatförändringarnas effekter, och hantera de risker vi kommer att ställas inför. Världssamfundet är enigt. Den globala medeltemperaturen bör inte öka med mer än 2 grader, och helst inte mer än 1,5 grader, jämfClimate change is a growing threat to mankind. The message from the scientific community is clear: we need to act fast and profoundly. The political response has, however, been slow. The likelihood that we will be able to meet our political climate goals only by reducing emissions is slim. Meanwhile is the interest around ways to capture carbon dioxide that has already been emitted on the rise. In
In a recent article for this journal, Stuart, D., Gunderson, R., and Petersen, B. [(2017). Climate change and the Polanyian counter-movement: carbon markets or degrowth? New political economy, 1–14. doi:10.1080/13563467.2017.1417364] discuss solutions to climate change in terms of Karl Polanyi’s concept of the double movement. They set up their argument as a critique of my own article on the topic
The purpose of this article is to explore the intersections between genes, the body and the lived experience of a genetic disease. This article is based on empirical material from a study on how individuals affected by Huntington’s disease experience their everyday life. This study identified two themes that represent and capture the experience of the affected individuals. The themes are (1) notic
Social interaction sensing and indoor positioning using are widely researched. However, many use cases only need to determine proximity, and not the exact location. In this paper, we describe two methods to determine which meeting each user is participating in using proximity data collected from a challenging real-world office.We show that the RSSI threshold approach to detecting proximity is not
Despite of having no explicit shape model, multi-atlas approaches to image segmentation have proved to be a top-performer for several diverse datasets and imaging modalities. In this paper, we show how one can directly incorporate shape regularization into the multi-atlas framework. Unlike traditional multi-atlas methods, our proposed approach does not rely on label fusion on the voxel level. Inst
Carbonate veins in the igneous basement and in the lithified sedimentary cover of the Cocos Ridge at International Ocean Discovery Program (IODP) Hole 344-U1414A reveal the hydrologic system and fluid-rock interactions. IODP Hole 344-U1414A was drilled on the northern flank of the Cocos Ridge and is situated 1 km seaward from the Middle America Trench offshore Costa Rica. Isotopic and elemental co
Background: A crucial step in image fusion for intraoperative guidance during endovascular procedures is the registration of preoperative computed tomography angiography (CTA) with intraoperative Cone Beam CT (CBCT). Automatic tools for image registration facilitate the 3D image guidance workflow. However their performance is not always satisfactory. The aim of this study is to assess the accuracy
In this paper we address the problem of registering and merging two maps in two dimensions, given covariance estimates of the two maps. We show that if two maps are given in the same coordinate system, then the problem of merging them in a statistically optimal way can be formulated as a linear least squares problem, but if they are given in different coordinate systems as well the problem becomes
The field of high dynamic range imaging addresses the problem of capturing and displaying the large range of luminance levels found in the world, using devices with limited dynamic range. In this paper we present a novel tone mapping algorithm that is based on K-means clustering. Using dynamic programming we are able to not only solve the clustering problem efficiently, but also find the global op
The central problem of this thesis is locating several sources and simultaneously locating the positions of the sensors. The measurements captured by the sensors are time of arrival (TOA), time difference of arrival (TDOA), unsynchronized TDOA, or received signal strength indication (RSSI), all a variation of distance measurement between sensors and sources. Signals can be either sound or radio fo
A large number of medical examinations involve images in some way. Images can be used for diagnostics, follow-up studies and treatment planning. In this thesis mathematical methods have been developed and adapted in order to analyze medical images. Several applications for different imaging modalities have been studied and the usefulness of such methods is demonstrated.A complete system for detect
Various improvements were made to a state-of-the-art aerosol–cloud model and comparison of the model results with observations from field campaigns was performed. The strength of this aerosol–cloud model is in its ability to explicitly resolve all the known modes of heterogeneous cloud droplet activation and ice crystal nucleation. The model links cloud particle activation with the aerosol loading
Here, we first present a follow-up to a previous work by our group on the problematic of molecular dynamics simulations of intrinsically disordered proteins (IDPs) [Henriques et al. J. Chem. Theory Comput. 2015, 11, 3420−3431], using the recently developed TIP4P-D water model. When used in conjunction with the standard AMBER ff99SB-ILDN force field and applied to the simulation of Histatin 5, our
The problem of estimating receiver-sender node positionsfrom measured receiver-sender distances is a key issue indifferent applications such as microphone array calibration, radioantenna array calibration, mapping and positioning using ultrawidebandand mapping and positioning using round-trip-timemeasurements between mobile phones and Wi-Fi-units. Thanks torecent research in this area we have an i
